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Fetal neurons play role in adult brain

Subplate neurons - once thought to die after directing the wiring of the cerebral cortex or gray matter - remain in the white matter of the adult brain in small numbers and maintain activity, communicating with other neurons in the brain said researchers from Baylor College of Medicine and the University of Alabama at Birmingham in a report that appears in today's issue of the Journal of Neuroscience

12 Sep 2007

Customized virus kills brain tumor stem cells that drive lethal cancer

A tailored virus destroys brain tumor stem cells that resist other therapies and cause lethal re-growth of cancer after surgery, a research team led by scientists at the University of Texas M. D. Anderson Cancer Center reports in the Sept. 18 edition of the Journal of the National Cancer Institute.

12 Sep 2007

Diesel exhaust kills throat cells

Researchers at Deakin University have found that diesel exhaust is far more damaging to our health than exhaust from biodiesel, the plant-based fuel.

12 Sep 2007

Mutations in the insulin gene can cause permanent neonatal diabetes

Mutations in the insulin gene can cause permanent neonatal diabetes, an unusual form of diabetes that affects very young children and results in lifelong dependence on insulin injections, report researchers from the University of Chicago and Peninsula University (Exeter, UK) in Sept. 18, 2007, issue of the Proceedings of the National Academy of Sciences, published early online.

11 Sep 2007

A molecular probe that may one day light up tumors while surgery is in progress

Researchers at the Stanford University School of Medicine have developed a molecular probe that sets aglow tumor cells within living animals. Their goal is to use the probe to improve the diagnosis and treatment of cancer and other diseases.

10 Sep 2007

Decitabine and interferon gamma show promise for ocular melanoma that has spread

A combination of two drugs shows promise in treating a rare and therapy-resistant type of melanoma that originates in the eye and spreads to other organs, according to a new study led by Duke University Comprehensive Cancer Center researchers.

5 Sep 2007

Avocado extract stops growth of pre-cancerous cells that lead to oral cancer

Nutrients taken from avocados are able to thwart oral cancer cells, killing some and preventing pre-cancerous cells from developing into actual cancers, according to researchers at Ohio State University.

5 Sep 2007

Muscadine grape skin extract shows promise for prostate cancer

Laboratory experiments show that an extract of the skin of muscadine grapes can inhibit growth of prostate cancer cells in the laboratory.

4 Sep 2007

Study identifies osteopontin as a key player in the body's immune response to chronic stress

Osteopontin (OPN), a protein molecule involved in many different cellular processes, plays a significant role in immune deficiency and organ atrophy following chronic physiological stress, resulting in increased susceptibility to illness.

4 Sep 2007

Mice stressed in simulated weightlessness show organ atrophy

A ground-based, experimental model used to simulate astronaut weightlessness in space has provided Rutgers scientists an opportunity to study the effects of stress on immune organs.

4 Sep 2007

Retinoblastoma tumor suppressor may predict chemotherapy effectiveness

A common molecular pathway could help physicians predict which lung cancer patients will benefit from chemotherapy drugs, according to new research from a multidisciplinary team at the University of Cincinnati (UC).

3 Sep 2007

Inhaling nitric oxide helps transplant success

Administering inhaled nitric oxide (NO) during surgery helps protect liver transplant patients from organ failure, according to a new study from researchers at the University of Alabama at Birmingham (UAB).

30 Aug 2007

Prevalence of algatoxin in the marine environment appears to be increasing

If ingested, for example in seafood, these toxins can lead to discomfort or even illness. The algatoxin yessotoxin (YTX), which is found in both mussels and scallops in Norway, may be a potential disease risk factor in the consumption of seafood. "We don't know the long-term effects of YTX on people", says Monica Suarez Korsnes of the Norwegian School of Veterinary Science (NVH).

30 Aug 2007

Autophagy-induced signals are essential for normal development

A cannibalistic process called autophagy spurs dying embryonic stem cells to send "eat me" and "come get me" signals to have their corpses purged, a last gasp that paves the way for normal mammalian development, UT Southwestern Medical Center researchers have found.

30 Aug 2007

New understanding of endoplasmic reticulum

In obese individuals, fat cells are bloated and inflamed because they receive too many nutrients, including lipids.

29 Aug 2007

FDA grants orphan drug designation to TREANDA

Cephalon, Inc. announced today that the U.S. Food and Drug Administration (FDA) Office of Orphan Products Development granted orphan drug designation for the company's investigational therapy, TREANDA (bendamustine HCl), for the treatment of chronic lymphocytic leukemia (CLL).

29 Aug 2007