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Researchers elucidate how gene mutation mechanism causes autism

Researchers show how mutations of gene transcription and chromatin regulation-related genes cause autism.

9 Apr 2024

The complex relationship between obesity and male reproductive function

Authors have analyzed current evidence on the impact of obesity on the male reproduction system.

9 Apr 2024

Rogue immune cell found to cause poor antibody responses in chronic viral infections

Australian researchers have discovered a previously unknown rogue immune cell that can cause poor antibody responses in chronic viral infections.

9 Apr 2024

Fluent BioSciences awarded NIH SBIR grant to commercialize low-cost million-cell transcriptome profiling kits

Fluent BioSciences, a cutting-edge life sciences company leading the charge in revolutionizing single-cell analysis through simple, cost-effective, and highly scalable single-cell RNA sequencing solutions is thrilled to announce the award of an NIH Small Business Innovation Research (SBIR) Phase II grant, funded by the National Institute of General Medical Sciences (NIGMS, 2 R44 GM137648).

From Fluent Biosciences 9 Apr 2024

Chronic low-level inflammation may be a contributor to both depression and heart disease

Coronary artery disease and major depression may be genetically linked via inflammatory pathways to an increased risk for cardiomyopathy, a degenerative heart muscle disease, researchers at Vanderbilt University Medical Center and Massachusetts General Hospital have found.

8 Apr 2024

Novel signaling pathway identified in lysosome damage response

Lysosomes are surrounded by a lipid bilayer that separates the acidic environment and the digestive enzymes of the organelle from the cytoplasm.

8 Apr 2024

Novel therapeutic approach identified for overcoming resistance in B-cell leukemia

Despite having an overall survival rate of 94%, B-cell acute lymphoblastic leukemia (B-ALL), the most common childhood cancer, can prove challenging to treat, with survival among relapsed or resistant cases falling between 30-50%.

8 Apr 2024

NeuM technology revolutionizes neuron labeling for neurodegenerative disease research

Alzheimer's disease and Parkinson's disease, along with stroke, are among the top three neurodegenerative disorders, characterized by the malfunction and progressive degeneration of neurons, the nerve cells.

8 Apr 2024

Expanding research and clinical options for children with cancer

In this interview, Dr. Church, the Molecular and Pediatric Pathologist at Boston Children's Hospital, talks to NewsMedical about their work in pediatric oncology, and the need to expand research and clinical options for children with cancer.

From Tecan 8 Apr 2024

Pioneering vaccine strategy promises to outmaneuver antimicrobial resistance

Study introduces Reverse Vaccine Development as a strategic approach to identify correlates of protection early in vaccine development against antimicrobial-resistant pathogens, aiming to mitigate risks such as significant phase-III clinical trial failures.

7 Apr 2024

Wound warriors: How microbes influence healing and infection risks

Study explores how wound microbiota affect skin repair and infection risk by altering host immune responses, underscoring the complexity of microbial interactions in wound healing.

7 Apr 2024

Childhood obesity not linked to adult skin cancer risk, study says

Study leverages a Mendelian randomization approach to explore if childhood obesity genetically predisposes individuals to adult skin cancer, finding no significant correlation.

7 Apr 2024

Regular late-life exercise has a beneficial impact on DNA damage and telomere dysfunction

Regular aerobic exercise later in life prevents genomic instability characterized by DNA damage and telomere dysfunction, according to a study from the Department of Internal Medicine at the University of Utah.

7 Apr 2024

Researchers develop first genetic maps for disease-linked DNA repeats

A research team led by the University of California, Irvine has built the first genetic reference maps for short lengths of DNA repeated multiple times which are known to cause more than 50 lethal human diseases, including amyotrophic lateral sclerosis, Huntington's disease and multiple cancers.

5 Apr 2024

New ovarian atlas paves the way for extended fertility and hormone restoration

A new "atlas" of the human ovary provides insights that could lead to treatments restoring ovarian hormone production and the ability to have biologically related children, according to University of Michigan engineers.

5 Apr 2024

Mitochondrial fusion critical for adult neurogenesis and brain circuit refinement

Nerve cells (neurons) are amongst the most complex cell types in our body. They achieve this complexity during development by extending ramified branches called dendrites and axons and establishing thousands of synapses to form intricate networks.

5 Apr 2024

New method to evaluate enzymes opens path to ferroptosis-targeting cancer drugs

New research could pave the way to develop cancer drugs targeting an enzyme that inhibits ferroptosis, a type of cell death.

5 Apr 2024

Modeled human embryo produces a membrane that surrounds the developing embryo

A MedUni Vienna study team led by geneticist Markus Hengstschläger has used a stem cell model to model the earliest stages of embryonic development and to characterize the membrane that surrounds the embryo, conferring shape and stability.

5 Apr 2024

Neuroscientists identify age-defying RNAs in the brain

Certain RNA molecules in the nerve cells in the brain last a life time without being renewed. Neuroscientists from Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) have now demonstrated that this is the case together with researchers from Germany, Austria and the USA.

5 Apr 2024

Human neuron model identifies potential therapeutic targets for Alzheimer's disease

Weill Cornell Medicine scientists have developed an innovative human neuron model that robustly simulates the spread of tau protein aggregates in the brain-;a process that drives cognitive decline in Alzheimer's disease and frontotemporal dementia.

5 Apr 2024

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Cell News and Research

Researchers elucidate how gene mutation mechanism causes autism

The complex relationship between obesity and male reproductive function

Rogue immune cell found to cause poor antibody responses in chronic viral infections

Fluent BioSciences awarded NIH SBIR grant to commercialize low-cost million-cell transcriptome profiling kits

Chronic low-level inflammation may be a contributor to both depression and heart disease

Novel signaling pathway identified in lysosome damage response

Novel therapeutic approach identified for overcoming resistance in B-cell leukemia

NeuM technology revolutionizes neuron labeling for neurodegenerative disease research

Expanding research and clinical options for children with cancer

Pioneering vaccine strategy promises to outmaneuver antimicrobial resistance

Wound warriors: How microbes influence healing and infection risks

Childhood obesity not linked to adult skin cancer risk, study says

Regular late-life exercise has a beneficial impact on DNA damage and telomere dysfunction

Researchers develop first genetic maps for disease-linked DNA repeats

New ovarian atlas paves the way for extended fertility and hormone restoration

Mitochondrial fusion critical for adult neurogenesis and brain circuit refinement

New method to evaluate enzymes opens path to ferroptosis-targeting cancer drugs

Modeled human embryo produces a membrane that surrounds the developing embryo

Neuroscientists identify age-defying RNAs in the brain

Human neuron model identifies potential therapeutic targets for Alzheimer's disease

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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