Cell Death News and Research

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Scientits devise dimmer swith to regulate gene expression in mammal cells

Three Boston University biomedical engineers have created a genetic dimmer switch that can be used to turn on, shut off, or partially activate a gene's function. Professor James Collins, Professor Charles Cantor and doctoral candidate Tara Deans invented the switch, which can be tuned to produce large or small quantities of protein, or none at all.

27 Jul 2007

The future of Alzheimer's disease research

Imagine the day when a routine visit to the family doctor includes a simple blood test to predict the risk for developing Alzheimer's disease (AD).

26 Jul 2007

Tetrabenazine protects brain cells in Huntington's disease model

A drug used in some countries to treat the symptoms of Huntington's disease prevents death of brain cells in mice genetically engineered to mimic the hereditary condition, UT Southwestern Medical Center researchers have found.

25 Jul 2007

Nanoscale dots target and track apoptosis

Apoptosis, or programmed cell death, is a hallmark effect triggered by effective anticancer drugs. Now, researchers in Korea have developed a biocompatible, fluorescent nanoparticle that could provide an early sign that apoptosis is occurring as a result of anticancer therapy.

23 Jul 2007

Research to look at reasons for the formation of Lewy bodies

A University of Nottingham researcher has been awarded more than £440,000 by the Parkinson’s Disease Society (PDS) to investigate the causes of the condition.

23 Jul 2007

Scientists clarify molecular basis of interferon action

Scientists at the University of California, Santa Barbara have made a significant discovery relating to viral infections in humans.

20 Jul 2007

Suicide gene therapy for cancer

Cutting-edge research at South Dakota State University may yield a new therapy that targets only cancer cells, leaving healthy cells unharmed.

18 Jul 2007

Researchers identify new combination therapy that promotes cancer cell death

Researchers at the University of Pennsylvania School of Medicine identified a combination therapy as a way to sensitize resistant human cancer cells to a treatment currently being tested in clinical trials They propose that the therapy may help to selectively eliminate cancer cells while leaving healthy cells intact, providing a cancer treatment with fewer side effects.

17 Jul 2007

Bak protein's deadly double whammy

When a cell is seriously stressed, say by a heart attack, stroke or cancer, a protein called Bak just may set it up for suicide, researchers have found.

13 Jul 2007

New advance in search for effective treatment for human liver cancer

Researchers from the University of Pittsburgh School of Medicine report a significant new advance in the search for an effective treatment for human liver cancer in the July issue of Molecular Cancer Therapeutics.

12 Jul 2007

Genetically engineered herpes simplex virus keeps arteries free-flowing

A genetically engineered herpes simplex virus, primarily known for causing cold sores, may help keep arteries "free-flowing" in the weeks following angioplasty or stent placement for patients, according to research published early in the online edition of PNAS (Proceedings of the National Academy of Sciences of the United States of America).

11 Jul 2007

Magnetic nano tweezers show how cancer drug works

The annoying bulges of an over-wound telephone cord that shorten its reach and limit a caller's motion help to explain why drugs called camptothecins are so effective in killing cancer cells, according to investigators at St. Jude Children's Research Hospital and Delft University of Technology.

10 Jul 2007

Scientists take exciting approach for attacking cancers

A new study identifies a combination therapy that may sensitize human cancer cells to a promising treatment currently being used in clinical trials.

10 Jul 2007

Rapid evolution of defense genes in plants may produce hybrid incompatibility

One of the basic tenets of evolution is speciation in which populations of the same species become so genetically and morphologically variable that they can be classified as two different species.

10 Jul 2007

Orlistat weight loss drug points to new cancer treatments

Based on their surprising discovery that an obesity drug can kill cancer cells, scientists at Wake Forest University School of Medicine have made a new finding about the drug's effects and are working to design more potent cancer treatments.

9 Jul 2007

Gene found that protects from serious kidney disease

A combination of mice and patient studies sheds light on cause and possible new therapies of kidney diseases.

8 Jul 2007

New working principle in cancer treatment

Due to defects in chromosomal distribution, a majority of tumor cells would not be able to survive were it not for a trick that cancer cells have developed to avoid this chaos in the genetic material.

5 Jul 2007

Myeloperoxidase offers clues to heart attack in seemingly healthy people

We've all wondered how a seemingly healthy person can actually be at high risk for heart disease or a heart attack.

4 Jul 2007

Myeloperoxidase protein provides clues to heart attacks in healthy people

We've all wondered how a seemingly healthy person can actually be at high risk for heart disease or a heart attack.

4 Jul 2007

Substance from lapacho tree could lead to new lung-cancer treatment

Researchers at UT Southwestern Medical Center have determined how a substance derived from the bark of the South American lapacho tree kills certain kinds of cancer cells, findings that also suggest a novel treatment for the most common type of lung cancer.

26 Jun 2007