Cell Metabolism News and Research

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Study reveals limited effects of longevity treatments on the aging process

Three approaches with a reputation for slowing aging processes have proven largely ineffective. For their study, researchers developed a new method to measure aging, which accounts for the complexity of aging in organisms.

14 Dec 2022

Protein kinase CK2 controls CD8+ T cell effector and memory functions during Listeria infection

The protein kinase CK2 is involved in a wide range of biological processes and cellular functions, including inflammatory responses and pathologies associated with inflammation.

1 Nov 2022

Faulty gene may explain why some people gain excessive weight despite normal food intake

A faulty gene, rather than a faulty diet, may explain why some people gain excessive weight even when they don't eat more than others, UT Southwestern researchers at the Center for the Genetics of Host Defense have discovered.

28 Oct 2022

Study provides new insights into genetic form of frontotemporal dementia

Dementia encompasses a range of neurodegenerative conditions that lead to memory loss and cognitive deficiencies and affect some 55 million people worldwide.

28 Oct 2022

Immune checkpoint therapy may be beneficial in certain cases of severe COVID-19

An article published in Science Advances suggests that a type of cancer treatment known as immune checkpoint blockade may be beneficial in certain cases of severe COVID-19.

27 Oct 2022

Rheumatoid arthritis drug can be repurposed to improve diabetes-associated symptoms

Researchers at Baylor College of Medicine and collaborating institutions discovered that the rheumatoid arthritis drug auranofin can potentially be repurposed to improve diabetes-associated symptoms.

14 Oct 2022

Mic60-low gene signature may be a simple tool to estimate pancreatic cancer risk

The mitochondria is a key energy-producing component of the human cell that plays an important role in cancer cell metabolism.

12 Oct 2022

Researchers discover how cancer cells can turn off the immune system to help tumors grow

When cancer arises in the body, it starts with tumor cells that rapidly grow and divide and eventually spread.

29 Sep 2022

The impact of the infant gut microbiome on vaccine efficacy

A new study reports the effect of the infant gut microbiome on vaccine efficacy.

13 Sep 2022

Is there a right time for eating?

In a recent study published in the journal Cell Metabolism, researchers assessed how calorie or energy intake (EI) time influences calorie distribution and all energy expenditure (EE) components, which, in turn, impact energy balance and weight loss in healthy obese people.

12 Sep 2022

Morning-loaded and evening-loaded diets produce similar weight loss, with no energy metabolism differences

There's the old saying in dieting that one must "breakfast like a king, lunch like a prince, and dine like a pauper," based on the belief that consuming the bulk of daily calories in the morning optimizes weight loss by burning calories more efficiently and quickly.

12 Sep 2022

Tumor-derived factors stimulate effector trogocytosis and inhibit CAR T cells

The immune system is equipped to respond not just to external invaders-;think viruses, bacteria, and parasites-;but also to internal threats, namely, cancer. Yet, frequently, malignancies overcome the immune system's defenses and evade detection.

12 Sep 2022

Researchers use 3D mapping techniques to identify multiple genes implicated in type 2 diabetes

Researchers from Children's Hospital of Philadelphia used advanced three-dimensional mapping techniques at a microscopic level to identify a multitude of genetic variants and corresponding target gene pairings in the pancreas that are implicated in type 2 diabetes.

6 Sep 2022

Immune cells preferentially use cellular waste products to power their function

The immune cells that protect us from infection and cancer seek out a wide array of fuel sources to power their function -; including some long thought to be cellular waste products.

17 Aug 2022

Study pinpoints a three-pronged approach that makes liver cancer cells stop growing

Liver cancer's rapid growth leads to a vulnerability in its energy-production and cell-building processes that may be potently exploited with a new combination-treatment strategy, according to a study from researchers at the Perelman School of Medicine at the University of Pennsylvania.

3 Aug 2022

Study reveals a specific metabolic adaptation in some patients with acute myeloid leukemia

An article published in the journal Nature Communications describes a specific metabolic adaptation in some patients with acute myeloid leukemia affected by tandem mutations in the FLT3 gene.

13 Jul 2022

The smell and sight of a meal stimulate short-lived inflammatory response in the brain

Even before carbohydrates reach the bloodstream, the very sight and smell of a meal trigger the release of insulin.

30 Jun 2022

Drug combinations may help to slow the progression of diabetic kidney disease

A mouse study led by Washington University School of Medicine in St. Louis suggests that combining SGLT2 inhibitors — a newer class of diabetes medications that lowers blood sugar — with older diabetes drugs may help to slow the progression of diabetic kidney disease.

15 Jun 2022

Scientists find new link between high-fat, high-fructose diets and Type 2 diabetes mellitus

Those who are habitually inclined to consume burgers, fries and soda may think twice about their dietary choices following scientists' latest findings about high-fat, high-fructose diets.

10 Jun 2022

Proteomic analysis of 2002 tumors reveals 11 distinct pan-cancer molecular subtypes

A new study that analyzed protein levels in 2,002 primary tumors from 14 tissue-based cancer types identified 11 distinct molecular subtypes, providing systematic knowledge that greatly expands a searchable online database that has become a go-to platform for cancer data analysis by users worldwide.

10 Jun 2022

Cell Metabolism News and Research

Study reveals limited effects of longevity treatments on the aging process

Protein kinase CK2 controls CD8+ T cell effector and memory functions during Listeria infection

Faulty gene may explain why some people gain excessive weight despite normal food intake

Study provides new insights into genetic form of frontotemporal dementia

Immune checkpoint therapy may be beneficial in certain cases of severe COVID-19

Rheumatoid arthritis drug can be repurposed to improve diabetes-associated symptoms

Mic60-low gene signature may be a simple tool to estimate pancreatic cancer risk

Researchers discover how cancer cells can turn off the immune system to help tumors grow

The impact of the infant gut microbiome on vaccine efficacy

Is there a right time for eating?

Morning-loaded and evening-loaded diets produce similar weight loss, with no energy metabolism differences

Tumor-derived factors stimulate effector trogocytosis and inhibit CAR T cells

Researchers use 3D mapping techniques to identify multiple genes implicated in type 2 diabetes

Immune cells preferentially use cellular waste products to power their function

Study pinpoints a three-pronged approach that makes liver cancer cells stop growing

Study reveals a specific metabolic adaptation in some patients with acute myeloid leukemia

The smell and sight of a meal stimulate short-lived inflammatory response in the brain

Drug combinations may help to slow the progression of diabetic kidney disease

Scientists find new link between high-fat, high-fructose diets and Type 2 diabetes mellitus

Proteomic analysis of 2002 tumors reveals 11 distinct pan-cancer molecular subtypes

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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