Chromosome 15 News and Research

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Humans normally have 46 chromosomes in each cell, divided into 23 pairs. Two copies of chromosome 15, one copy inherited from each parent, form one of the pairs. Chromosome 15 spans about 100 million base pairs (the building blocks of DNA) and represents more than 3 percent of the total DNA in cells.

Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 15 likely contains between 650 and 1,000 genes.

Genes on chromosome 15 are among the estimated 20,000 to 25,000 total genes in the human genome.
Schizophrenia-linked genetic variations and the developing brain: an interview with Prof. Guo-li Ming

Schizophrenia-linked genetic variations and the developing brain: an interview with Prof. Guo-li Ming

Scientists report major breakthrough in understanding molecular basis for Prader-Willi syndrome

Scientists report major breakthrough in understanding molecular basis for Prader-Willi syndrome

Rare abnormality in chromosomes increases risk of rare childhood leukaemia

Rare abnormality in chromosomes increases risk of rare childhood leukaemia

Obsessive-compulsive disorder and Tourette syndrome are highly heritable

Obsessive-compulsive disorder and Tourette syndrome are highly heritable

Prader-Willi syndrome results in dysregulation of circadian and metabolic genes

Prader-Willi syndrome results in dysregulation of circadian and metabolic genes

Research suggests fainting may be genetic while certain triggers may not be inherited

Research suggests fainting may be genetic while certain triggers may not be inherited

Study examines specific form of autism caused by duplication on chromosome 15

Study examines specific form of autism caused by duplication on chromosome 15

CIB2 gene responsible for progression and severity of Usher syndrome

CIB2 gene responsible for progression and severity of Usher syndrome

Study describes how seizures in people with AS could be linked to brain cell activity imbalance

Study describes how seizures in people with AS could be linked to brain cell activity imbalance

Researchers identify genetic marker linked with smoking quantity in African Americans

Researchers identify genetic marker linked with smoking quantity in African Americans

New way to awaken paternal Ube3a allele linked with Angelman syndrome

New way to awaken paternal Ube3a allele linked with Angelman syndrome

Common genetic variant may predispose people to acute dissections

Common genetic variant may predispose people to acute dissections

Genetic mutation linked to Kufs disease

Genetic mutation linked to Kufs disease

Scientists use new technologies to identify genetic cause of Kufs disease

Scientists use new technologies to identify genetic cause of Kufs disease

Sequencing the genomes of cancer patients help doctors decide the best course of treatment

Sequencing the genomes of cancer patients help doctors decide the best course of treatment

Genetic variant contributes to higher risk of lung cancer, increases tendency to smoke more

Genetic variant contributes to higher risk of lung cancer, increases tendency to smoke more

Study finds common risk factors linked with painkiller addiction

Study finds common risk factors linked with painkiller addiction

Researchers identify gene associated with susceptibility to chronic pain caused by nerve injury

Researchers identify gene associated with susceptibility to chronic pain caused by nerve injury

Gene associated with susceptibility to chronic pain caused by nerve injury identified

Gene associated with susceptibility to chronic pain caused by nerve injury identified

Three genetic regions associated with cigarette smoking

Three genetic regions associated with cigarette smoking