Cellular Biology News and Research

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Discovery may lead to new therapies for leukemia

Researchers from the University of Pennsylvania School of Medicine found that a protein called NF-Ya activates several genes known to regulate the development of hematopoietic stem cells (HSC), or blood-producing stem cells, in bone marrow.

2 Aug 2005

Aging profile of the human brain differs greatly from that seen in chimpanzees

Researchers have found that the two primary areas of the human brain appear to age in radically different ways: The cortex used in higher-level thought undergoes more extensive changes with age than the cerebellum, which regulates basic processes such as heartbeat, breathing and balance.

2 Aug 2005

Drugs with similar chemical attributes as Ecstasy might offer useful alternatives to current therapies for Parkinson's disease

Amphetamines, including the drug popularly known as Ecstasy, can reverse the symptoms of Parkinson's disease in mice with an acute form of the condition, according to new research at Duke University Medical Center.

2 Aug 2005

Arf gene prevents excessive growth of blood vessels in the developing eye

A gene better known for its role in preventing cancer also plays a key role in the developing embryo, where the gene prevents excessive growth of blood vessels, according to investigators at St. Jude Children's Research Hospital.

2 Aug 2005

New understanding of cell movement may yield ways to brake cancer's spread

From birth until death, our cells migrate: nerve cells make their vital connections, embryonic cells move to the proper places to form organs, immune cells zero in to destroy pathogenic organisms, and cancer cells metastasize, spreading deadly disease through the body. Scientists studying these migrations didn't know how cells determined where to go. Until now.

1 Aug 2005

Defect in the mechanics of motors that build tiny cellular hairs is the basis of Bardet-Biedl syndrome

A defect in the mechanics of motors that build tiny cellular hairs is the basis of a serious genetic disorder, according to researchers at UC Davis and Simon Fraser University, Canada.

1 Aug 2005

Action of dopamine may be particularly important for understanding psychiatric conditions

Duke University Medical Center researchers have discovered a new mechanism by which chronically high levels of the neurotransmitter dopamine exert their effects on the brain.

28 Jul 2005

Single protein regulates secretion levels - helps stem cells become secretory cells

Johns Hopkins researchers have discovered that a single protein regulates secretion levels in the fruit fly's salivary gland and its skin-like outer layer.

26 Jul 2005

Scientists have identified the first genetic mutations that cause the aorta to widen, tear and rupture

Finding biological markers that flag aneurysm, a bulging of the aorta that leads to dissection, a lengthwise separation of tissues in the artery wall, is critically important for early diagnosis.

25 Jul 2005

New compound ruboxistaurin may decrease vision loss in diabete

A multicenter international study chaired by a Joslin Diabetes Center investigator and reported in the July issue of the American Diabetes Association's journal Diabetes brings hopeful news to the 18 million people in the United States -- and millions more worldwide -- with type 1 or type 2 diabetes.

15 Jul 2005

Our thirst for novelty begins in the eye itself

Researchers at Harvard University have found evidence that the retina actively seeks novel features in the visual environment, dynamically adjusting its processing in order to seek the unusual while ignoring the commonplace. The scientists report in this week's issue of the journal Nature on their finding that this principle of novelty-detection operates in many visual environments.

13 Jul 2005

X-ray crystallography images show how a protein called alpha-actinin performs molecular ballet

As a cell moves forward, physical stress on its skeleton triggers molecular fingers and arms to grasp each other in reinforcing links that stabilize the skeleton, according to images produced by investigators at St. Jude Children's Research Hospital.

12 Jul 2005

Researchers find molecule ephrin-B3 inhibits regrowth of spinal nerve cells

A molecule that helps the body's motor nerve cells grow along proper paths during embryonic development also plays a major role in inhibiting spinal-cord neurons from regenerating after injury, researchers at UT Southwestern Medical Center have found.

11 Jul 2005

New approach to preventing or reversing heart failure

Duke University Medical Center researchers have identified a new protein that plays a critical role in enabling the heart to respond to such external stimuli as exercise or stress, as well as in the progressive loss of heart function that is heart failure, the researchers said.

11 Jul 2005

Study is the first to show that there are mechanisms in place for the immune system to identify cancer cells

A study undertaken by biologists at the University of California, Berkeley, has found that damage to a cell's DNA sets off a chain reaction that leads to the increased expression of a marker recognized by the body's immune system.

6 Jul 2005

Researchers have identified a highly specific pathway that causes inflammation in lung tissue

...a discovery that could help in the design of more targeted treatments for patients with various lung diseases, including cystic fibrosis.

30 Jun 2005

Adult, or post-natal, stem cells have the same ability as embryonic stem cells to multiply

In a ground-breaking study, scientists at Children's Hospital of Pittsburgh have discovered that adult, or post-natal, stem cells have the same ability as embryonic stem cells to multiply, a previously unknown characteristic indicating that post-natal stem cells may play an important therapeutic role.

27 Jun 2005

Researchers successfully treat laboratory model of a lysosomal storage disease called GM1

Physicians might one day be able to treat a disease that destroys brain cells in children using genetically modified cells to transport a "drug" to the site of the dying neural cells (cells that transmit impulses).

27 Jun 2005

Adult, or post-natal, stem cells have the same ability as embryonic stem cells to multiply

27 Jun 2005

New research tool replicates extreme environmental conditions to help understand the human body's response to everyday stresses

A new research tool will allow University of Oregon scientists to replicate an extreme range of environmental conditions in their quest to test and understand the human body's response to everyday stresses.

21 Jun 2005

Cellular Biology News and Research

Discovery may lead to new therapies for leukemia

Aging profile of the human brain differs greatly from that seen in chimpanzees

Drugs with similar chemical attributes as Ecstasy might offer useful alternatives to current therapies for Parkinson's disease

Arf gene prevents excessive growth of blood vessels in the developing eye

New understanding of cell movement may yield ways to brake cancer's spread

Defect in the mechanics of motors that build tiny cellular hairs is the basis of Bardet-Biedl syndrome

Action of dopamine may be particularly important for understanding psychiatric conditions

Single protein regulates secretion levels - helps stem cells become secretory cells

Scientists have identified the first genetic mutations that cause the aorta to widen, tear and rupture

New compound ruboxistaurin may decrease vision loss in diabete

Our thirst for novelty begins in the eye itself

X-ray crystallography images show how a protein called alpha-actinin performs molecular ballet

Researchers find molecule ephrin-B3 inhibits regrowth of spinal nerve cells

New approach to preventing or reversing heart failure

Study is the first to show that there are mechanisms in place for the immune system to identify cancer cells

Researchers have identified a highly specific pathway that causes inflammation in lung tissue

Adult, or post-natal, stem cells have the same ability as embryonic stem cells to multiply

Researchers successfully treat laboratory model of a lysosomal storage disease called GM1

Adult, or post-natal, stem cells have the same ability as embryonic stem cells to multiply

New research tool replicates extreme environmental conditions to help understand the human body's response to everyday stresses

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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