Cell Nucleus News and Research

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A simple spit test could predict cancers

In future scientists say, a test as simple as spitting into a collection tube or cup might be a screening test for breast cancer and the early detection of other tumours.

19 Apr 2005

Drugs targeted at muscle cells can be of use in the treatment of diabetes patients with insulin resistance

Type 2 diabetes is a clinical disease characterised by disruption to the metabolism of glucose and lipids as well as to the production of and physiological reactions to insulin.

19 Apr 2005

Molecular motors cooperate in moving cellular cargo

Researchers using an extremely fast and accurate imaging technique have shed light on the tiny movements of molecular motors that shuttle material within living cells. The motors cooperate in a delicate choreography of steps, rather than engaging in the brute-force tug of war many scientists had imagined.

7 Apr 2005

Research helps understand how the malaria parasite disguises itself to avoid detection by the immune system

Scientists are making strides in understanding how the malaria parasite Plasmodium falciparum disguises itself to avoid detection by the immune system. The findings could lead to the development of new drugs for a disease that causes more than 300 million acute illnesses and at least one million deaths each year, most of them in developing countries.

7 Apr 2005

Process called sumoylation regulates key ion channel

Researchers at the University of Chicago have found that a recently discovered biological process known as sumoylation -- until now thought to be active only in the nucleus -- also occurs near the cell's surface where it regulates at least one and possibly many kinds of proteins, providing a novel target for the development of new drugs.

7 Apr 2005

Yeast discovery provides new insights into familial dysautonomia

A discovery in yeast that has important implications for finding a cure for a devastating disease of nerve cell failures -- called familial dysautonomia (FD) -- has been made by Cornell University researchers.

6 Apr 2005

DNA packaging linked with cancer

New laboratory findings at the University of Illinois at Chicago suggest that what lies outside cancer cells is at least as important as the genes inside in explaining a tumor's malignancy.

5 Apr 2005

DNA sequencing made portable and faster by "colour-blind" technology

Researchers at Baylor College of Medicine (BCM) and Rice University have developed a"colour-blind" method of fluorescence detection which could open new doors that would take DNA sequencing to the patient's bedside, the doctor's office and even the scene of a crime or a battlefield.

29 Mar 2005

Discovery of gene STAT6(B) may lead to new treatments for inflammatory diseases

In a paper featured in Proceedings of the National Academy of Science (PNAS), researchers from Boston University School of Dental Medicine report the discovery of a new gene, STAT6(B), that helps regulate production of the potentially deadly tumor necrosis factor alpha (TNF-alpha) cytokine.

28 Mar 2005

KCP protein protects kidneys from damage caused by chronic renal disease and injury

University of Michigan scientists have identified a new and unusual protein that reduces, in laboratory mice, kidney damage caused by chronic renal disease and acute toxic injuries.

28 Mar 2005

Ultrafast laser detection of cancer cells also may improve understanding of stem cells

To investigate tumors, pathologists currently rely on labor-intensive microscopic examination, using century-old cell-staining methods that can take days to complete and may give false readings.

23 Mar 2005

Study suggests combination therapy could stop spread, halt growth of melanomas

Researchers at Penn State College of Medicine have identified the mechanism by which the most mutated gene in melanoma, called v599EB-Raf, aids melanoma tumor development demonstrating its importance as a therapeutic target.

22 Mar 2005

Smart nanocarrier technology will cancer treatment

A ‘smart’ nanocarrier technology developed by a team of researchers at the Institute of Bioengineering and Nanotechnology (IBN) is set to vastly improve the way cancer patients are treated.

22 Mar 2005

Findings are expected to yield new diagnostic and therapeutic tools in the battle against cancer

New laboratory findings at the University of Illinois at Chicago suggest that what lies outside cancer cells is at least as important as the genes inside in explaining a tumor's malignancy.

22 Mar 2005

New research in mice sheds light on the causes behind male infertility

For 40 percent of the estimated six million American couples battling infertility, the problem lies with the man. But help may be on the way.

21 Mar 2005

Most comprehensive genome-wide experimental analyses of sense-antisense transcripts to date

A team of scientists led by Dr. Kuniya Abe from the RIKEN BioResource Center in Japan has performed one of the most comprehensive genome-wide experimental analyses of sense-antisense transcripts to date. Their findings are published in the April issue of the journal Genome Research.

15 Mar 2005

RNA interference as promising therapy for ALS

Scientists at the Ecole Polytechnique Fédérale de Lausanne (EPFL) in Switzerland have used RNA interference in transgenic mice to silence a mutated gene that causes inherited cases of amytrophic lateral sclerosis (ALS), substantially delaying both the onset and the progression rate of the fatal motor neuron disease.

13 Mar 2005

Vasoactive intestinal polypeptide needed by the brain's biological clock to coordinate daily rhythms

A biologist at Washington University in St. Louis is giving the VIP treatment to laboratory mice in hopes of unraveling more clues about our biological clock.

7 Mar 2005

New therapeutic targets in liver diseases

Many patients with liver diseases often encounter difficulties with therapy and ultimately require liver transplant to survive. Since many acute and chronic liver diseases are driven by immune-mediated mechanisms, there is a necessity to find new therapies that can inhibit these immune-based triggers and block liver damage.

6 Mar 2005

Discovery gives clinicians new targets for making existing therapies more effective and developing drugs to inhibit the growth of cancers

A team of researchers at the University of Alberta in Edmonton and the Samuel Lunenfeld Research Institute in Toronto have discovered how a key enzyme involved in repairing DNA is put together and how it works--a development that opens up new therapies for making cancer cells more vulnerable to attack.

3 Mar 2005

Cell Nucleus News and Research

A simple spit test could predict cancers

Drugs targeted at muscle cells can be of use in the treatment of diabetes patients with insulin resistance

Molecular motors cooperate in moving cellular cargo

Research helps understand how the malaria parasite disguises itself to avoid detection by the immune system

Process called sumoylation regulates key ion channel

Yeast discovery provides new insights into familial dysautonomia

DNA packaging linked with cancer

DNA sequencing made portable and faster by "colour-blind" technology

Discovery of gene STAT6(B) may lead to new treatments for inflammatory diseases

KCP protein protects kidneys from damage caused by chronic renal disease and injury

Ultrafast laser detection of cancer cells also may improve understanding of stem cells

Study suggests combination therapy could stop spread, halt growth of melanomas

Smart nanocarrier technology will cancer treatment

Findings are expected to yield new diagnostic and therapeutic tools in the battle against cancer

New research in mice sheds light on the causes behind male infertility

Most comprehensive genome-wide experimental analyses of sense-antisense transcripts to date

RNA interference as promising therapy for ALS

Vasoactive intestinal polypeptide needed by the brain's biological clock to coordinate daily rhythms

New therapeutic targets in liver diseases

Discovery gives clinicians new targets for making existing therapies more effective and developing drugs to inhibit the growth of cancers

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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