Cell Adhesion News and Research

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Blood proteins could be potential targets for future drugs to slow aging process

Two blood proteins have been shown by scientists to influence how long and healthy a life we live, research suggests.

24 Jan 2022

Novel mechanism linking intercellular adhesion molecule with genetic skin diseases discovered

Northwestern Medicine investigators have discovered a novel mechanism linking an intercellular adhesion molecule with genetic inflammatory skin diseases, according to findings published in the Journal of Clinical Investigation.

11 Jan 2022

Host kinase identified as an inhibition target for SARS-CoV-2

In this experiment, the chemical probe SGC-CK2-1 inhibited virus replication at nanomolar concentration, showing a highly selective effect on the kinase.

6 Jan 2022

Polyrotaxane-based biomaterials enhance the connection between epithelial cells

The field of tissue engineering is constantly exploring the possibility of using different properties of various biomaterials to achieve tissue regeneration.

21 Dec 2021

Engineering of brain-mimetic injectable hydrogel scaffolds with self-healing properties

A team of scientists bioengineered a physiologically relevant, brain mimetic 3D scaffold for culturing neuronal cells.

15 Dec 2021

Researchers discover mechanism for congenital disorders of glycosylation

Greenwood Genetic Center researchers are reporting the discovery of a mechanism that contributes to the tissue phenotypes seen in PMM2-CDG, the most common of the congenital disorders of glycosylation (CDGs).

8 Dec 2021

Nanocomputing agent controls the function of protein involved in cell movement, cancer metastasis

The creation of nanoscale computers for use in precision health care has long been a dream of many scientists and health care providers.

16 Nov 2021

Generating Cell Repellent Surfaces in Microfluidic Devices

AMSBIO report that researchers from the Medical University of Vienna (Austria), have used Lipidure® - CM5206 to coat channels in their novel microfluidic devices, to prevent cell adhesion.

From AMS Biotechnology 15 Oct 2021

CXCR6/CXCL16 axis has significant role in the immuno-pathogenesis of severe COVID-19

In a study published on the preprint server medRxiv*, scientists studying the SARS-CoV-2 genome have identified a region linked with the disease severity.

16 Sep 2021

JunD promotes epithelial-to-mesenchymal transition by association with NEAT1 lncRNA

Oncotarget published "JunD accentuates arecoline-induced disruption of tight junctions and promotes epithelial-to-mesenchymal transition by association with NEAT1 lncRNA" which reported that the effects of low and high concentrations of arecoline on the stability of tight junctions and EMT induction were studied.

3 Sep 2021

The influence of COVID-19 on platelet activation and aggregation

In a paper recently uploaded to the bioRxiv* preprint server, humanized ACE2 mice are infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and platelets are subsequently isolated from the blood for quantitative proteomic analysis.

26 Aug 2021

Study uncovers molecular mechanisms that promote cell-to-cell adhesion and communication

A study led by Northwestern Medicine investigators has identified the molecular mechanisms within protein complexes that promote cell-to-cell adhesion and communication, according to findings published in the Proceedings of the National Academy of Sciences.

11 Aug 2021

HKU research team sheds critical insight on what causes abnormal embryo elongation

Fetal abnormalities are of concern to all prospective parents, and many of these problems originate from abnormalities in the development of the embryo particularly during its elongation and division.

10 Aug 2021

Large nanodiscs simulate viral entry into host cells

In a paper recently uploaded to the journal Frontiers in Biotechnology by Padmanabha Das et al. (June 12th, 2020), a method of producing significantly larger homogenous nanodiscs up to 90 nm in diameter is described, and the advantages and applications of such nanodiscs are explored: better replicating the actual curvature and membrane symmetry of a real cell membrane, and allowing much larger or multiple membrane proteins to be loaded simultaneously.

30 Jul 2021

Cell Adhesion News and Research

Blood proteins could be potential targets for future drugs to slow aging process

Novel mechanism linking intercellular adhesion molecule with genetic skin diseases discovered

Host kinase identified as an inhibition target for SARS-CoV-2

Polyrotaxane-based biomaterials enhance the connection between epithelial cells

Engineering of brain-mimetic injectable hydrogel scaffolds with self-healing properties

Researchers discover mechanism for congenital disorders of glycosylation

Nanocomputing agent controls the function of protein involved in cell movement, cancer metastasis

Generating Cell Repellent Surfaces in Microfluidic Devices

CXCR6/CXCL16 axis has significant role in the immuno-pathogenesis of severe COVID-19

JunD promotes epithelial-to-mesenchymal transition by association with NEAT1 lncRNA

The influence of COVID-19 on platelet activation and aggregation

Study uncovers molecular mechanisms that promote cell-to-cell adhesion and communication

HKU research team sheds critical insight on what causes abnormal embryo elongation

Large nanodiscs simulate viral entry into host cells

Activation of integrins by SARS-CoV-2 may be key to infection

Study finds sex differences in astrocyte-mediated synaptic connectivity during brain development

Combination of investigational therapeutic and chemotherapy shows promise for AML treatment

Research sheds light on a new mechanism for inhibitory synapse specificity in the cortex

Targeting lung inflammation with cell membrane-based dexamethasone nanodelivery platform

New mathematical model helps simulate progression of age-related macular degeneration

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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