Central Nervous System News and Research

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Novel molecular link between vitamin B12 and multiple sclerosis revealed in astrocytes

For decades, scientists have noted an intriguing similarity between a deficiency in vitamin B12 – an essential nutrient that supports healthy development and functioning of the central nervous system (CNS) – and multiple sclerosis (MS), a chronic disease in which the body's immune system attacks the CNS and which can produce neurodegeneration.

11 Dec 2023

Targeted therapy reduces markers of disease burden, improves symptoms for patients with nonadvanced system mastocytosis

The targeted therapy bezuclastinib was safe and rapidly reduced markers of disease burden while also improving symptoms for patients with a rare blood disorder called nonadvanced system mastocytosis, according to results of the Phase II SUMMIT trial reported by researchers at The University of Texas MD Anderson Cancer Center.

11 Dec 2023

Study provides a better understanding of how the brain responds to injuries

A new study published in Proceedings of the National Academy of Sciences Nexus provides a better understanding of how the brain responds to injuries.

11 Dec 2023

Study explores the intricate gut-brain-liver connection and its impact on health

Study reviews the gut-brain-liver axis, revealing the complex interplay between these organs in health and disease and the implications for therapeutic interventions, focusing on how gut microbiota affects liver and brain health.

10 Dec 2023

Immunoregulatory nanomedicines for the prevention and treatment of respiratory diseases

Study explores immunoregulatory nanomedicines for respiratory infections, highlighting their potential in enhancing treatment outcomes and vaccine efficacy.

7 Dec 2023

EU funds the international "BEHIND-MS" consortium to tackle multiple sclerosis

Multiple sclerosis (MS), an inflammatory disease of the central nervous system, affects more than 1 million people in Europe and an estimated 2.8 million worldwide.

7 Dec 2023

New drug combo fights breast cancer with brain metastases

A combination of two HER2-targeted drugs, tucatinib (Tukysa) and trastuzumab emtansine (Kadcyla, T-DM1), extended progression-free survival among patients with unresectable locally advanced or metastatic HER2-positive breast cancer, compared with T-DM1 alone, according to results from the HER2CLIMB-02 trial presented at the San Antonio Breast Cancer Symposium, held December 5-9, 2023.

6 Dec 2023

Targeting Alzheimer's with cell-specific genetics

Developing treatments for Alzheimer's disease (AD) is difficult because complex underlying mechanisms drive different types of cells that may contribute to the disorder.

5 Dec 2023

Does tinnitus cause hearing loss in normal hearing individuals?

Whether cochlear neural degeneration occurs in normal-hearing individuals with tinnitus.

4 Dec 2023

Exploring 'food noise': Study sheds light on eating thoughts and obesity treatment breakthroughs

Study delves into the concept of 'food noise,' referring to persistent thoughts about eating, and assesses its impact on eating behaviors and obesity treatments. It explores how GLP-1RAs, a class of drugs used for weight management, might influence food cue reactivity, potentially offering new insights into obesity treatment and the psychological aspects of eating behaviors.

30 Nov 2023

Insilico Medicine hosts three webinars to unveil latest technology breakthroughs

Insilico Medicine ("Insilico"), an artificial intelligence (AI)-driven, clinical stage biotechnology company and leader in AI drug discovery platform technology, is hosting three webinars unveiling its latest technology breakthroughs Nov. 28-30, 2023.

29 Nov 2023

Salk scientists uncover mechanism for repairing damaged nerves during peripheral neuropathy

Each year in the United States there are more than 3 million cases of peripheral neuropathy, wherein nerves outside of the brain and spinal cord are damaged and cause pain and loss of feeling in the affected areas.

28 Nov 2023

Abnormal myelin, not loss of myelin, may drive axon degeneration in myelin diseases

Myelin is an insulating sheath around axons - the processes connecting nerve cells - that is mostly composed of lipids and proteins.

28 Nov 2023

Study identifies how three novel genes cause neurodevelopmental disorders

An international study group led by researchers of Children's Hospital of Philadelphia (CHOP) have identified how three novel genes cause neurodevelopmental disorders.

28 Nov 2023

New cortex organoids more accurately represent the human brain

Essential features of the cortex, an important part of the human brain and its development, are more accurately captured in organoids generated by researchers of the Princess Máxima Center for pediatric oncology and the Hubrecht Institute.

28 Nov 2023

Researchers take step toward developing cell therapy treatment for MS

An international team has shown that the injection of a type of stem cell into the brains of patients living with progressive multiple sclerosis (MS) is safe, well tolerated and has a long-lasting effect that appears to protect the brain from further damage.

27 Nov 2023

Pigeon virus causes fatal neurological disease in young leukemia patient

A case report details a fatal neurologic disease in an immunocompromised toddler caused by pigeon avian paramyxovirus, underscoring the effectiveness of metagenomic testing in diagnosing complex infectious diseases.

19 Nov 2023

Curcumin boosts brain delivery of HIV drug, curbing inflammation and oxidative stress

Study shows curcumin enhances antiretroviral delivery and reduces inflammation and oxidative stress in HIV, offering potential improvements in treating HIV-associated neurocognitive disorders.

16 Nov 2023

Does regular cannabis use affect motor skills?

A study in Human Brain Mapping reveals that regular cannabis use alters the neural dynamics of motor control, showing that while cannabis users perform tasks with similar accuracy and reaction time as non-users, their brains exhibit stronger β-ERD responses during task execution, potentially indicating compensatory neural mechanisms.

15 Nov 2023

UMass Lowell researchers study gut microbiome's connection to neurodegenerative diseases

Researchers at UMass Lowell's Zuckerberg College of Health Sciences are exploring how the gut microbiome contributes to the risk of Parkinson's and Alzheimer's diseases.

15 Nov 2023

Central Nervous System News and Research

Novel molecular link between vitamin B12 and multiple sclerosis revealed in astrocytes

Targeted therapy reduces markers of disease burden, improves symptoms for patients with nonadvanced system mastocytosis

Study provides a better understanding of how the brain responds to injuries

Study explores the intricate gut-brain-liver connection and its impact on health

Immunoregulatory nanomedicines for the prevention and treatment of respiratory diseases

EU funds the international "BEHIND-MS" consortium to tackle multiple sclerosis

New drug combo fights breast cancer with brain metastases

Targeting Alzheimer's with cell-specific genetics

Does tinnitus cause hearing loss in normal hearing individuals?

Exploring 'food noise': Study sheds light on eating thoughts and obesity treatment breakthroughs

Insilico Medicine hosts three webinars to unveil latest technology breakthroughs

Salk scientists uncover mechanism for repairing damaged nerves during peripheral neuropathy

Abnormal myelin, not loss of myelin, may drive axon degeneration in myelin diseases

Study identifies how three novel genes cause neurodevelopmental disorders

New cortex organoids more accurately represent the human brain

Researchers take step toward developing cell therapy treatment for MS

Pigeon virus causes fatal neurological disease in young leukemia patient

Curcumin boosts brain delivery of HIV drug, curbing inflammation and oxidative stress

Does regular cannabis use affect motor skills?

UMass Lowell researchers study gut microbiome's connection to neurodegenerative diseases

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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