Chromatography News and Research

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Chromatography in Greek means to ‘write with colors.’ It is a versatile separation technique developed in 1903 by Mikhail Tswett, a Russian botanist. He separated colorful plant pigments using a column of calcium carbonate. Ever since its discovery, chromatography has evolved as a powerful tool in the lab for the separation and identification of different compounds in a mixture.

Study shows how AF4-MALS-UV can separate and size large AAV aggregates

Postnova Analytics has published a new applications study that reports on how Asymmetric Flow Field Flow Fractionation (AF4) coupled with multi-angle light scattering (MALS) and Ultraviolet (UV) detectors can be used to quantify Adeno-Associated Virus (AAV) aggregation.

From Postnova Analytics 25 Sep 2019

New technique for police to quickly and safely test drug evidence

Scientists have demonstrated a way for police to quickly and safely test whether a baggie or other package contains illegal drugs without having to handle any suspicious contents directly.

17 Sep 2019

Atlas Antibodies presents QPrEST standards for absolute quantification of proteins using mass spectrometry

Atlas Antibodies AB, a leading supplier of advanced research reagents, announced today the introduction of pre-quantified QPrEST™ Protein Standards for absolute quantification of proteins in biological samples such as cell lysate and plasma using liquid chromatography (LC)–mass spectrometry (MS).

From Atlas Antibodies 16 Sep 2019

BIA Separations launches Cornerstone AAV Process Development Service to improve gene therapy production

BIA Separations, a leading bio-chromatography development and manufacturing company, today announced the introduction of CORNERSTONE AAV Process Development Service, a program of integrated process development services and novel technology designed to improve the robustness and yield of AAV-based gene therapy production, while improving the safety of therapeutic products.

12 Sep 2019

KNAUER joins industrial sustainability research project

Starting September 2019, KNAUER is now part of the EU funded IMPRESS research program, with the goal to advance the sustainable production of chemistry raw materials.

From KNAUER Wissenschaftliche Geräte GmbH 8 Sep 2019

Melatonin promises to help reduce bone loss in space flight

New research suggests that the problem of bone loss caused by microgravity conditions in space flight may be successfully treated using the time-tested drug melatonin. Melatonin increases the level of calcitonin in bone, which suppresses the bone-destroying activity of osteoclastic cells and helps maintain bone density.

4 Sep 2019

Using anion exchange chromatography and electrochemical detection for determination of carbohydrates

Carbohydrates are among the most widespread organic compounds in the living nature. As monosaccharides and di-saccharides, they primarily serve the direct supply of energy in the organism. In the form of oligomers or polymers, they are used more for storage of energy or information, or take over tasks as a structural element in cell walls, primarily of plants.

From KNAUER Wissenschaftliche Geräte GmbH 3 Sep 2019

EAF4 technology for separation and characterization of nanoplastics in the environment

Postnova Analytics has published a new application note that demonstrates the promise of Electrical Asymmetric Field Flow Fractionation (EAF4) technology for separation and characterization of nanoplastics in the environment.

From Postnova Analytics 29 Aug 2019

Smoking simulator captures synthetic cannabinoid combustion products

Researchers have developed a smoking simulator that enables the reliable detection of the combustion products formed when synthetic cannabinoids are smoked.

26 Aug 2019

New test reveals truth behind gluten-free labels

Many people have wondered whether the gluten-free labeling on their groceries was true. Now, scientists in Australia have come up with a way to identify the presence of specific glutens in rye that indicate the presence of this grain in foods labeled “gluten-free”. Gluten is already known to be present in wheat, barley and oats.

15 Aug 2019

Fatty foods increase CBD absorption, finds new research

With both marijuana and alcohol being legal in the US, researchers have found that an increasing proportion of people are using both drugs in combination. However, this is a risky thing to do, says a new study. The increased risk is largely due to the overlap of effects between the two separate drugs.

14 Aug 2019

New combination method improves characterization of polysaccharides

Postnova Analytics reports on a new method for the accurate molecular weight determination of complex polysaccharides (Chitosans) using asymmetric flow field flow fractionation (AF4) coupled with multi-angle light scattering (MALS) and differential refractive index (RI) detectors.

From Postnova Analytics 16 Jul 2019

Tomocube HT microscope enables label-free quantification of cellular lipid content

In a breakthrough for research fields as diverse as diabetes, atherosclerosis and biofuels, the mass, concentration, volume, and surface area of individual lipid droplets have been measured in live, unstained cells for the first time using a Tomocube Holotomography microscope.

From Tomocube Inc. 12 Jul 2019

Why Mattresses Could be a Health Threat to Sleeping Children

Researchers at the Israel Institute of Technology have found that children’s mattresses may represent a health hazard as they emit some dangerous pollutants at concerning levels overnight.

11 Jul 2019

Researchers develop new nanotheranostic system that solves many problems

Theranostics is an emerging field of medicine whose name is a combination of "therapeutics" and "diagnostics".

9 Jul 2019

Goat's milk-based formula good for infant's gut health

Researchers from RMIT’s lab analyzed goat’s milk formula and looked at the oligosaccharides present in it.

27 Jun 2019

Characterizing and Isolating (Bio)macromolecular Structures using MALS

In this interview, Albena Lederer, Head of the Polymer Separation Group at the Leibniz Institute for Polymer Research, talks to News-Medical Life Sciences about the techniques and methods used to understand and analyze polymers.

From Waters | Wyatt Technology 26 Jun 2019

Using Light Scattering to Characterize Protein-Nucleic Acid Interactions

Harnessing the interactions between DNA, RNA, and proteins holds much promise for detecting biomarkers, diagnosing disease, and improving cancer-targeting therapeutics. Quantifying these interactions is essential for understanding and controlling their biomolecular mechanisms.

From Waters | Wyatt Technology 26 Jun 2019

Stability Testing of Therapeutic Proteins using DLS and Machine Learning

PIPPI scientists from different fields are developing methodologies, tools, and databases to guide the rational formulation of robust protein-based therapeutics. Their overall goal is to develop a database to guide product formulation development.

From Waters | Wyatt Technology 26 Jun 2019