Chromosome Y News and Research

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The Y chromosome is one of the two sex chromosomes in humans (the other is the X chromosome). The sex chromosomes form one of the 23 pairs of human chromosomes in each cell. The Y chromosome spans about 58 million base pairs (the building blocks of DNA) and represents almost 2 percent of the total DNA in cells.

Each person normally has one pair of sex chromosomes in each cell. The Y chromosome is present in males, who have one X and one Y chromosome, while females have two X chromosomes.

Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. The Y chromosome likely contains between 70 and 200 genes. Because only males have the Y chromosome, the genes on this chromosome tend to be involved in male sex determination and development. Sex is determined by the SRY gene, which is responsible for the development of a fetus into a male. Other genes on the Y chromosome are important for male fertility.

Many genes are unique to the X or Y chromosome, but genes in an area known as the pseudoautosomal region are present on both chromosomes. As a result, men and women each have two functional copies of these genes. Many genes in the pseudoautosomal region are essential for normal development.

Genes on the Y chromosome are among the estimated 20,000 to 25,000 total genes in the human genome.
Distinguishing biothreat look-alikes could aid biological surveillance

Distinguishing biothreat look-alikes could aid biological surveillance

Scientists develop new system to identify and characterize regulatory DNA sequences

Scientists develop new system to identify and characterize regulatory DNA sequences

New research suggests cell immortalization as more complicated process than originally thought

New research suggests cell immortalization as more complicated process than originally thought

Researchers develop and validate new assay that detects gene fusions in solid tumors

Researchers develop and validate new assay that detects gene fusions in solid tumors

Counteracting premature aging

Counteracting premature aging

Duke researchers map evolution of sex chromosomes in fungus linked to human disease

Duke researchers map evolution of sex chromosomes in fungus linked to human disease

Researchers unravel genetic characteristics that increase risk of developing Tourette syndrome

Researchers unravel genetic characteristics that increase risk of developing Tourette syndrome

Study supports genetic testing as first-line diagnostic method for young children with epilepsy

Study supports genetic testing as first-line diagnostic method for young children with epilepsy

Large clinical study reveals the performance of Natera's Panorama® non-invasive prenatal test

Large clinical study reveals the performance of Natera's Panorama® non-invasive prenatal test

Gene's position on chromosome influences mutations, study shows

Gene's position on chromosome influences mutations, study shows

Princeton scientists test cell-culture system to aid study of HBV infections

Princeton scientists test cell-culture system to aid study of HBV infections

Methicillin use not to blame for MRSA, say researchers

Methicillin use not to blame for MRSA, say researchers

Genetic basis behind friendliness of dogs and humans uncovered in a new study

Genetic basis behind friendliness of dogs and humans uncovered in a new study

Scientists reveal key role of TLK2 gene in placenta development, embryo viability in mice

Scientists reveal key role of TLK2 gene in placenta development, embryo viability in mice

Researchers detect new gene mutation linked to Fanconi anemia

Researchers detect new gene mutation linked to Fanconi anemia

Experts develop first freely available data network for Huntington's disease research

Experts develop first freely available data network for Huntington's disease research

New technique to study genetic changes could enhance cancer diagnosis

New technique to study genetic changes could enhance cancer diagnosis

Study indicates new element involved in genome instability

Study indicates new element involved in genome instability

Existing drugs could help subgroup of patients with osteosarcoma, suggest scientists

Existing drugs could help subgroup of patients with osteosarcoma, suggest scientists

MIT biologists identify how the immune system eliminates genetically imbalanced cells

MIT biologists identify how the immune system eliminates genetically imbalanced cells