Cell Adhesion News and Research

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Two-test combination accurately identifies benign pancreatic lesions

When performed in tandem, two molecular biology laboratory tests distinguish, with near certainty, pancreatic lesions that mimic early signs of cancer but are completely benign.

23 Jun 2017

Impaired effects of insulin can increase cancer risk, shows study

Over the decades, scientists have repeatedly shown that patients with increased levels of the hormone insulin in their blood can experience increased risks of cancer. Surprisingly, however, Joslin Diabetes Center researchers now have discovered that impaired effects of insulin also can boost these risks.

3 May 2017

JAX professor receives grant from National Eye Institute to study diseases of retinal pigment epithelium

The National Eye Institute has awarded Jackson Laboratory Professor Patsy Nishina, Ph.D., and Associate Professor Gregory Carter, Ph.D., a four-year grant totaling $2,414,304 to study diseases of the retinal pigment epithelium (RPE), with the goal of identifying druggable targets for age-related macular degeneration and other heritable retinal diseases.

11 Apr 2017

Researchers pinpoint Jumonji protein as key to Ewing's Sarcoma spread

By the time Ewing's Sarcoma is diagnosed, primarily in teens and young adults, it has often spread from its primary site to other parts of the body, making it difficult to treat.

24 Mar 2017

Researchers discover unexpected link between brain development and tumor invasion

Researchers from Turku Centre for Biotechnology have observed that a protein called SHANK prevents the spread of breast cancer cells to the surrounding tissue.

9 Mar 2017

TSRI scientists discover how key protein establishes proper vision

Scientists from the Florida campus of The Scripps Research Institute have discovered how a protein called α2δ4 establishes proper vision.

6 Mar 2017

Drugs that target tissue stiffness could potentially prevent cancer metastasis

In order for cancer to spread, malignant cells must break away from a tumor and through the tough netting of extracellular matrix, or ECM, that surrounds it. To fit through the holes in this net, those cancerous cells must elongate into a torpedo-like shape.

22 Feb 2017

Scientists aim to create better contact lenses that maximize comfort, alleviate dry eye symptoms

Symptoms of dry eye syndrome -- dry, red, itchy, gritty, sore eyes -- are more common among contact lens wearers. But relief may be on the horizon, thanks to a group of Stanford University researchers and their work exploring the mechanical interactions between the eye surface, the cornea and contact lenses.

14 Feb 2017

Researcher develops new method to accurately identify elusive molecules

Among the most important molecules in the living world are sugars or carbohydrates, which play a vital role in life processes. Sugars provide the main source of fuel for the body, protect muscles from damage and contribute to the immune response.

21 Dec 2016

Researchers use CRISPR-based genetic screening to identify three promising HIV treatment targets

Investigators from Whitehead Institute, the Ragon Institute of MGH, MIT and Harvard and the Broad Institute of MIT and Harvard have used CRISPR-Cas9 gene-editing technology to identify three promising new targets for treatment of HIV infection.

20 Dec 2016

Neu5Gc common in red meat increases risk of tumor formation

Neu5Gc, a non-human sialic acid sugar molecule common in red meat that increases the risk of tumor formation in humans, is also prevalent in pig organs, with concentrations increasing as the organs are cooked, a study by researchers from the UC Davis School of Medicine and Xiamen University School of Medicine has found.

19 Oct 2016

Scientists discover new receptors for stomach bacterium Helicobacter pylori

A research group led by Prof. Markus Gerhard of the Technical University of Munich and Assistant Professor Dr. Bernhard B. Singer of the Institute for Anatomy at the Faculty of Medicine of the University of Duisburg-Essen at Essen University Medical Centre has discovered a completely new approach to preventing or treating infections with this bacterium as well as secondary complications.

19 Oct 2016

Researchers discover new approach to preventing H. pylori linked to stomach infections

Researchers have discovered a new approach to preventing or treating a stomach bacterium associated with an increased risk of stomach cancer as well as gastritis and duodenal ulcers.

18 Oct 2016

Chemotherapy leads to drug-resistance in bladder cancer patients

Chemotherapy is indicated as the first line of treatment for advanced bladder cancer. New research by Weill Cornell Medicine and University of Trento scientists shows that while chemotherapy kills the most common type of bladder cancer, urothelial cancer, chemotherapy also shapes the genetic evolution of remaining urothelial cancer cell clones to become drug-resistant.

18 Oct 2016

Stressful event appears to erase benefits linked to healthy fat choices

The type of fat you eat matters, but a new study suggests that the benefits of good fats vanish when stress enters the picture.

20 Sep 2016

New mouse model helps identify potential drug target for hard-to-treat social aspects of ASD

A study of a new mouse model identifies a drug target that has the potential to increase social interaction in individuals with some forms of autism spectrum disorder (ASD), according to researchers in the Perelman School of Medicine at the University of Pennsylvania. The team published their work in Biological Psychiatry.

9 Sep 2016

Shire’s Xiidra receives FDA approval for treating dry eye disease in adult patients

Shire plc announces that the U.S. Food and Drug Administration has approved Xiidra (lifitegrast ophthalmic solution) 5%, a twice-daily eye drop solution indicated for the treatment of the signs and symptoms of dry eye disease in adult patients.

12 Jul 2016

Virtual tissue technology helps identify new drug target to combat polycystic kidney disease

Using virtual tissue technology, researchers at Indiana University have identified a potential new drug target in the fight against polycystic kidney disease, an illness with no effective FDA-approved treatment that affects 200,000 people per year in the United States.

28 Jun 2016

Already-approved drugs can fight apoptosis evasion in cancer

Cancer cells don't die when they're supposed to. Animal and human bodies follow an orderly process of birthing new cells and killing old ones. But cancer cells escape programmed cell death, called apoptosis, and multiply uncontrollably.

15 Jun 2016

New research uncovers vital role of DHHC9 enzyme in brain circuit development

Research by Dr. Shernaz Bamji, from the University of British Columbia, uncovers the mechanism of action of an enzyme called DHHC9 in the normal development and function of neural networks in the brain.

31 May 2016