Chromosome 16 News and Research

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Humans normally have 46 chromosomes in each cell, divided into 23 pairs. Two copies of chromosome 16, one copy inherited from each parent, form one of the pairs. Chromosome 16 spans about 89 million base pairs (the building blocks of DNA) and represents almost 3 percent of the total DNA in cells.

Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 16 likely contains between 850 and 1,200 genes.

Genes on chromosome 16 are among the estimated 20,000 to 25,000 total genes in the human genome.
Researchers identify new sarcoma familial risk gene

Researchers identify new sarcoma familial risk gene

Family genetic background essential for understanding autism progression

Family genetic background essential for understanding autism progression

Genes associated with autism interact to modulate variable symptoms of disease

Genes associated with autism interact to modulate variable symptoms of disease

New study identifies key role for particular gene in 16p11.2 deletion syndrome

New study identifies key role for particular gene in 16p11.2 deletion syndrome

Scientists identify treatments that may restore brain function to autism patients

Scientists identify treatments that may restore brain function to autism patients

Whitehead Institute scientists identify brain/body connection in genomic region linked to autism

Whitehead Institute scientists identify brain/body connection in genomic region linked to autism

Researchers describe how genetic mutations cause unnamed neurological disorder

Researchers describe how genetic mutations cause unnamed neurological disorder

Alterations in genomic region linked to risk of ASD have distinctive effects on cognition, study reports

Alterations in genomic region linked to risk of ASD have distinctive effects on cognition, study reports

Discovery could lead to better therapies for people with obsessive compulsive disorder

Discovery could lead to better therapies for people with obsessive compulsive disorder

Resistance to CD19 CAR T-cell therapy can be caused by CD19 splicing alterations

Resistance to CD19 CAR T-cell therapy can be caused by CD19 splicing alterations

Study uncovers new genetic variants linked to increased risk of testicular cancer

Study uncovers new genetic variants linked to increased risk of testicular cancer

Study on how maternal proteins help regulate initial cell divisions during early development

Study on how maternal proteins help regulate initial cell divisions during early development

Novel molecule inhibits cancer-causing transcription factors

Novel molecule inhibits cancer-causing transcription factors

Genomics researchers discover novel gene variants in childhood CVID

Genomics researchers discover novel gene variants in childhood CVID

Research may lead to future medical treatments for children with neurodevelopmental problems

Research may lead to future medical treatments for children with neurodevelopmental problems

Puzzle in breast cancer solved

Puzzle in breast cancer solved

Study examines links between parental obesity and risk of autism developmental in child

Study examines links between parental obesity and risk of autism developmental in child

Researchers identify genetic variants associated with Barrett's and esophageal cancer

Researchers identify genetic variants associated with Barrett's and esophageal cancer

Structural connectome maps reveal new details about agenesis of the corpus callosum

Structural connectome maps reveal new details about agenesis of the corpus callosum

NAP and SAL injection during pregnancy improve memory, learning tasks in offsprings

NAP and SAL injection during pregnancy improve memory, learning tasks in offsprings