Cell Membrane News and Research

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New discovery may lead to targeted therapy for migraines

A PhD student at Xi'an Jiaotong-Liverpool University in Suzhou, China is carrying out work that could have a significant impact on drugs developed to prevent and treat migraines.

16 Nov 2016

TSRI study unravels how protein is directly responsible for sensing touch

A new study led by scientists at The Scripps Research Institute reveals that a protein first discovered at TSRI in 2010 is directly responsible for sensing touch.

14 Nov 2016

Researchers identify mechanism of how circadian clocks in neurons encode daily rhythms of excitability

Molecular clocks in cells throughout the body control many physiologic changes in a 24-hour day/night circadian rhythm -- among them the timing of sleep and wakefulness.

14 Nov 2016

Elucidating IDP behaviour on crowded membranes

IDPs are proteins that contain stretches of amino-acid sequence that are flexible and do not comprise stable structure in isolation. This is in contrast with a more traditional view of proteins as largely occupying a stable native structure that correlates with functions such as enzyme activity or binding.

10 Nov 2016

NCATS funds collaboration initiative aimed at repurposing antimalarial to combat Ebola virus

The National Center for Advancing Translational Sciences recently awarded $596,533.00 to Collaborations Pharmaceuticals, Inc. to initiate a partnership with Texas Biomedical Research Institute aimed at repurposing an antimalarial for use against the Ebola virus.

10 Nov 2016

New treatment with therapeutic short interfering RNA could help thwart cancer

In the fight against cancer, doctors dish out combination-blows of surgery, chemotherapy and other drugs to beat back a merciless foe. Now, scientists have taken early steps toward adding a stinging punch to clinicians' repertoire.

7 Nov 2016

Researchers identify heart defects in progeria patients that may raise risk of arrhythmias, premature death

Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III, working in collaboration with colleagues at other centers in Spain and abroad, have identified defects in the hearts of progeria patients that appear to be related to an elevated risk of arrhythmias and premature death.

2 Nov 2016

Problems with nuclear membrane play role in leukemia, heart disease and aging disorders

We put things into a container to keep them organized and safe. In cells, the nucleus has a similar role: keeping DNA protected and intact within an enveloping membrane.

2 Nov 2016

Researchers identify possible trigger of chronic inflammation in people with diabetes

Inflammation is one of the main reasons why people with diabetes experience heart attacks, strokes, kidney problems and other, related complications. Now, in a surprise finding, researchers at Washington University School of Medicine in St. Louis have identified a possible trigger of chronic inflammation.

2 Nov 2016

Study reveals potential therapeutic targets for treating patients who carry IFNGR receptor mutation

The study began by taking the medical history of 11 children, all of whom had a disorder due to mycobacteria infections, as the basis. All were discovered to have the same phenotype with the same mutation, which was located in the interferon-gamma (IFNGR) receptor, so the group began to explore what was causing this dysfunction.

27 Oct 2016

New study raises serious safety concerns in clinical use of caspase inhibitors for liver injury

Many acute and chronic liver diseases, including alcoholic hepatitis, result from apoptotic (programmed) cell death mediated by the enzyme caspase.

20 Oct 2016

Novel device that uses gold nanowires may benefit biomedical professionals during medical procedures

Grown like a snowflake and sharpened with a sewing machine, a novel device by Kansas State University researchers may benefit biomedical professionals and the patients they serve during electrode and organ transplant procedures.

20 Oct 2016

DZNE scientists find new mechanism that allows damaged neurons to regenerate

Injuries to the spinal cord can cause paralysis and other permanent disabilities because severed nerve fibers do not regrow. Now, scientists of the German Center for Neurodegenerative Diseases have succeeded in releasing a molecular brake that prevents the regeneration of nerve connections.

7 Oct 2016

GDE2 protein could help predict course of neuroblastoma

The research group of Wouter Moolenaar of the Netherlands Cancer Institute (NKI) has, in collaboration with the group of Rogier Versteeg of the AMC Amsterdam, discovered a protein that can predict the course of neuroblastoma.

4 Oct 2016

Researchers uncover pneumonia causing bacteria as trigger for autoimmune disease GBS

Guillain-Barré syndrome (GBS) is an acute life-threatening disease of the nervous system that leads to sensory disturbances and acute flaccid paralysis.

3 Oct 2016

X-ray laser-based technology enables faster structural analysis of receptor proteins

An international team of scientists has learnt how to determine the spatial structure of a protein obtained with an X-ray laser using the sulfur atoms it contains. This development is the next stage in the project of a group led by Vadim Cherezov to create an effective method of studying receptor proteins.

30 Sep 2016

Cell Membrane News and Research

New discovery may lead to targeted therapy for migraines

TSRI study unravels how protein is directly responsible for sensing touch

Researchers identify mechanism of how circadian clocks in neurons encode daily rhythms of excitability

Elucidating IDP behaviour on crowded membranes

NCATS funds collaboration initiative aimed at repurposing antimalarial to combat Ebola virus

New treatment with therapeutic short interfering RNA could help thwart cancer

Researchers identify heart defects in progeria patients that may raise risk of arrhythmias, premature death

Problems with nuclear membrane play role in leukemia, heart disease and aging disorders

Researchers identify possible trigger of chronic inflammation in people with diabetes

Study reveals potential therapeutic targets for treating patients who carry IFNGR receptor mutation

New study raises serious safety concerns in clinical use of caspase inhibitors for liver injury

Novel device that uses gold nanowires may benefit biomedical professionals during medical procedures

DZNE scientists find new mechanism that allows damaged neurons to regenerate

GDE2 protein could help predict course of neuroblastoma

Researchers uncover pneumonia causing bacteria as trigger for autoimmune disease GBS

X-ray laser-based technology enables faster structural analysis of receptor proteins

Researchers discover how signals from infectious bacteria get to inflammasome sensors

CUMC researchers uncover new details of intracellular channel that controls skeletal muscle

KIT researchers use high-resolution microscopy to uncover how scavenger cells repair muscle fibers

Researchers propose new explanation for symptoms of fragile X syndrome

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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