Chromosome 8 News and Research

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Humans normally have 46 chromosomes in each cell, divided into 23 pairs. Two copies of chromosome 8, one copy inherited from each parent, form one of the pairs. Chromosome 8 spans about 146 million DNA building blocks (base pairs) and represents between 4.5 percent and 5 percent of the total DNA in cells.

Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 8 likely contains between 700 and 1,100 genes.

Genes on chromosome 8 are among the estimated 20,000 to 25,000 total genes in the human genome.
Researchers discover how chromosomal instability allows cancer cells to avoid immune defenses

Researchers discover how chromosomal instability allows cancer cells to avoid immune defenses

Study reveals how ecDNA fragments drive gene amplification to generate drug resistance in cancer

Study reveals how ecDNA fragments drive gene amplification to generate drug resistance in cancer

Researchers discover how shattered chromosomes make cancer cells more aggressive

Researchers discover how shattered chromosomes make cancer cells more aggressive

COVID-19 severity could be linked to genetic variance

COVID-19 severity could be linked to genetic variance

Scientists discover molecular defects associated with rare genetic disorder in children

Scientists discover molecular defects associated with rare genetic disorder in children

New understanding of physical properties of chromatin may show how genome is encoded and decoded

New understanding of physical properties of chromatin may show how genome is encoded and decoded

Study highlights how the sex differences in COVID-19 are linked to ACE2 protein

Study highlights how the sex differences in COVID-19 are linked to ACE2 protein

BU researchers awarded $2.4 million NIH grant to study idiopathic pulmonary fibrosis

BU researchers awarded $2.4 million NIH grant to study idiopathic pulmonary fibrosis

Autoimmune condition biomarkers promote SARS-CoV-2 viral entry, study finds

Autoimmune condition biomarkers promote SARS-CoV-2 viral entry, study finds

Neanderthal gene variant increases risk of severe COVID-19

Neanderthal gene variant increases risk of severe COVID-19

Study explores link between aging, obesity, and metabolic diseases

Study explores link between aging, obesity, and metabolic diseases

Study unlocks some muscle cell secrets

Study unlocks some muscle cell secrets

UCLA researchers identify gene that could help predict cervical cancer treatment response

UCLA researchers identify gene that could help predict cervical cancer treatment response

IGC researchers receive three out of six European Research Council grants

IGC researchers receive three out of six European Research Council grants

High error rates found in human egg cells

High error rates found in human egg cells

Chemotherapy combined with blinatumomab increases survival for patients with Ph-negative B-ALL

Chemotherapy combined with blinatumomab increases survival for patients with Ph-negative B-ALL

Genetic variants in pediatric cancer survivors of African ancestry increase risk of heart problems

Genetic variants in pediatric cancer survivors of African ancestry increase risk of heart problems

Study identifies multiple important genomic differences in BCL malignancies using genomic ancestry

Study identifies multiple important genomic differences in BCL malignancies using genomic ancestry

Researchers develop a promising fix to CRISPR-Cas9's unwanted changes problem

Researchers develop a promising fix to CRISPR-Cas9's unwanted changes problem

Study outlines a new role for pregnancy-associated plasma protein A in gestational diabetes

Study outlines a new role for pregnancy-associated plasma protein A in gestational diabetes