Chagas Disease News and Research

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Chagas (pronounced SHA-gus) disease is named after the Brazilian physician Carlos Chagas, who discovered it in 1909. It is caused by the parasite Trypanosoma cruzi, which is transmitted to animals and people by insect vectors that are found only in the Americas (mainly, in rural areas of Latin America where poverty is widespread). Chagas disease (T. cruzi infection) is also referred to as American trypanosomiasis.

People can become infected in various ways. In Chagas-endemic areas, the main way is through vectorborne transmission. The insect vectors are called triatomine bugs. These blood-sucking bugs get infected by biting an infected animal or person. Once infected, the bugs pass T. cruzi parasites in their feces. The bugs are found in houses made from materials such as mud, adobe, straw, and palm thatch. During the day, the bugs hide in crevices in the walls and roofs. During the night, when the inhabitants are sleeping, the bugs emerge. Because they tend to feed on people’s faces, triatomine bugs are also known as “kissing bugs.” After they bite and ingest blood, they defecate on the person. The person can become infected if T. cruzi parasites in the bug feces enter the body through mucous membranes or breaks in the skin. The unsuspecting, sleeping person may accidentally scratch or rub the feces into the bite wound, eyes, or mouth.
New ground-breaking initiative aims to find new treatments for leishmaniasis and Chagas disease

New ground-breaking initiative aims to find new treatments for leishmaniasis and Chagas disease

GHIT Fund expands investments in leishmaniasis, diagnostic tests

GHIT Fund expands investments in leishmaniasis, diagnostic tests

Southern Indiana to be oasis free from Lyme disease, finds Indiana University researcher

Southern Indiana to be oasis free from Lyme disease, finds Indiana University researcher

WHO calls on experts, social media to follow best practices in naming new human infectious diseases

WHO calls on experts, social media to follow best practices in naming new human infectious diseases

WHO issues best practices for naming new human infectious diseases

WHO issues best practices for naming new human infectious diseases

Cepheid, FIND announce receipt of CE-IVD status for Xpert HIV-1 Qual test

Cepheid, FIND announce receipt of CE-IVD status for Xpert HIV-1 Qual test

GHTC report confronts key challenge of renewing US leadership in global health technology

GHTC report confronts key challenge of renewing US leadership in global health technology

WHO urges affected countries to increase investment in tackling neglected tropical diseases

WHO urges affected countries to increase investment in tackling neglected tropical diseases

Penn, UGA scientists awarded new contract to develop genome database for microbial pathogens

Penn, UGA scientists awarded new contract to develop genome database for microbial pathogens

DNDi awarded USAID grant to develop new treatments for river blindness, elephantiasis

DNDi awarded USAID grant to develop new treatments for river blindness, elephantiasis

Bayer, DNDi sign first agreement to develop new oral treatment for onchocerciasis

Bayer, DNDi sign first agreement to develop new oral treatment for onchocerciasis

Mymetics' innovative HIV vaccine candidate to enter new preclinical trial

Mymetics' innovative HIV vaccine candidate to enter new preclinical trial

Prevalence of NTDs in Latin American countries presents opportunity for US foreign policy

Prevalence of NTDs in Latin American countries presents opportunity for US foreign policy

Scientists, health officials and artists working on apps to identify disease-carrying insects

Scientists, health officials and artists working on apps to identify disease-carrying insects

Celgene Global Health, DNDi expand partnership to identify new drug candidates for NTDs

Celgene Global Health, DNDi expand partnership to identify new drug candidates for NTDs

New research identifies novel cellular factors vital for CCHFV infection

New research identifies novel cellular factors vital for CCHFV infection

GHIT Fund announces new grants to tackle malaria, chagas disease and dengue

GHIT Fund announces new grants to tackle malaria, chagas disease and dengue

Fogarty receives three grants for research focused on biodiversity conservation

Fogarty receives three grants for research focused on biodiversity conservation

Vaccine for Chagas disease expected to be available within the next three years

Vaccine for Chagas disease expected to be available within the next three years

Researchers to develop global database on situation and evolution of Chagas disease

Researchers to develop global database on situation and evolution of Chagas disease

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