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Persons with narcolepsy with cataplexy have low levels of protein thought to help regulate sleep

Persons with narcolepsy with cataplexy have low levels of cerebrospinal fluid (CSF) hypocretin-1, a protein thought to help regulate sleep and wakefulness, according to a study published in the August 1st issue of the journal SLEEP.

2 Aug 2007

Biological markers of narcolepsy

The first report to identify the biological markers of narcolepsy using gene expression in white blood cells finds that the MX2 gene, which is relevant to the immune system, is significantly less expressed in narcoleptics compared with normal subjects.

2 Aug 2007

People with narcolepsy have a high frequency of REM sleep without muscle atonia

Normal rapid eye movement (REM) sleep is characterized by tonic features, including cortical electroencephalogram (EEG) desynchronization and muscle atonia, as well as phasic events, including bursts of REM, phasic activities of both chin and limb electromyography (EMG), and cardiorespiratory variability.

4 Jul 2007

Cataplexy News and Research

Persons with narcolepsy with cataplexy have low levels of protein thought to help regulate sleep

Biological markers of narcolepsy

People with narcolepsy have a high frequency of REM sleep without muscle atonia

Sleep disorders common among police officers

Link between Parkinson's and narcolepsy

Gender affects the way a person's brain responds to humor

What a joke! women laugh more than men

Histamine is key to narcolepsy

Brain cells containing the chemical histamine are critical for waking

Drug Based on Brain Chemical Could End Narcolepsy and Insomnia

Innovations in baculovirus–insect cell expression systems

Compound Management and its Crucial Role in Early Pharmaceutical Research

Natural products: the next frontier in drug discovery

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