Cell Death News and Research

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Researchers identify a novel mechanism connected to the early stages of Alzheimer's disease

Alzheimer's disease (AD) remains one of the most challenging and prevalent neurodegenerative disorders, affecting millions of individuals worldwide.

15 Apr 2024

U-M study reveals potential pathway to reverse lung fibrosis

The most common type of lung fibrosis -; scarring of the lungs -- is idiopathic, meaning of unknown cause.

13 Apr 2024

Researchers create novel drug that can prevent flu-induced lung injury

Infection with the influenza virus leads to lung injury through inflammation over-activation that causes collateral damage to cells required for breathing.

10 Apr 2024

Research identifies how leukemia develops resistance to first line treatments

Relapses in a common form of leukemia may be preventable following new research which has identified how the cancer develops resistance to first line treatments.

9 Apr 2024

The complex relationship between obesity and male reproductive function

Authors have analyzed current evidence on the impact of obesity on the male reproduction system.

9 Apr 2024

Novel signaling pathway identified in lysosome damage response

Lysosomes are surrounded by a lipid bilayer that separates the acidic environment and the digestive enzymes of the organelle from the cytoplasm.

8 Apr 2024

Novel therapeutic approach identified for overcoming resistance in B-cell leukemia

Despite having an overall survival rate of 94%, B-cell acute lymphoblastic leukemia (B-ALL), the most common childhood cancer, can prove challenging to treat, with survival among relapsed or resistant cases falling between 30-50%.

8 Apr 2024

New method to evaluate enzymes opens path to ferroptosis-targeting cancer drugs

New research could pave the way to develop cancer drugs targeting an enzyme that inhibits ferroptosis, a type of cell death.

5 Apr 2024

Therapeutic potential of CD20 x CD3 bispecific antibodies

On Monday, March 25th, 2024, the U.S. FDA declined approval for Regeneron’s Odronextamab for two forms of lymphoma due to concerns over the progress of ongoing confirmatory trials.

From Sino Biological Inc. 5 Apr 2024

Newly discovered cause for asthma sparks hope for treatment

Scientists at King's College London have discovered a new cause for asthma that sparks hope for treatment that could prevent the life-threatening disease.

4 Apr 2024

Using brain organoids to unlock TBI's link to dementia and ALS

A traumatic brain injury (TBI) can quadruple your risk for developing dementia and increase your chances of developing neurodegenerative diseases such as ALS.

4 Apr 2024

Advancing osteosarcoma prognosis with AI-assisted tumor cell density analysis

Researchers at Kyushu University have developed and validated a machine-learning model that can accurately evaluate the density of surviving tumor cells after treatment in pathological images of osteosarcoma-;the most prevalent malignant bone tumor.

2 Apr 2024

Novel antibiotic-infused hydrogel kills bacteria and promotes cell growth

Hydrogels are popular for use in skin ailments and tissue engineering. These polymer-based biocompatible materials are useful for their abilities to retain water, deliver drugs into wounds, and biodegrade.

2 Apr 2024

Researchers decode the evolutionary pathway of regulatory proteins

New research from the University of Wisconsin–Madison decodes the evolutionary pathway of regulatory proteins, the molecules that help control gene expression.

29 Mar 2024

Research highlights health risks posed by 2,6-DHNPs in drinking water

2,6-DHNPs, a group of disinfection byproducts (DBPs), are raising alarm bells for public health. These bad actors in the water world are tougher and more toxic than many other pollutants, making it hard for typical water cleaning methods to get rid of them.

29 Mar 2024

Dartmouth research unlocks extended cell death pathway in aging brain cells

For oligodendrocytes-;the central nervous system cells critical for brain function-;age may not bring wisdom, but it does come with the power to cling to life for much, much longer than scientists knew.

28 Mar 2024

Study reveals trigonelline as a therapeutic agent for mitochondrial dysfunction in aging

Sarcopenia is the age-related decline in skeletal muscle due to the wasting of myofiber.

26 Mar 2024

MUTYH gene mutation linked to increased risk of various solid tumors

A gene associated with colorectal cancer appears to also play a role in the development of other solid tumors, according to a study of over 350,000 patient biopsy samples conducted by researchers at the Johns Hopkins Kimmel Cancer Center, the Johns Hopkins Bloomberg School of Public Health and Foundation Medicine.

25 Mar 2024

Study reveals e-cigarette users with limited smoking history show similar DNA alterations as smokers

A study assessed the effect of tobacco smoking and electronic cigarette (e-cigarettes) use on DNA methylation changes associated with carcinogenesis.

25 Mar 2024

NUS study reveals key mechanisms behind drug resistance in relapsed acute myeloid leukemia

Scientists from the National University of Singapore (NUS) have discovered that the evasion of apoptosis is a key driver of drug resistance in patients with relapsed acute myeloid leukaemia (AML), a type of aggressive blood cancer.

19 Mar 2024