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Female sex hormones play significant role in Alzheimer's disease

Alzheimer's disease disproportionately affects women, who represent about two-thirds of those diagnosed with the late-onset type of the disease.

17 Oct 2023

Researchers study how cells adapt to stressful and complex environments

Imagine the life of a yeast cell, floating around the kitchen in a spore that eventually lands on a bowl of grapes. Life is good: food for days, at least until someone notices the rotting fruit and throws them out.

16 Oct 2023

TTUHSC receives nearly $2.3 million in CPRIT grants to support cancer research

The Cancer Prevention and Research Institute of Texas (CPRIT) recently awarded grants to four researchers from the Texas Tech University Health Sciences Center (TTUHSC).

12 Oct 2023

New drug molecule restores lost nerve-muscle connections, enhances strength

A small molecule previously shown to enhance strength in injured or old laboratory mice does so by restoring lost connections between nerves and muscle fibers, Stanford Medicine researchers have found.

11 Oct 2023

Harvard neuroscientist seeks to capture synapse-level connectome data from a mouse brain

The human brain is a tangled highway of wires emanating from nearly 100 billion neurons, all of which communicate across trillions of junctions called synapses. "Depressingly complex," Harvard neuroscientist Jeff Lichtman calls it.

9 Oct 2023

Groundbreaking research may provide hope to better understand and prevent Alzheimer’s disease

As of 2020, approximately 5.8 million Americans suffer from Alzheimer’s disease, but recent groundbreaking research may provide hope to better understand and potentially prevent this devastating condition.

9 Oct 2023

Wildling mice provide insights into how microbes affect allergies

The notion that some level of microbial exposure might reduce our risk of developing allergies has arisen over the last few decades and has been termed the hygiene hypothesis.

29 Sep 2023

Study reveals new insights into how the immune system prevents autoimmunity

Researchers at Stanford University School of Medicine, Yale University School of Medicine, and the Hospital for Special Surgery Research Institute have uncovered new details about how the immune system prevents the production of antibodies that can recognize and damage the body's own, healthy tissues.

29 Sep 2023

Vaxzevria vaccine boosts mucosal immunity in COVID-19 recovered

Study highlights the ability of the Vaxzevria vaccine in inducing robust mucosal antibody responses, especially in COVID-19-recovered individuals, showcasing a notable defense against various SARS-CoV-2 variants. However, it emphasizes the need for booster doses to enhance anti-SARS-CoV-2 mucosal immunity, especially in infection-naïve individuals, to broaden protection against emerging viral variants.

28 Sep 2023

Blocking Notch signaling pathway could reverse age-related bone loss

A cellular signal essential to the development of the skeleton increases during aging to weaken bones, finds a new study in mice.

27 Sep 2023

Arrayed CRISPR Screening for Revolutionizing Target Discovery

In this interview conducted at SLAS EU 2023 in Brussels, Belgium, we spoke to Ulrike Kuenzel, Associate Director in the Functional Genomics department at AstraZeneca about the application of arrayed CRISPR screening for target identification and more.

From Society for Laboratory Automation and Screening (SLAS) 27 Sep 2023

PhenomeX announces the release of SpotLight™ Human Lambda reagent for the Beacon® platform to accelerate cell line development workflows

PhenomeX Inc., a functional cell biology company, is pleased to announce that GSK will present data on the SpotLight™ Human Lambda reagent for the Beacon® platform at the 16th annual Conference on Protein Expression in Animal Cells, which is being held in Sitges, Spain from September 24-28, 2023.

From Bruker Cellular Analysis 25 Sep 2023

Study provides insights into human 8-cell-like cells and early embryonic development

The onset of embryo-specific gene transcription, also known as embryonic genome activation (EGA), is a crucial step in the developmental journey of an organism.

22 Sep 2023

CPRIT awards $2 million to SMU to recruit cancer biology researcher Annika Wylie

The Cancer Prevention and Research Institute of Texas (CPRIT) has awarded $2 million to recruit Annika Wylie to SMU and fund five years of her research, which focuses on the p53 gene, a naturally occurring tumor suppressor.

21 Sep 2023

Study offers new insight into immune cells critical to successful vaccination against SARS-CoV-2

A study has revealed new details about a key population of immune system cells critical to successful vaccination against the pandemic virus, SARS-CoV-2.

21 Sep 2023

University of Arkansas receives $3.1 million NIH award to study pediatric mitochondrial disorders

The Eunice Kennedy Shriver National Institute of Child Health and Human Development awarded $3.1 million to the University of Arkansas to study a spectrum of pediatric mitochondrial disorders caused by mutations in the mitochondria.

20 Sep 2023

Mapping the human body one cell at a time: New study reveals the intricate relationship between cell size and count

A study published in PNAS provides a comprehensive look at the relationship between cell size and count across the human body, drawing from over 1,500 sources and identifying around 400 unique cell types. The research reveals an almost inverse relationship between cell size and count, offering a quantitative framework that could serve as a baseline for understanding cellular composition and function in various applications.

19 Sep 2023

Research demonstrates a double-acting mechanism for fighting triple-negative breast cancer

Zachary Schug, Ph.D., assistant professor in the Molecular and Cellular Oncogenesis Program of the Ellen and Ronald Caplan Cancer Center at The Wistar Institute, has published a new paper in the journal Nature Cancer.

19 Sep 2023

Specialized gut immune cells could be new biomarker for IBD progression

Researchers at the Francis Crick Institute, King's College London and Guy's and St Thomas' NHS Foundation Trust have characterised a specialised type of immune cell, which plays a key role in protecting and repairing the cells in the healthy human gut.

14 Sep 2023

Innovative technique provides unparalleled insight into autism pathology

Does the human brain have an Achilles heel that ultimately leads to Autism? With a revolutionizing novel system that combines brain organoid technology and intricate genetics, researchers can now comprehensively test the effect of multiple mutations in parallel and at a single-cell level within human brain organoids.

13 Sep 2023