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DNA aptamers: A versatile tool for regenerative medicine and beyond

Generating specific cell lineages from induced pluripotent stem cells and embryonic stem cells is the holy grail of regenerative medicine.

10 Oct 2023

Study discovers epigenetic regulator's critical role in mitochondrial metabolism

The intricate control of cellular metabolism relies on the coordinated and harmonious interplay between the nucleus and mitochondria.

9 Oct 2023

Altering certain molecular interactions could yield new strategies for treating prostate cancer

Research led by Mays Cancer Center at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) has discovered that altering certain molecular interactions could yield new strategies for treating prostate cancer and related diseases.

6 Oct 2023

New insights into how neutrophils fight Candida albicans infection

Umeå University researchers, Sweden, unveil how the most common white blood cells, neutrophils, counter Candida albicans toxin stopping its tracks.

5 Oct 2023

CRISPR gene editing study provides insights into how autism gene affects brain development

Researchers have used CRISPR gene editing, stem cells and human neurons to study the impact of a gene that is commonly mutated in autism.

5 Oct 2023

Could infants' robust immune responses reshape future vaccination strategies?

Utilizing next-gen sequencing techniques, researchers analyzed infants' immune responses to infections, uncovering a predominant innate immune activation unlike adults and older children. This insight could steer child vaccination research and pediatric infection management strategies, potentially revolutionizing infant healthcare.

3 Oct 2023

Ginger shows promise as a natural defense against autoimmune diseases

Comprehensive study reveals that whole ginger extracts have a significant impact on inhibiting neutrophil hyperactivity, a key factor in autoimmune diseases like APS and lupus. Consuming ginger for just a week showed promising results in both animal models and human trials, positioning it as a natural and affordable treatment option for a range of autoimmune disorders.

2 Oct 2023

Fatty liver disease susceptibility: study identifies interaction between estrogen receptor and genetic variant in women

Researchers pursued evidence of whether the interaction between the patatin-like phospholipase domain-containing 3 p.I148M variant and the female sex at the genetic and molecular level explains why premenopausal women remain protected against fatty liver disease, while a rapidly progressive disease ensues in some peri- and postmenopausal women.

28 Sep 2023

Key player in ovarian cancer may have implications for PCOS

Researchers explore the involvement and altered expression of BBOX1-AS1 and microRNA-19b in polycystic ovary syndrome.

26 Sep 2023

Researchers identify a rare cause of male infertility and discover a potential cure

Researchers investigated the genetic underpinning of asthenozoospermia, the leading cause of male fertility.

18 Sep 2023

Unlocking the secret drivers of deadly pancreatic cancer: New target offers hope for treatment

Researchers identify a super-enhancer-regulated RNA-binding protein cascade that drives the growth of pancreatic ductal adenocarcinoma, a deadly form of pancreatic cancer. The discovery offers a promising new avenue for targeted therapy, potentially sidestepping severe side effects associated with other treatments.

10 Sep 2023

A comprehensive online resource allows for the exploration of interactions between mutational signatures and topographical features across human cancer

An online resource for studying the relationship between mutational signatures and topographical characteristics across human cancer.

28 Aug 2023

Chromatin News and Research

DNA aptamers: A versatile tool for regenerative medicine and beyond

Study discovers epigenetic regulator's critical role in mitochondrial metabolism

Altering certain molecular interactions could yield new strategies for treating prostate cancer

New insights into how neutrophils fight Candida albicans infection

CRISPR gene editing study provides insights into how autism gene affects brain development

Could infants' robust immune responses reshape future vaccination strategies?

Ginger shows promise as a natural defense against autoimmune diseases

Fatty liver disease susceptibility: study identifies interaction between estrogen receptor and genetic variant in women

Key player in ovarian cancer may have implications for PCOS

Researchers identify a rare cause of male infertility and discover a potential cure

Unlocking the secret drivers of deadly pancreatic cancer: New target offers hope for treatment

A comprehensive online resource allows for the exploration of interactions between mutational signatures and topographical features across human cancer

The potential of targeting mitochondria-associated programmed cell death for age-related disease treatment

Disruption of FOXA2 expression in congenital hyperinsulinism: The role of chromosome 20p11.2 deletions

Scientists find way to 'press self-destruct button' in gastric cancer associated with Epstein-Barr Virus

UAB researchers identify cell-surface marker that indicates fate of T cells

How conversion between different types of cell death contributes to disease

The impact of epigenetic features on breast cancer treatment and outcomes

New PCNA inhibitor AOH1996 shows selective cancer cell killings and tumor suppression potential

Recent advances in the understanding of the role and mechanism of CCAR2 in cancer

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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