Chromosome 1 News and Research

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Humans normally have 46 chromosomes in each cell, divided into 23 pairs. Two copies of chromosome 1, one copy inherited from each parent, form one of the pairs. Chromosome 1 is the largest human chromosome, spanning about 247 million base pairs (the building blocks of DNA) and representing approximately 8 percent of the total DNA in cells.

Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 1 likely contains more than 3,000 genes.

Genes on chromosome 1 are among the estimated 20,000 to 25,000 total genes in the human genome.
Research aims to raise awareness of higher rate of testicular cancer in patients with DS

Research aims to raise awareness of higher rate of testicular cancer in patients with DS

New study maps human genome to healthy tissue functions and disease processes

New study maps human genome to healthy tissue functions and disease processes

Researchers use mixed realty viewer to visualize complex biological networks in 3D

Researchers use mixed realty viewer to visualize complex biological networks in 3D

Abnormalities of blood vessels in the brain may play major role in development of schizophrenia

Abnormalities of blood vessels in the brain may play major role in development of schizophrenia

Whitehead Institute scientists identify brain/body connection in genomic region linked to autism

Whitehead Institute scientists identify brain/body connection in genomic region linked to autism

Change in epigenetic gene regulation by imprinting can trigger preeclampsia, study shows

Change in epigenetic gene regulation by imprinting can trigger preeclampsia, study shows

Research findings can lead to new treatment for patients with fatal glandular cancer

Research findings can lead to new treatment for patients with fatal glandular cancer

Pediatric researchers discover gene variants related to aggressive form of neuroblastoma

Pediatric researchers discover gene variants related to aggressive form of neuroblastoma

Researchers discover ‘recycled’ genes in mammalian genome

Researchers discover ‘recycled’ genes in mammalian genome

Lesser-known gene appears to play greater role in Alzheimer's and dementia-related memory decline

Lesser-known gene appears to play greater role in Alzheimer's and dementia-related memory decline

Genome sequence cannot predict radiation resistance, say researchers

Genome sequence cannot predict radiation resistance, say researchers

Researchers develop model to explore hard-to-study mutations in human genome

Researchers develop model to explore hard-to-study mutations in human genome

Penn researchers find abnormally shortened telomeres in young DMD patients’ muscle stem cells

Penn researchers find abnormally shortened telomeres in young DMD patients’ muscle stem cells

Researchers find correlation between shorter telomeres and presence of heart failure

Researchers find correlation between shorter telomeres and presence of heart failure

Split-brain study using fruit fly provides better understanding of autism

Split-brain study using fruit fly provides better understanding of autism

Japanese scientists uncover new genetic marker for schizophrenia

Japanese scientists uncover new genetic marker for schizophrenia

UAB researchers reveal key role for RSF1 protein in silencing genes

UAB researchers reveal key role for RSF1 protein in silencing genes

Human ancestors responsible for transmitting ancient strains of herpesvirus, study finds

Human ancestors responsible for transmitting ancient strains of herpesvirus, study finds

Study sheds new light on gene fusion in bladder and brain cancer

Study sheds new light on gene fusion in bladder and brain cancer

Distinguishing biothreat look-alikes could aid biological surveillance

Distinguishing biothreat look-alikes could aid biological surveillance