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Regulus Therapeutics to host educational webinar about microRNA biology

Regulus Therapeutics Inc., founded by Alnylam Pharmaceuticals, Inc., and Isis Pharmaceuticals, Inc., unveiled plans for an educational webinar about microRNA biology that will highlight several recent exciting discoveries in the field and showcase the therapeutic strategies based on microRNA.

10 Dec 2009

Researchers investigate bone pathology

The best way to prevent a fracture is to stop bones from reaching the point where they are prone to breaking, but understanding the process of how bones form and mature has been challenging. Now researchers at the University of Houston department of health and human performance have created a process that grows real human bone in tissue culture, which can be used to investigate how bones form and grow.

10 Dec 2009

German researchers study target-oriented methods for children with brain tumor

Brain tumors are the primary cause of cancer mortality in children. Even if a cure is possible, young patients often suffer tremendously from the stressful treatment which can be harmful to the developing brain.

10 Dec 2009

CPRIT awards $2 million grant to study prostate cancer

The Cancer Prevention and Research Institute of Texas (CPRIT) has awarded its initial grant for a First-Time, Tenure Track Faculty Member to the University of Texas Southwestern Medical Center in Dallas.

10 Dec 2009

Genetic variations in Sonic Hedgehog pathway associated with response to standard immunotherapy

Genetic variations in the Sonic Hedgehog pathway increase the likelihood of recurrence, reduce survival time and limit response to therapy for people with non-muscle invasive bladder cancer, scientists from The University of Texas M. D. Anderson Cancer Center reported today at the American Association for Cancer Research Frontiers in Cancer Prevention Research Conference.

10 Dec 2009

Rituxan improves patients with previously untreated CLL, shows Phase III study CLL8

Roche announced today at the 51st Meeting of the American Society of Hematology (ASH) in New Orleans, LA (USA) that the pivotal Phase III study CLL8 showed that patients with previously-untreated chronic lymphocytic leukemia (CLL) survived their disease longer when treated with Rituxan (rituximab) compared to chemotherapy alone.

10 Dec 2009

Dermal stem cells may be useful for treating diabetic ulcers and neurological disorders

Scientists have discovered a new type of stem cell in the skin that acts surprisingly like certain stem cells found in embryos: both can generate fat, bone, cartilage, and even nerve cells.

10 Dec 2009

EC grants orphan drug designation for MP4CO for treating sickle cell disease

Sangart, Inc., a global biopharmaceutical company dedicated to developing life-saving medicines specifically designed to enhance the perfusion and oxygenation of ischemic (oxygen deprived) tissues through targeted oxygen and other gas delivery, today announced that the European Commission (EC) has granted orphan medicinal product designation for MP4CO for the treatment of sickle cell disease.

10 Dec 2009

Initiation of dose-finding study to evaluate safety and efficacy of MP4OX treatment

Sangart, Inc., a global biopharmaceutical company dedicated to developing life-saving medicines specifically designed to enhance the perfusion and oxygenation of ischemic (oxygen deprived) tissues through targeted oxygen delivery, today announced the initiation of a dose-finding study designed to evaluate the safety and efficacy of MP4OX treatment plus standard of care in severely injured trauma patients with lactic acidosis due to hemorrhagic shock.

10 Dec 2009

Robarts researcher identifies protein which regulates cell suicide

When cells experience DNA damage, they'll try to repair it. But if that fails, the damaged cells are supposed to self-destruct, a process called apoptosis. A cancer researcher at Robarts Research Institute at The University of Western Ontario has identified a protein that regulates apoptosis, a new discovery which has implications for both the diagnosis and treatment of cancer. Caroline Schild-Poulter's findings are now published online in the journal Molecular Cancer Research.

10 Dec 2009

New protein discovery may serve as potential marker of drug addiction

Scientists are adding additional brush strokes to the revolutionary new image now emerging for star-shaped cells called astrocytes in the brain and spinal cord. Their report, which suggests a key role for astrocytes in morphine's ability to relieve pain and cause addiction, appears online in ACS' Journal of Proteome Research, a monthly publication.

10 Dec 2009

Updated NCCN Guidelines include maintenance therapy for patients with metastatic disease

The National Comprehensive Cancer Network (NCCN) recently updated the NCCN Guidelines for Non-Small Cell Lung Cancer (NSCLC) to incorporate a new section about maintenance therapy, a number of new indications for specific therapies for advanced NSCLC, and the recently revised staging system for lung cancer.

10 Dec 2009

New study suggests mercury-based dental fillings may be less toxic than previously thought

A new study on the surface chemistry of silver-colored, mercury-based dental fillings suggests that the surface forms of mercury may be less toxic than previously thought. It appears online in ACS' journal Chemical Research in Toxicology.

10 Dec 2009

JMC receives NIH grant to establish center of excellence for autoimmune diseases

The Department of Neurology at Jefferson Medical College (JMC) of Thomas Jefferson University has been awarded a multi-million dollar grant from the National Institutes of Health (NIH) for the creation of a center of excellence to study autoimmune diseases from basic science research to its translation into clinical applications.

10 Dec 2009

New research suggests cancer drug may also help patients suffering from asthma

Scientists at the University of Edinburgh found that the drug - R-Roscovitine - helps to kill certain immune cells which can exacerbate symptoms associated with asthma.

10 Dec 2009

Preliminary study shows 'mini' stem cell transplantation may safely reverse severe sickle cell disease

Results of a preliminary study by scientists at the National Institutes of Health and Johns Hopkins show that "mini" stem cell transplantation may safely reverse severe sickle cell disease in adults.

9 Dec 2009

RegeneRx Biopharmaceuticals completes Phase I trial evaluating systemic administration of RGN-352

REGENERX BIOPHARMACEUTICALS, INC. announced today that it has completed and analyzed the safety data from its double-blind, placebo controlled Phase I clinical trial evaluating the systemic administration of RGN-352. The trial included testing of a single escalating intravenous dose of the drug candidate on forty healthy volunteers in Phase IA and, subsequently, over a fourteen-day treatment period on forty volunteers in Phase IB.

9 Dec 2009

CORD:USE Cord Blood Bank awarded contract to supply blood units for the NCBI

CORD:USE Cord Blood Bank is proud to announce that the Health Resources and Services Administration (HRSA) of the U.S. Department of Health and Human Services has awarded CORD:USE Cord Blood Bank a three-year, multi-million dollar contract to expand the supply of cord blood units for the National Cord Blood Inventory (NCBI).

9 Dec 2009

Newly created line of skin care products based on ISCO’s proprietary Parthenogenic Stem Cells

Lifeline Skin Care, Inc, a wholly owned subsidiary of International Stem Cell Corporation, announced today that it has retained the services of a highly experienced expert in the skin care industry, Raulee Marcus, to help design a marketing program for its newly created line of skin care products based on ISCO’s proprietary Parthenogenic Stem Cells.

9 Dec 2009

Protalix Biotherapeutics completes NDA submission for taliglucerase alfa

Protalix Biotherapeutics, Inc. today announced the completion of its New Drug Application (NDA) submission with the U.S. Food and Drug Administration (FDA) for taliglucerase alfa, a plant-cell expressed form of glucocerebrosidase (GCD) for the potential treatment of Gaucher’s disease.

9 Dec 2009

Cell News and Research

Regulus Therapeutics to host educational webinar about microRNA biology

Researchers investigate bone pathology

German researchers study target-oriented methods for children with brain tumor

CPRIT awards $2 million grant to study prostate cancer

Genetic variations in Sonic Hedgehog pathway associated with response to standard immunotherapy

Rituxan improves patients with previously untreated CLL, shows Phase III study CLL8

Dermal stem cells may be useful for treating diabetic ulcers and neurological disorders

EC grants orphan drug designation for MP4CO for treating sickle cell disease

Initiation of dose-finding study to evaluate safety and efficacy of MP4OX treatment

Robarts researcher identifies protein which regulates cell suicide

New protein discovery may serve as potential marker of drug addiction

Updated NCCN Guidelines include maintenance therapy for patients with metastatic disease

New study suggests mercury-based dental fillings may be less toxic than previously thought

JMC receives NIH grant to establish center of excellence for autoimmune diseases

New research suggests cancer drug may also help patients suffering from asthma

Preliminary study shows 'mini' stem cell transplantation may safely reverse severe sickle cell disease

RegeneRx Biopharmaceuticals completes Phase I trial evaluating systemic administration of RGN-352

CORD:USE Cord Blood Bank awarded contract to supply blood units for the NCBI

Newly created line of skin care products based on ISCO’s proprietary Parthenogenic Stem Cells

Protalix Biotherapeutics completes NDA submission for taliglucerase alfa

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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