Chromosome 22 News and Research

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Humans normally have 46 chromosomes (23 pairs) in each cell. Two copies of chromosome 22, one copy inherited from each parent, form one of the pairs. Chromosome 22 is the second smallest human chromosome, spanning about 50 million DNA building blocks (base pairs) and representing between 1.5 percent and 2 percent of the total DNA in cells.

In 1999, researchers working on the Human Genome Project announced they had determined the sequence of base pairs that make up this chromosome. Chromosome 22 was the first human chromosome to be fully sequenced.

Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 22 likely contains between 500 and 800 genes.

Genes on chromosome 22 are among the estimated 20,000 to 25,000 total genes in the human genome.
Scientists gain new insight into DiGeorge syndrome

Scientists gain new insight into DiGeorge syndrome

Chromosome losses can signal an especially poor response to therapy

Chromosome losses can signal an especially poor response to therapy

Study sheds new light on children with a severe form of acute lymphoblastic leukemia

Study sheds new light on children with a severe form of acute lymphoblastic leukemia