Cholinesterase Inhibitor News and Research

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Since the introduction of the first cholinesterase inhibitor (ChEI) in 1997, most clinicians and probably most patients would consider the cholinergic drugs, donepezil, galantamine and rivastigmine, to be the first line pharmacotherapy for mild to moderate Alzheimer's disease. The drugs have slightly different pharmacological properties, but they all work by inhibiting the breakdown of acetylcholine, an important neurotransmitter associated with memory, by blocking the enzyme acetylcholinesterase.
Dual treatment of incontinence and dementia associated with functional decline

Dual treatment of incontinence and dementia associated with functional decline

Dual treatment of incontinence and dementia associated with functional decline

Dual treatment of incontinence and dementia associated with functional decline

Cholinesterase inhibitors do not seem to delay Alzheimer disease

Cholinesterase inhibitors do not seem to delay Alzheimer disease

From successful aging to severe dementia

From successful aging to severe dementia

New drug may restore memory with Alzheimer's disease

New drug may restore memory with Alzheimer's disease

Electroacupuncture on the anterior forearm may help gastroesophageal reflux disease symptoms

Electroacupuncture on the anterior forearm may help gastroesophageal reflux disease symptoms

Donepezil no better than placebo to treat behavioural symptoms of Alzheimer's

Donepezil no better than placebo to treat behavioural symptoms of Alzheimer's

New 'patch' drug therapy for Alzheimer's has fewer side effects

New 'patch' drug therapy for Alzheimer's has fewer side effects

Improving care for Alzheimer disease sufferers

Improving care for Alzheimer disease sufferers

Aricept, Razadyne and Exelon can help people with mild Alzheimer's

Aricept, Razadyne and Exelon can help people with mild Alzheimer's

Blue-green algae shows promise as a natural weapon against Alzheimer's

Blue-green algae shows promise as a natural weapon against Alzheimer's

Potential beneficial effect of copper orotate

Potential beneficial effect of copper orotate

Clinical diagnosis of Alzheimer's may be delayed

Clinical diagnosis of Alzheimer's may be delayed

Atorvastatin slows down mental decline and improves depressive symptoms in people with Alzheimer’s disease

Atorvastatin slows down mental decline and improves depressive symptoms in people with Alzheimer’s disease

Trial of new type of drug that attacks amyloid

Trial of new type of drug that attacks amyloid

Effectiveness of gingko to treat early dementia

Effectiveness of gingko to treat early dementia

Drug used to treat schizophrenia and other psychotic disorders appears effective at treating Alzheimer’s disease

Drug used to treat schizophrenia and other psychotic disorders appears effective at treating Alzheimer’s disease

People who have early stage Alzheimer's disease could be more capable of learning than previously thought

People who have early stage Alzheimer's disease could be more capable of learning than previously thought

Canadian Alzheimer Society responds to donepezil study

Canadian Alzheimer Society responds to donepezil study

Most Alzheimer's drugs don't work

Most Alzheimer's drugs don't work