Chromatin News and Research

RSS

Study finds a new mammalian antiviral response pathway restricting poxviruses replication

In a recent study posted to the bioRxiv* preprint server, researchers identified a novel antiviral pathway different from the interferon (IFN) pathway that inhibited poxvirus(es) replication.

15 Feb 2023

Five teams awarded funding from the Starr Cancer Consortium to advance cancer research

Five teams led by Weill Cornell Medicine scientists have been awarded funding from the Starr Cancer Consortium in its 16th annual grant competition.

10 Feb 2023

UVA researchers discover a key trigger for non-alcoholic fatty liver disease

University of Virginia School of Medicine researchers have discovered a key trigger for non-alcoholic fatty liver disease, a mysterious condition that causes fat to build up in the liver for no clear reason.

9 Feb 2023

Scientists use next-generation protein degradation technology to study CTCF's role in transcription

CTCF is a critical protein known to play various roles in key biological processes such as transcription. Scientists at St. Jude Children's Research Hospital used a next-generation protein degradation technology to study CTCF.

26 Jan 2023

New method analyzes long-range interactions in the interactome

Researchers at the Josep Carreras Leukaemia Research Institute have developed a method to analyze long-range interactions in the DNA -the interactome- from a very low amount of starting material.

25 Jan 2023

Researchers review the association between endogenous retrovirus reactivation and aging

Researchers explored the role of endogenous retrovirus (ERV) reactivation in the aging process.

24 Jan 2023

DNA sequencing method detects where and how small molecule drugs interact with the targeted genome

Many life-saving drugs directly interact with DNA to treat diseases such as cancer, but scientists have struggled to detect how and why they work – until now.

23 Jan 2023

Study reveals how most-resistant pancreatic cancer cells defy treatment

Pancreatic cancer is the third deadliest cancer in the United States, after lung and colorectal, though far less common.

19 Jan 2023

Research explores the utility of epigenetically predicted BMI

DNA methylation is an accurate predictor of current BMI and a poor predictor of future BMI.

18 Jan 2023

The loss of epigenetic information accelerates the aging process

A new study in the journal Cell aimed to determine whether epigenetic changes are a cause of mammalian aging.

15 Jan 2023

Study uncovers a new role for Slit2 signaling in stimulating Ewing sarcoma growth

A new research paper was published in Genes & Cancer on December 14, 2022, entitled, "Slit2 signaling stimulates Ewing sarcoma growth."

13 Jan 2023

Study identifies LAP1 as a master regulator of nuclear envelope remodeling during melanoma progression

Researchers discovered that the elevated expression of LAP1, an inner nuclear membrane protein, helps metastatic melanoma cells surmount the physical challenges presented by tissue structure and the microenvironment during metastasis.

11 Jan 2023

Decade-long search in one-celled, fresh water dwelling organism solves puzzle involved in gene regulation

After an intrepid, decade-long search, Johns Hopkins Medicine scientists say they have found a new role for a pair of enzymes that regulate genome function and, when missing or mutated, are linked to diseases such as brain tumors, blood cancers and Kleefstra syndrome -; a rare genetic, neurocognitive disorder.

22 Dec 2022

Chromatin News and Research

Study finds a new mammalian antiviral response pathway restricting poxviruses replication

Five teams awarded funding from the Starr Cancer Consortium to advance cancer research

UVA researchers discover a key trigger for non-alcoholic fatty liver disease

Scientists use next-generation protein degradation technology to study CTCF's role in transcription

New method analyzes long-range interactions in the interactome

Researchers review the association between endogenous retrovirus reactivation and aging

DNA sequencing method detects where and how small molecule drugs interact with the targeted genome

Study reveals how most-resistant pancreatic cancer cells defy treatment

Research explores the utility of epigenetically predicted BMI

The loss of epigenetic information accelerates the aging process

Study uncovers a new role for Slit2 signaling in stimulating Ewing sarcoma growth

Study identifies LAP1 as a master regulator of nuclear envelope remodeling during melanoma progression

Decade-long search in one-celled, fresh water dwelling organism solves puzzle involved in gene regulation

Phenotypic plasticity may allow cancer cells to evade standard therapy

New insights into biophysical origins of the genome's organization inside the cell nucleus

First cell-type specific multiomic study of the HIV brain

Researchers identify a new target gene in pancreatic ductal adenocarcinoma

Scientists use single-cell multi-omics data to map disease regulatory circuits

What is the association between farnesoid X receptor inhibition and protection against COVID-19?

New spatial cell atlas of the developing human lung identifies 144 cell states

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

Latest Life Science News