Cell Line News and Research

RSS

Gut bacteria and tryptophan diet can play a protective role against pathogenic E. coli

Gut bacteria and a diet rich in the amino acid tryptophan can play a protective role against pathogenic E. coli, which can cause severe stomach upset, cramps, fever, intestinal bleeding and renal failure, according to a study published March 13 in Nature.

14 Mar 2024

Breakthrough gene silencing method slashes cholesterol for a year in mice, no DNA damage

Researchers developed an engineered transcriptional repressor that durably silences the Pcsk9 gene in mice, reducing cholesterol levels for up to a year with a single treatment, showcasing a potential breakthrough in genetic disorder treatments without the risks of DNA mutation.

29 Feb 2024

BioCina and NovaCina forge strategic alliance to offer biologics developers integrated drug substance and drug product solutions

BioCina Pty Ltd., a global end-to-end biologics Contract Development and Manufacturing Organisation (CDMO), and NovaCina Pty Ltd., a global fill-and-finish CDMO, announced a strategic partnership to provide integrated drug substance and drug product solutions for biologics developers.

From BioCina Pty Ltd. 29 Feb 2024

Universal, essential biomarker identified for childhood neuroblastoma

Researchers have newly identified a universal, essential biomarker for the childhood cancer neuroblastoma – and a potential new target for treatment.

27 Feb 2024

Discovery of bicarbonate-sensing receptor offers therapeutic insights into ischemic stroke treatment

Researchers have identified this receptor in brain mural cells that regulates reperfusion injury.

27 Feb 2024

Bio-Rad launches vericheck ddPCR replication competent lentivirus and replication competent AAV kits for cell and gene therapy production

Rapid, Sensitive, and Validated Detection of Viral Replication Genes Using Droplet Digital™ PCR During Cell and Gene Therapy Production.

From Bio-Rad Laboratories 27 Feb 2024

Study reveals how long COVID can affect brain function through vascular disruption

The neurological response to coronavirus disease 2019 (COVID-19) may be due to brain-brain barrier (BBB) disruption.

26 Feb 2024

Novel splicing mechanism for short introns discovered

Researchers confirm that the established pre-mRNA splicing mechanism that appears in textbooks cannot work in a subset of human short introns: A novel SAP30BP–RBM17 complex-dependent splicing has been uncovered.

15 Feb 2024

Drug repurposing study finds lonafarnib effective against RSV

A study in Nature Communications identifies lonafarnib from the ReFRAME drug-repurposing library as a potent inhibitor of the RSV fusion protein, showing promise in reducing RSV infection in vitro and in vivo.

11 Feb 2024

Resveratrol can combat Alzheimer's via inflammatory suppression, study shows

Study demonstrates Resveratrol's ability to mitigate Alzheimer's Disease (AD) symptoms by inhibiting proinflammatory responses and promoting antioxidant enzyme expression in microglial cell lines, offering insights into its neuroprotective mechanisms.

5 Feb 2024

MSU scientists unveil a potential game-changer in the fight against glioblastoma

A team of Michigan State University scientists has unveiled a potential game-changer in the fight against glioblastoma, the most common and currently incurable form of brain cancer.

5 Feb 2024

Revvity showcases cutting-edge solutions at SLAS2024

Revvity presents its continued commitment to expanding the boundaries of human potential through science.

From Revvity 5 Feb 2024

X-chromosome inactivation and its role in autoimmune susceptibility in females

Somewhere between 24 and 50 million Americans have an autoimmune disease, a condition in which the immune system attacks our own tissues. As many as 4 out of 5 of those people are women.

1 Feb 2024

Immune protein Ku70 key in fighting bowel cancer

Study establishes Ku70's role in tumor suppression, showing that reduced expression or mutations in this DNA repair protein significantly increase intestinal cancer risk.

30 Jan 2024

Asimov launches LV Edge Packaging System to optimize lentivirus production

New off-the-shelf system reduces the cost and risk of lentiviral (LV) production for cell and gene therapy developers.

From Asimov 29 Jan 2024

New workflow identifies shared cancer targets, advancing immunotherapy

Researchers developed the Splicing Neo Antigen Finder (SNAF) workflow, integrating deep learning to identify shared immunogenic neoantigens in cancers, offering new targets for cancer immunotherapy, particularly in melanoma and ovarian cancer.

23 Jan 2024

Scientists develop noninvasive way to monitor gene expression dynamics in the brain

Researchers introduced a non-invasive, sensitive method for monitoring gene expression in the brain using engineered reporters called released markers of activity, which can exit the brain into the blood for easy detection.

12 Jan 2024

Association between vitamin D supplementation and fatigue

The mechanisms underlying vitamin D’s effects on fatigue.

12 Jan 2024

New Omicron subvariants test vaccine limits, reveal unique infection challenges

Study reveals that the Omicron subvariants BA.2.86 and FLip show unique mutations and infectivity profiles, with BA.2.86 being highly infectious and resistant to most conventional antibodies, underscoring the need for updated vaccines.

9 Jan 2024

Itchy skin? Possible atopic dermatitis? Lavender essential oil might be just what you're looking for

Researchers demonstrate that lavender essential oils, particularly linalyl acetate, effectively suppress atopic dermatitis without skin sensitization, offering a natural, accessible treatment option.

8 Jan 2024