Chemical Messenger News and Research

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New class of drugs to repair psychiatric disorders

“Smart” drugs capable of targeting specific brain cells to control psychiatric disorders such as autism and schizophrenia may be ready for early clinical trials within three years, with the launch of a $1.5 million project to take place at the Brain Research Centre (BRC)

29 Nov 2004

Dementia patients receiving long-term treatment with Reminyl may be able to stay at home for longer compared

Shire Pharmaceuticals Group has announced that Dementia patients receiving long-term treatment with Reminyl (more than 36 months) may be able to stay at home for longer compared to those receiving treatment for shorter periods of time.

10 Nov 2004

alpha4 may prove to be useful target for smoking addiction therapies

Nicotine is responsible for more than four million smoking-related deaths each year. Yet people still smoke. Why? One reason is the stranglehold of addiction, started when nicotine enhances the release of a neurotransmitter called dopamine

4 Nov 2004

Drinking regular cuppas could help improve your memory

Results of laboratory tests by a team from the University of Newcastle upon Tyne found that green and black tea inhibit the activity of certain enzymes in the brain which are associated with memory.

25 Oct 2004

Discovery of fundamental mechanism within cells that link obesity and type 2 diabetes

Researchers from the Harvard School of Public Health have discovered what they believe is the fundamental mechanism within cells that links two fast-rising public health threats: obesity and Type 2 diabetes.

18 Oct 2004

Highly concentrated solution of chemical messengers could block male to female HIV transmission

Researchers in the U.S have shown that it may be possible to block the transmission of the HIV virus from a man to a woman by using a highly concentrated solution of chemical messengers that attract white blood cells to the site of infection.

16 Oct 2004

Scientists develop rapid-fire tests for botulinum toxin

Scientists at the University of Wisconsin-Madison have developed a pair of rapid-fire tests for botulinum toxin, a feat that could underpin new technologies to thwart bioterrorism and spur the development of agents to blunt the toxic action of the world's most poisonous substance.

29 Sep 2004

New gene therapy technique may help treat Alzheimer's disease

Investigators at Rush University Medical Center have successfully initiated a new technique that uses gene therapy to deliver nerve growth factor into regions of the brain where neurons are degenerating, in order to prevent cell death and reverse cell atrophy, two hallmarks of Alzheimer's disease.

21 Sep 2004

Relationship between brain chemical messenger glutamate and schizophrenia traits

Researchers at the NIH's National Institute of Mental Health (NIMH) have identified a relationship between a small section of one gene, the brain chemical messenger glutamate, and a collection of traits known to be associated with schizophrenia.

15 Aug 2004

Gene responsible for management of glutamate is a promising candidate in determining risk for schizophrenia

Researchers at the National Institute of Mental Health have identified a relationship between a small section of one gene, the brain chemical messenger glutamate, and a collection of traits known to be associated with schizophrenia.

11 Aug 2004

New screening tool prevents wrong patients from receiving Parkinson's surgery

The allure of a new brain surgery technique to relieve the stiffness and shaking caused by Parkinson’s disease may lead to unnecessary operations, University of Florida researchers say, but a new screening tool they developed could prevent potentially dangerous procedures.

9 Aug 2004

Overactive brain circuit brings on depression

A brain imaging study by the NIH's National Institute of Mental Health (NIMH) has found that an emotion-regulating brain circuit is overactive in people prone to depression – even when they are not depressed.

5 Aug 2004

Switches in the brain that tell the body to stop eating and start burning calories

A Brown-led research team has discovered a pair of universal switches in the brain that tell the body to stop eating and start burning calories.

3 Aug 2004

Botox approved as treatment for severe underarm sweating

The FDA has approved Botulinum Toxin Type A (Botox) to treat severe underarm sweating known as “primary axillary hyperhidrosis” that cannot be managed by topical agents such as prescription antiperspirants. Botox has already been approved for several other purposes.

20 Jul 2004

Identification of a naturally occurring genetic difference that controls the production of serotonin in the brain

Researchers at Duke University Medical Center have provided the first direct evidence in mice for the role of an enzyme that specifically controls the production of serotonin in the brain.

8 Jul 2004

Khat plant may create next men’s fertility wonder drug

Now, researchers at the Centre for Reproduction, Endocrinology and Diabetes at King’s College London, UK, have studied the effects of PPAs on mouse and human sperm and found the first evidence that they stimulate the final stage of sperm maturation (capacitation) when sperm develop the ability to fertilize an egg.

28 Jun 2004

Marijuana/Cannabis causes transient schizophrenia-like symptoms

The principal active ingredient in marijuana causes transient schizophrenia-like symptoms ranging from suspiciousness and delusions to impairments in memory and attention, according to a Yale research study.

15 Jun 2004

Genes that allow nerve cells to communicate may have come from bacteria eons ago

Some of the genes that allow nerve cells and some other types of cells to send elaborate chemical messages to each other appear to have been transferred to animals or their immediate ancestors from bacteria eons ago.

2 Jun 2004

Small, frequent doses of caffeine best strategy for staying awake

Caffeine is the world's most widely-used stimulant yet, scientists still do not know exactly how it staves off sleep. Researchers at Brigham and Women's Hospital, Harvard Medical School and other institutions have now discovered that caffeine works by thwarting one of two interacting physiological systems that govern the human sleep-wake cycle.

11 May 2004

Fat fighting undermined by over active eating pacemaker

They have revealed a set of pacemaker nerve cells in the brain that appear to underlie the drive to feed which itself feeds on a complex web of signals.