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Nanoviricides lead anti-HIV candidate as good as HAART cocktail therapy

NanoViricides, Inc. reports that its lead anti-HIV candidate achieved anti-HIV efficacy equivalent to a HAART triple drug cocktail in its recently completed animal study.

25 Jul 2011

Threshold reports initiation of TH-302 and bevacizumab clinical trial for astrocytoma

Threshold Pharmaceuticals, Inc., today announced that the University of Texas at San Antonio initiated a clinical trial of TH-302 in combination with bevacizumab in patients with recurrent high grade astrocytoma including glioblastoma.

25 Jul 2011

Researchers characterise protein complex linked to malaria and toxoplasmosis

Maryse Lebrun, Research Director at Inserm, and her fellow researchers at the Laboratoire Dynamique des interactions membranaires normales et pathologiques, have characterised a protein complex that allows the agents that cause malaria and toxoplasmosis to infect host cells.

25 Jul 2011

New WHO policy recommendation warns against use of blood tests for active TB

A new policy recommendation released on 20 July by the World Health Organization (WHO) warns against the use of serological (blood) tests to diagnose active tuberculosis.

25 Jul 2011

Elsevier announces availability of iSpeech Audio Reader application

Elsevier, a world leading provider of scientific, technical and medical information products and services, today announced the availability of an audio reader application from iSpeech, provider of cloud-based speech technology and mobile apps, on SciVerse Applications beta.

25 Jul 2011

National Institute of General Medical Sciences now offers range of online products

As the heat index rises, one thing remains at zero—the cost of the engaging and informative educational materials produced by the National Institutes of Health.

25 Jul 2011

New details about how dendritic cells regulate fate of naive T cells

St. Jude Children's Research Hospital scientists show that the molecule serves as a bridge between the two arms of the immune system that provides a new mechanism guiding T cell differentiation.

25 Jul 2011

Report on versatility of nitric oxide in arming hosts against pathogens

A new target for nitric oxide has been revealed in studies of how it inhibits the growth of Salmonella. This bacterium is a common cause of food-poisoning.

25 Jul 2011

Specific yeast protein can promote spontaneous prion formation

It's a chicken and egg question. Where do the infectious protein particles called prions come from? Essentially clumps of misfolded proteins, prions cause neurodegenerative disorders, such as mad cow/Creutzfeld-Jakob disease, in humans and animals.

25 Jul 2011

New method for detecting breast cancer at 'stage 0'

RNL Natural Co., Ltd, a leading biotech company specialized in adult stem cell therapeutics affiliated with RNL BIO Co., Ltd., introduced on June 22, 2011 a new method of detecting breast cancer as early as at 'stage 0' through breath VOCs.

25 Jul 2011

Strategies toxins use to invade human host cells

Toxins produced by plants and bacteria pose a significant threat to humans, as emphasized by the recent effects of cucumber-borne Shiga toxin in Germany. Now, new research published on July 21st by the Cell Press journal Developmental Cell provides a clearer view of the combination of similar and divergent strategies that different toxins use to invade a human host cell.

22 Jul 2011

Sigma Life Science releases breast cancer-specific knockout and knockin cell lines for drug research

Sigma Life Science, the innovative biological products and services research business of Sigma-Aldrich, today announced the expansion of its CompoZr® Oncology Disease Model portfolio with the release of the first in its collection of breast cancer-specific knockout and knockin cell lines for drug discovery and research.

22 Jul 2011

State news: Florida effort could cost consumers $60 million in rebates

The JMH Health Plan, the insurance wing of the Jackson Health System, has become a huge money-loser that must be fixed quickly, board members were told Thursday. So far this year, the plan has lost $30.4 million — almost half of the $71.7 million that Jackson Health System has lost for the entire fiscal year.

22 Jul 2011

SG Austria acquisition benefits Nuvilex with $1.5M in grant funding

Nuvilex, Inc. announced today that as part of its acquisition of SG Austria, Nuvilex will benefit from grant funding previously awarded to SG Austria for its live-cell encapsulation activities and other projects. The total grant funding awarded to SG Austria is approximately $1.5 million.

22 Jul 2011

Myelin regulates key protein involved in sending long-distance signals

The development of a new cell-culture system that mimics how specific nerve cell fibers in the brain become coated with protective myelin opens up new avenues of research about multiple sclerosis. Initial findings suggest that myelin regulates a key protein involved in sending long-distance signals.

22 Jul 2011

Researchers dissociate beneficial and detrimental impacts of maternal regulatory T cells

A normal but concerning consequence of pregnancy is the fact that pregnant women are more susceptible to infection. University of Minnesota Medical School researchers have identified the underlying mechanisms for this physiologic immune suppression that may lead to new therapies to help ward off infections during pregnancy.

22 Jul 2011

Advancements in use of zinc finger nucleases to produce genetically modified pigs

Sangamo BioSciences, Inc. announced the publication of a study demonstrating the use of zinc finger nucleases (ZFNs) to produce genetically modified pigs. The study, which was published in the Proceedings of the National Academy of Sciences (PNAS), represents a significant advancement in the development of improved, less immunogenic animal tissue as a source for transplant into humans.

22 Jul 2011

Health Canada approves SPRYCEL as first-line treatment for life-threatening blood cancer

Canadians newly diagnosed with a life-threatening blood cancer, chronic myeloid leukemia (CML) in chronic phase, now have a new treatment option available to them. Health Canada has granted a notice of compliance with conditions for SPRYCEL (dasatinib) as first-line treatment in patients with chronic phase CML.

22 Jul 2011

Humans' desire to kill rats has only made them stronger

Over millennia, mice have thrived despite humanity's efforts to keep them at bay. A Rice University scientist argues some mice have found two ways to achieve a single goal -- resistance to common poison.

22 Jul 2011

Scientists identify bacterial attack pathway

When competing for food and resources, bacteria employ elaborate strategies to keep rival cells at bay. Scientists have now identified a pathway that allows disease-causing bacteria to attack other bacterial cells by breaking down their cell wall.

22 Jul 2011