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Gene amplification links growth controlling pathway from Drosophila to human cancers

Researchers at Harvard Medical School (HMS) and Massachusetts General Hospital (MGH) have discovered a new cancer-promoting role for a gene potentially involved in breast, liver, and other kinds of cancers.

8 Aug 2006

Federally approved human embryonic stems inferior to those donated for research

Neural stem cells grown from one of the federally approved human embryonic stem cell lines proved to be inferior to neural stem cells derived from fetal tissue donated for research, a UCLA study has found.

4 Aug 2006

Researchers test possibility of growing kidneys for transplant

Bioengineers from the Medical University of South Carolina and Clemson University believe their research has the potential to save the lives of thousands of patients desperately waiting for a kidney while, at the same time, cutting costs associated with kidney disease.

2 Aug 2006

Molecular switch that regulates fat and cholesterol production identified

Researchers at Harvard Medical School and Massachusetts General Hospital have identified how a molecular switch regulates fat and cholesterol production

2 Aug 2006

How kidneys retain proteins, discard waste

New research may finally settle a decades-old debate about how the kidney keeps valuable blood proteins from harmfully slipping into the urine, a serious health symptom that often precedes kidney failure.

2 Aug 2006

Researchers determine why gene therapy treatment caused leukemia in some X-linked severe combined immunodeficiency patients

Scientists at St. Jude Children's Research Hospital have developed a mouse model of a severe disease of the immune system that helps explain why gene therapy used to treat children with this disease at an institution in Europe caused some of them to develop leukemia.

2 Aug 2006

Genetic key to treating deadly fungal infections

University of Minnesota researchers have discovered how a prevalent fungal pathogen that causes 10,000 deaths per year in the United States overcomes the effects of antifungal drugs by duplicating a section of one of its chromosomes.

24 Jul 2006

Evotec sells single molecule detection technology to Olympus

Evotec AG has announced that its Tools and Technologies Division has sold the core of its Single Molecule Detection Technology and transferred or licensed the corresponding IP portfolio to Olympus Corporation, Tokyo, Japan.

From Evident Corporation - Life Sciences 24 Jul 2006

Leukemia gene normally has mammary gland function

A gene critical for normal mammary gland function during nursing helps trigger highly lethal leukemias when it undergoes a mutation that fuses it to another gene, according to investigators at St. Jude Children's Research Hospital.

19 Jul 2006

Secrets of cells revealed

With the advancement of technology we are managing to see ever smaller and smaller pieces of the puzzle that is life.

17 Jul 2006

World-first stem cell research may help male infertility

Scientists have shown for the first time that sperm grown from embryonic stem cells can be used to produce offspring.

10 Jul 2006

Study shows eggs survive in older ovaries

In research that could have broad implications for women's fertility treatments, scientists have found that despite their age, female mice have a renewable egg supply in their ovaries.

5 Jul 2006

Female mice found to have a renewable egg supply

In research that could have broad implications for women's fertility treatments, scientists have found that despite their age, female mice have a renewable egg supply in their ovaries.

4 Jul 2006

Researchers develop T-cells from human embryonic stem cells

Human embryonic stem cells can be genetically manipulated and coaxed to develop into mature T-cells, raising hopes for a gene therapy to combat AIDS.

3 Jul 2006

Stem cells contain immortal DNA

EuroStemCell scientists at the Pasteur Institute in Paris have demonstrated one of the body's most sophisticated ways of regulating the genetic material of stem cells.

26 Jun 2006

From DNA to RNA to protein

Of the thousands of proteins produced in our cells, few are as important as the enzyme RNA polymerase (RNAP), which has the unique ability to faithfully copy genetic information from DNA.

18 Jun 2006

Circulating bone-marrow derived cells do not contribute to egg formation

Ovulated egg cells, or oocytes, in adult female mice are not formed from germ cells in the blood or bone marrow.

14 Jun 2006

Evidence of RNA in structures essential to cell division

Evidence for the first time that centrosomes, which play a key role in cell division, may carry their own genetic machinery, answering a controversial question of long standing.

14 Jun 2006

Mechanism for neurodenegerative diseases linked to transport proteins

Hampering the transport of proteins within cells may underlie several adult-onset neurodegenerative diseases, such as Huntington's, ALS and Kennedy disease. Understanding how this cell transport is blocked in these diseases may offer targets for future therapy.

9 Jun 2006

The antimicrobial peptide cathelicidin protects the urinary tract against invasive bacterial infection

Researchers at Karolinska Institutet in Sweden have succeeded in explaining how the body protects itself against urinary tract infections; with the help of an endogenous antibiotic.

9 Jun 2006