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How Candida albicans transforms from its normally benign form into life-threatening form

Researchers at the Agency for Science, Technology and Research's (A*STAR) Institute of Molecular and Cell Biology (IMCB) have discovered new molecular mechanisms that provide a more detailed understanding of how the normally benign Dr. Jekyll-like fungus known as Candida albicans transforms into a serious and often life-threatening Mr. Hyde-like form.

4 Oct 2007

New findings on cholesterol metabolism in the brain and Alzheimer's disease

Although the causes of Alzheimer's disease are not completely understood, amyloid-beta (A-beta) is widely considered a likely culprit - the "sticky" protein clumps into plaques thought to harm brain cells.

4 Oct 2007

The origin of mammalian network of lymphatic vessels

Investigators at St. Jude Children's Research Hospital settled a century-old debate on the origin of the mammalian lymphatic vasculature - the network of vessels and capillaries critical to various essential housekeeping functions in the body.

4 Oct 2007

Leptin plays a major role in islet cell growth and insulin secretion

A new Joslin-led study has shown that leptin, a hormone known mainly for regulating appetite control and energy metabolism, plays a major role in islet cell growth and insulin secretion.

2 Oct 2007

Gene that lowers cell stress could protect against Parkinson's disease

The discovery of a relationship between two cell enzymes and their role in keeping the cell's energy generating machinery working smoothly could provide a new target for development of therapies for Parkinson's disease (PD).

2 Oct 2007

Gene that lowers cell stress could protect against Parkinson’s disease

1 Oct 2007

Variation in drug responses can be analyzed by studying simpler organisms like plants

While prescription medications work successfully to cure an ailment in some people, in others the same dose of the same drug can cause an adverse reaction or no response at all.

27 Sep 2007

Discovery of structure in malaria with potential for a vaccine target

Researchers at the Swedish medical university Karolinska Institutet (KI) and the Swedish Institute for Infectious Disease Control (SMI) have identified the biochemical mechanism behind the adhesive protein that give rise to particularly serious malaria in children.

25 Sep 2007

Breast cancer death rate continues to drop

A report from the American Cancer Society finds the breast cancer death rate in the United States continues to drop more than two percent per year, a trend that began in 1990 and is credited to progress in early detection and treatment.

25 Sep 2007

Scientists capture first optical images of carbon nanotubes inside a living organism

Using fruit flies, the researchers confirmed that a technique developed at Rice -- near-infrared fluorescent imaging -- was capable of detecting DNA-sized nanotubes inside living fruit flies.

25 Sep 2007

Coronary heart disease: Spotting the culprit(s) is the way towards prevention

A Public Lecture at Bristol University to rise awareness on a socially relevant still belittled disease

24 Sep 2007

Black men do not have more aggressive prostate cancer

A University of Minnesota study of prostate cancer tumors from Caucasian and African-American men has shown no evidence that the cancer is more aggressive in black men.

18 Sep 2007

New understanding of gene mutation responsible for fragile X syndrome

Scientists have discovered how the gene mutation responsible for fragile X syndrome - the most common inherited form of mental retardation - alters the way brain cells communicate.

18 Sep 2007

Zebrafish shed light on human mitochondrial diseases

Zebrafish can now be used to study COX deficiencies in humans, a discovery that gives scientists an unprecedented window to view the earliest stages of mitochondrial impairments that lead to potentially fatal metabolic disorders, according to researchers at the University of Oregon.

13 Sep 2007

Proteins Nox1 and Nox2 play important role in amyotrophic lateral sclerosis

University of Iowa researchers investigating the basic biology of cell signaling have made a discovery that may have therapeutic implications for amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases.

13 Sep 2007

New insights into retinal growth

Peering at microscopic changes within the retina, scientists in the Department of Ophthalmology at Weill Cornell Medical College in New York City, have discovered a key mechanism driving eye health and eye disease.

12 Sep 2007

Embryonic stem cell strategy advanced with UCSF finding

UCSF scientists are reporting what they say is a significant improvement in the technique for genetically reprogramming mouse cells to their embryonic state, a process that transforms the cells, in essence, into embryonic stem cells.

12 Sep 2007

Clearer picture of how a dividing cell rebuilds the nuclear envelope

Just how a dividing cell rebuilds the nuclear envelope, the protective, functional wrapping that encases both the original and newly copied genetic material, has been a source of controversy for the last 20 years.

10 Sep 2007

Myoendothelial cells identified as new human source of stem cells with potential to repair muscle

For the first time, scientists at Children's Hospital of Pittsburgh of UPMC have discovered a unique population of adult stem cells derived from human muscle that could be used to treat muscle injuries and diseases such as heart attack and muscular dystrophy.

5 Sep 2007

Study identifies osteopontin as a key player in the body's immune response to chronic stress

Osteopontin (OPN), a protein molecule involved in many different cellular processes, plays a significant role in immune deficiency and organ atrophy following chronic physiological stress, resulting in increased susceptibility to illness.

4 Sep 2007