Chagas Disease News and Research

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Chagas (pronounced SHA-gus) disease is named after the Brazilian physician Carlos Chagas, who discovered it in 1909. It is caused by the parasite Trypanosoma cruzi, which is transmitted to animals and people by insect vectors that are found only in the Americas (mainly, in rural areas of Latin America where poverty is widespread). Chagas disease (T. cruzi infection) is also referred to as American trypanosomiasis.

People can become infected in various ways. In Chagas-endemic areas, the main way is through vectorborne transmission. The insect vectors are called triatomine bugs. These blood-sucking bugs get infected by biting an infected animal or person. Once infected, the bugs pass T. cruzi parasites in their feces. The bugs are found in houses made from materials such as mud, adobe, straw, and palm thatch. During the day, the bugs hide in crevices in the walls and roofs. During the night, when the inhabitants are sleeping, the bugs emerge. Because they tend to feed on people’s faces, triatomine bugs are also known as “kissing bugs.” After they bite and ingest blood, they defecate on the person. The person can become infected if T. cruzi parasites in the bug feces enter the body through mucous membranes or breaks in the skin. The unsuspecting, sleeping person may accidentally scratch or rub the feces into the bite wound, eyes, or mouth.
New tools for neglected diseases: an interview with Dr. BT Slingsby, CEO, GHIT Fund

New tools for neglected diseases: an interview with Dr. BT Slingsby, CEO, GHIT Fund

PLOS and DNDi to launch collection of neglected tropical diseases at 10-year anniversary of DNDi

PLOS and DNDi to launch collection of neglected tropical diseases at 10-year anniversary of DNDi

New paper highlights correlations between changes in natural systems and potential health outcomes

New paper highlights correlations between changes in natural systems and potential health outcomes

GHIT Fund makes new investments in potential treatments for malaria, tuberculosis and Chagas disease

GHIT Fund makes new investments in potential treatments for malaria, tuberculosis and Chagas disease

GHIT Fund grants US$5.7 million to six global partnerships working on vaccines against malaria

GHIT Fund grants US$5.7 million to six global partnerships working on vaccines against malaria

Study finds persistent deficiency in new therapeutics for neglected diseases

Study finds persistent deficiency in new therapeutics for neglected diseases

University of Warwick professor wins Discovery STAR Award to identify new treatment for Chagas disease

University of Warwick professor wins Discovery STAR Award to identify new treatment for Chagas disease

DFID awards 5-year grant to DNDi to advance research and development for neglected diseases

DFID awards 5-year grant to DNDi to advance research and development for neglected diseases

Immunetics receives FDA clearance for BacTx rapid test for bacteria in apheresis platelets

Immunetics receives FDA clearance for BacTx rapid test for bacteria in apheresis platelets

DNDi and Institut Pasteur Korea collaborates to spur fight against neglected diseases

DNDi and Institut Pasteur Korea collaborates to spur fight against neglected diseases

WHO includes new paediatric therapeutic options to EMLc

WHO includes new paediatric therapeutic options to EMLc

WHO's new HIV treatment guidelines call for immediate ART for HIV-infected children

WHO's new HIV treatment guidelines call for immediate ART for HIV-infected children

Sustained engagement, partnership needed to implement new treatments for neglected diseases

Sustained engagement, partnership needed to implement new treatments for neglected diseases

New LAMP malaria test to improve diagnosis for imported UK cases

New LAMP malaria test to improve diagnosis for imported UK cases

AfriCoLeish receives grant from European Union to test new treatments for kala-azar

AfriCoLeish receives grant from European Union to test new treatments for kala-azar

Documentary film examines Chagas disease in Argentina

Documentary film examines Chagas disease in Argentina

New Japan-driven initiative to accelerate research, development innovation for neglected diseases

New Japan-driven initiative to accelerate research, development innovation for neglected diseases

Student coalition ranks research universities' spending and activities on neglected diseases, other illnesses

Student coalition ranks research universities' spending and activities on neglected diseases, other illnesses

New Pope will need to consider burden of NTDs

New Pope will need to consider burden of NTDs

DNDi receives 2013 BBVA Foundation Frontiers of Knowledge and Culture Award

DNDi receives 2013 BBVA Foundation Frontiers of Knowledge and Culture Award