Cell Death News and Research

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U of A researchers discover potential new drug target for MS

Medical researchers at the University of Alberta have discovered a potential new drug target for Multiple Sclerosis that could prevent physical disability associated with the disease, once a new drug is developed.

27 Oct 2011

Wolbachia study reveals novel approaches to control insects transmitting deadly diseases

Researchers at Boston University have made discoveries that provide the foundation towards novel approaches to control insects that transmit deadly diseases such as dengue fever and malaria through their study of the Wolbachia bacteria.

21 Oct 2011

CERT gene silencing makes breast cancer cells more sensitive to drugs

CANCER RESEARCH UK scientists have discovered that switching off a gene called CERT makes breast cancer cells more sensitive to a range of drugs. The research is published in the Journal of Pathology.

21 Oct 2011

Pesticides, pollutants increase risk of spina bifida and anencephaly in rural China

Pesticides and pollutants are related to an alarming 450 percent increase in the risk of spina bifida and anencephaly in rural China, according to scientists at The University of Texas at Austin and Peking University.

20 Oct 2011

Hypertension drugs might reduce occurrence of Alzheimer's

Within the next 20 years it is expected the number of people with Alzheimer's disease (AD) will double from its current figure of half a million to one million. A new study has looked at whether certain types of drugs used to treat high blood pressure, also called hypertension, might have beneficial effects in reducing the number of new cases of Alzheimer's disease each year.

18 Oct 2011

Stopping necroptosis in keratinocytes prevents skin inflammation

The outer layer of the skin, called the epidermis, forms a critical physical and immunological wall that serves as the body's first line of defense against potentially harmful microorganisms. Most of the epidermis consists of cells called keratinocytes that build a mechanical barrier but also perform immune functions.

14 Oct 2011

NCCN Oncology Research Program wins two GSK grants

The National Comprehensive Cancer Network Oncology Research Program (ORP) has been awarded $4 million in the form of two research grants from GlaxoSmithKline (GSK) to develop studies to scientifically evaluate and define GSK2118436, a BRAF inhibitor, and GSK1120212, a MEK1 and MEK2 inhibitor. Previous research has indicated that BRAF mutations are strong targets for therapies in the treatment of advanced melanoma.

12 Oct 2011

Scientists identify first DNA faults linked to melanoma

Cancer Research UK scientists have discovered the first DNA faults linked to melanoma - the deadliest skin cancer - that are not related to hair, skin or eye colour, according to research published in Nature Genetics today.

10 Oct 2011

Study identifies three new chromosomal regions implicated in susceptibility to melanoma

The genomic analysis technologies enable the study of genetic factors related to numerous diseases. In few areas this researches brought such a big and useful volume of information as in the case of melanoma.

10 Oct 2011

Less toxic amounts of chemotherapy medicine slows tumor growth: Scientists

University of Georgia scientists have found that smaller, less toxic amounts of chemotherapy medicine given frequently to mice with human prostate cancer noticeably slowed tumor growth.

1 Oct 2011

Researchers determine structure of RIG-I protein linked with viral infections

Researchers at Rutgers and UMDNJ-Robert Wood Johnson Medical School have determined the structure of a protein that is the first line of defense in fighting viral infections including influenza, hepatitis C, West Nile, rabies, and measles.

30 Sep 2011

Plausible way to circumvent drug resistance in breast cancer cells

Breast cancer cells that mutate to resist drug treatment survive by establishing tiny pumps on their surface that reject the drugs as they penetrate the cell membrane - making the cancer insensitive to chemotherapy drugs even after repeated use.

29 Sep 2011

Researchers identify 'programmed cell death' pathway in parasitic worms

Researchers from the Walter and Eliza Hall Institute have for the first time identified a 'programmed cell death' pathway in parasitic worms that could one day lead to new treatments for one of the world's most serious and prevalent diseases.

29 Sep 2011

Acetyl-L-carnitine likely to improve outcomes and recovery for individuals with SCI

A commonly used supplement is likely to improve outcomes and recovery for individuals who sustain a spinal cord injury (SCI), according to research conducted by University of Kentucky neuroscientists.

29 Sep 2011

Some stroke patients may benefit from treatment outside the typical 3 hour window

Stroke victims may have a longer window of opportunity to receive treatment to save their brain cells, demonstrates a literature review published by University of Alberta medical researchers in Lancet Neurology.

28 Sep 2011

Scientists identify proteasome phosphatase that appears to regulate removal of damaged proteins

A study by scientists at the University of California, San Diego and UC Irvine has identified an enzyme called a proteasome phosphatase that appears to regulate removal of damaged proteins from a cell. The understanding of how this process works could have important implications for numerous diseases, including cancer and Parkinson's disease.

28 Sep 2011

Scientists identify a way that chemotherapy causes platelet numbers to drop

Scientists at the Walter and Eliza Hall Institute have identified a way that chemotherapy causes platelet numbers to drop, answering in the process a decade-old question about the formation of platelets, tiny cells that allow blood to clot.

26 Sep 2011

BPA may not affect male testes

Bisphenol A (BPA), a common component of plastic used in many consumer products, has recently become infamous -- and banned in some places -- because it can mimic natural estrogen in the body. A new study by Brown University toxicologists, however, finds that male mice whose mothers were exposed even to high doses of BPA while pregnant developed no signs of harm to their testes as adults.

23 Sep 2011

Adeno-associated virus type 2 kills human breast cancer cells in lab

A nondisease-causing virus kills human breast cancer cells in the laboratory, creating opportunities for potential new cancer therapies, according to Penn State College of Medicine researchers who tested the virus on three different breast cancer types that represent the multiple stages of breast cancer development.

23 Sep 2011

Wnt signaling pathway plays an important role in early-onset dementia

No cure exists for frontotemporal dementia, which strikes between the ages of 40 and 64 and accounts for at least one in four cases of early-onset dementia. Caused by the death of cells in the front and sides of the brain, the disease can lead to dramatic changes in a patient's personality and behavior, including the loss of the ability to communicate.

22 Sep 2011