Central Nervous System News and Research

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Galderma, Astrazeneca collaborate to develop new compounds for dermatological disorders

AstraZeneca and Galderma Pharma S.A., a global speciality pharmaceutical company focused on dermatology, today announced they have entered into a R&D collaboration to develop new treatments for dermatological conditions including psoriasis, acne and atopic dermatitis which significantly affect the health and quality of life for millions of people worldwide.

7 Mar 2011

Scientists detail role of TDP-43 in ALS pathology

Amyotrophic lateral sclerosis, known as ALS or more popularly, Lou Gehrig's disease, is a notorious neurodegenerative condition characterized by the progressive deterioration of brain and spinal cord neurons, resulting in the gradual but catastrophic loss of muscle control and ultimately, death.

5 Mar 2011

Researchers investigate why immune system is blunted after spinal cord injury

Mobility is a challenge for spinal cord injured patients. Infection is another. Adam Thrasher, assistant professor of health and human performance, says infection is the leading cause of death for people living with spinal cord injuries for two years or more.

4 Mar 2011

Few primary care physicians pay adequate attention to patients taking prescription opioid drugs

Few primary care physicians pay adequate attention to patients taking prescription opioid drugs — despite the potential for abuse, addiction and overdose, according to a new study by researchers at Albert Einstein College of Medicine of Yeshiva University.

4 Mar 2011

New discovery in glioma-associated metabolic changes

Metabolon, Inc., the leader in metabolomics, biomarker discovery and analysis, announces the publication of "Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome", in The Proceedings of the National Academy of Sciences.

3 Mar 2011

ITI, Takeda collaborate to develop and commercialize PDE1 inhibitors for schizophrenia

Intra-Cellular Therapies, Inc. ("ITI") and Takeda Pharmaceutical Company Limited, today announced that they have entered into an exclusive collaboration to develop and commercialize selective phosphodiesterase type 1 (PDE1) inhibitors, discovered by ITI, for the treatment of cognitive impairment associated with schizophrenia. This agreement is targeted worldwide, but ITI has retained the option to co-promote with Takeda in the United States.

3 Mar 2011

Scientists discover specific type of human cell to treat spinal cord injuries

For the first time, scientists discovered that a specific type of human cell, generated from stem cells and transplanted into spinal cord injured rats, provide tremendous benefit, not only repairing damage to the nervous system but helping the animals regain locomotor function as well.

2 Mar 2011

Experimental drug may help preserve neurological function in survivors of sudden cardiac arrest

An experimental drug that targets a brain system that controls inflammation might help preserve neurological function in people who survive sudden cardiac arrest, new research suggests.

2 Mar 2011

Scientists discover lead contamination in ceramic cookware sold in Philadelphia's Chinatown

Recently, a research team from the Department of Emergency Medicine at Jefferson Medical College of Thomas Jefferson University discovered an alarming amount of lead contamination in ceramic cooking and eating utensils sold in Philadelphia's Chinatown.

1 Mar 2011

Cummings School granted U.S. Patent for antibody-based treatment against Hemolytic Uremic Syndrome

Researchers at the Cummings School of Veterinary Medicine have received U.S. patent approval for an antibody-based treatment for Hemolytic Uremic Syndrome (HUS), a potentially fatal outcome of E. coli poisoning and the leading cause of kidney failure in children.

1 Mar 2011

Research uncovers new details about protein interactions in retina

Science fiction novelist and scholar Issac Asimov once said, "The most exciting phrase to hear in science, the one that heralds new discoveries, is not 'Eureka!' but 'That's funny.' " This recently rang true for an international team of researchers when they observed something they did not expect.

1 Mar 2011

Cryo-Cell fiscal 2010 net income increases to $3.4 million

Cryo-Cell International, Inc., one of the world's largest and most established family cord blood banks and an industry leader of innovative stem cell solutions, today announced results for its fiscal year 2010.

28 Feb 2011

Rexahn's novel anti-cancer quinoxalinyl-piperazine compounds granted European patent

Rexahn Pharmaceuticals, Inc., a clinical stage pharmaceutical company commercializing potential best in class oncology and CNS therapeutics, today announced that the European Patent Office has granted European patent No. 1819698 to Rexahn for its novel anti-cancer quinoxalinyl-piperazine compounds.

28 Feb 2011

AHRQ: $52.2 billion spent on prescription drugs for treatment of metabolic conditions during 2008

Insurers and consumers spent $52.2 billion on prescription drugs in 2008 for outpatient treatment of metabolic conditions such as diabetes and elevated cholesterol, according to the latest News and Numbers from the Agency for Healthcare Research and Quality.

28 Feb 2011

Lyme’s disease and chronic fatigue syndrome biomarkers found

A new study shows that spinal fluid can be used to detect proteins that help distinguish patients with Lyme disease from those with chronic fatigue syndrome.

27 Feb 2011

PACAP hormone levels linked to post-traumatic stress disorder

High blood levels of a hormone produced in response to stress are linked to post-traumatic stress disorder in women but not men, a study from researchers at Emory University and the University of Vermont has found.

25 Feb 2011

Study findings support therapeutic approach for common form of MS

In an effort to develop therapeutic remedies for multiple sclerosis, scientists debate two possible interventional approaches - but they're on opposite sides of the spectrum. Researchers at Wayne State University's School of Medicine, however, have reached a definitive conclusion as to which approach is correct, putting an end to a long-disputed issue.

24 Feb 2011

New research: Spinal fluid proteins can differentiate nPTLS from Chronic Fatigue Syndrome

Patients who suffer from Neurologic Post Treatment Lyme disease and those with the Chronic Fatigue Syndrome report similar symptoms. However unique proteins discovered in spinal fluid can distinguish those two groups from one another and also from people in normal health, according to new research conducted by a team led by Steven E. Schutzer, MD, of the University of Medicine and Dentistry of New Jersey - New Jersey Medical School, and Richard D. Smith, Ph.D., of Pacific Northwest National Laboratory.

24 Feb 2011

ISCTM 7th annual meeting to discuss drug development based on amyloid hypothesis of Alzheimer's disease

Continuing in their mission to promote advances in the development and use of CNS therapeutic agents, the International Society for CNS Clinical Trials and Methodology (ISCTM) met February 21, 2011 in Washington, D.C. to discuss one of the most important issues facing the field today.

23 Feb 2011

Swedish neuroscientist demonstrates how brain produces sense of ownership of the body

Leave your body and shake hands with yourself, gain an extra limb or change into a robot for a while. Swedish neuroscientist Henrik Ehrsson has demonstrated that the brain's image of the body is negotiable. Applications stretch from touch-sensitive prostheses to robotics and virtual worlds.

21 Feb 2011

Central Nervous System News and Research

Galderma, Astrazeneca collaborate to develop new compounds for dermatological disorders

Scientists detail role of TDP-43 in ALS pathology

Researchers investigate why immune system is blunted after spinal cord injury

Few primary care physicians pay adequate attention to patients taking prescription opioid drugs

New discovery in glioma-associated metabolic changes

ITI, Takeda collaborate to develop and commercialize PDE1 inhibitors for schizophrenia

Scientists discover specific type of human cell to treat spinal cord injuries

Experimental drug may help preserve neurological function in survivors of sudden cardiac arrest

Scientists discover lead contamination in ceramic cookware sold in Philadelphia's Chinatown

Cummings School granted U.S. Patent for antibody-based treatment against Hemolytic Uremic Syndrome

Research uncovers new details about protein interactions in retina

Cryo-Cell fiscal 2010 net income increases to $3.4 million

Rexahn's novel anti-cancer quinoxalinyl-piperazine compounds granted European patent

AHRQ: $52.2 billion spent on prescription drugs for treatment of metabolic conditions during 2008

Lyme’s disease and chronic fatigue syndrome biomarkers found

PACAP hormone levels linked to post-traumatic stress disorder

Study findings support therapeutic approach for common form of MS

New research: Spinal fluid proteins can differentiate nPTLS from Chronic Fatigue Syndrome

ISCTM 7th annual meeting to discuss drug development based on amyloid hypothesis of Alzheimer's disease

Swedish neuroscientist demonstrates how brain produces sense of ownership of the body

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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