Chromosome 17 News and Research

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Humans normally have 46 chromosomes in each cell, divided into 23 pairs. Two copies of chromosome 17, one copy inherited from each parent, form one of the pairs. Chromosome 17 spans about 79 million base pairs (the building blocks of DNA) and represents between 2.5 percent and 3 percent of the total DNA in cells.

Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 17 likely contains between 1,200 and 1,500 genes.

Genes on chromosome 17 are among the estimated 20,000 to 25,000 total genes in the human genome.
Unexpected connection found between feeding and memory centers of the brain

Unexpected connection found between feeding and memory centers of the brain

Study highlights opposite effects of gene following different types of environmental events

Study highlights opposite effects of gene following different types of environmental events

Scientists explore interactions between chromosomes 12 and 17

Scientists explore interactions between chromosomes 12 and 17

Genomic roots of ovarian tumors may arise in fallopian tubes, study suggests

Genomic roots of ovarian tumors may arise in fallopian tubes, study suggests

Scientists use brain organoids to identify root causes of Miller-Dieker syndrome

Scientists use brain organoids to identify root causes of Miller-Dieker syndrome

New study shows variation in junk DNA can affect health

New study shows variation in junk DNA can affect health

Kataegis linked to better prognosis for breast cancer patients

Kataegis linked to better prognosis for breast cancer patients

Phase 2 results of AbbVie’s venetoclax in patients with R/R CLL with 17p deletion published in The Lancet Oncology

Phase 2 results of AbbVie’s venetoclax in patients with R/R CLL with 17p deletion published in The Lancet Oncology

PERK inhibition can be a promising therapeutic strategy for neurodegenerative diseases

PERK inhibition can be a promising therapeutic strategy for neurodegenerative diseases

Researchers identify new mutation responsible for spinocerebellar ataxia

Researchers identify new mutation responsible for spinocerebellar ataxia

Specific environmental influences can neutralize effect of genetic variant that increases childhood asthma risk

Specific environmental influences can neutralize effect of genetic variant that increases childhood asthma risk

UK Biobank genetic study shows link between lung disease and smoking behaviour

UK Biobank genetic study shows link between lung disease and smoking behaviour

AbbVie's venetoclax Phase 2 trial meets primary endpoint in patients with relapsed/refractory CLL with 17P deletion

AbbVie's venetoclax Phase 2 trial meets primary endpoint in patients with relapsed/refractory CLL with 17P deletion

IMBRUVICA (ibrutinib) approved in Europe for treatment of Waldenstrom's macroglobulinemia

IMBRUVICA (ibrutinib) approved in Europe for treatment of Waldenstrom's macroglobulinemia

Study on how maternal proteins help regulate initial cell divisions during early development

Study on how maternal proteins help regulate initial cell divisions during early development

Ibrutinib (IMBRUVICA) improves survival in treatment-naïve patients with chronic lymphocytic leukemia

Ibrutinib (IMBRUVICA) improves survival in treatment-naïve patients with chronic lymphocytic leukemia

Pharmacyclics's Phase III RESONATE™ trial shows adherence to 420mg dose of IMBRUVICA improves outcomes in CLL patients

Pharmacyclics's Phase III RESONATE™ trial shows adherence to 420mg dose of IMBRUVICA improves outcomes in CLL patients

Pharmacyclics’ Ibrutinib Phase Ib/II data show ibrutinib may be safe and effective in patients with cGVHD

Pharmacyclics’ Ibrutinib Phase Ib/II data show ibrutinib may be safe and effective in patients with cGVHD

Phase III HELIOS trial results show ibrutinib combination therapy improves outcomes  in CLL/SLL patients

Phase III HELIOS trial results show ibrutinib combination therapy improves outcomes in CLL/SLL patients

Pharmacyclics initiates ibrutinib-MEDI4736 combination multi-center study for R/R DLBCL or FL

Pharmacyclics initiates ibrutinib-MEDI4736 combination multi-center study for R/R DLBCL or FL