Chronic Obstructive Lung Disease News and Research

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Researchers successfully create infinitely reproducing tissue cultures

Most cases of small cell lung cancer are only diagnosed after the tumour has already formed metastases. Until now it has not been possible to investigate the reasons for this rapid metastasis, because of a lack of sufficient tumour material from patients. Now, the group of researchers led by Gerhard Hamilton, University Department of Surgery at Medical University of Vienna has succeeded in creating infinitely reproducing tissue cultures.

22 Nov 2015

Experts to gather at DOHaD congress to address challenges that impact health of children, adolescents

Over 600 experts from around the world will meet to address the many challenges that currently impact the health of mothers, babies in the womb, infants, children and adolescents at the Society for the Developmental Origins of Health and Disease congress, which will be held in Africa for the first time.

5 Nov 2015

Novartis announces FDA approval of dual combination bronchodilator Utibron Neohaler for COPD patients

Novartis announced today that the US Food and Drug Administration has approved the dual combination bronchodilator Utibron Neohaler (indacaterol/glycopyrrolate) inhalation powder for the long-term maintenance treatment of airflow obstruction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema. It is not indicated to treat asthma or sudden symptoms of COPD.

30 Oct 2015

New OTEMTO phase three results show potential improvement to quality of life for COPD patients

Boehringer Ingelheim announced the publication of new data from the Phase IIIb OTEMTO® 1&2 trials (NCT01964352/NCT02006732), which show Spiolto® Respimat® (tiotropium/olodaterol) provides consistent, clinically meaningful improvements in quality of life versus placebo in patients with COPD

17 Aug 2015

FEV1/FVC lower limit of normal aids surgery risk stratification in COPD

Researchers say that using the lower limit of normal of the forced expiration volume in 1 second/forced vital capacity ratio improves risk stratification in patients with chronic obstructive pulmonary disease undergoing thoracic surgery.

27 May 2015

GOLD 2007 and 2011 fail to accurately predict mortality risk

Neither the 2007 nor the 2011 Global Initiative for Chronic Obstructive Lung Disease classification systems have sufficient prognostic accuracy to predict mortality, a pooled analysis of individual patient data shows.

27 May 2015

Gene variations predispose mestizo Mexican population to develop severe form of COPD

A study by Ramcés Falfán-Valencia, researcher at the National Institute of Respiratory Diseases, found that the mestizo Mexican population has a number of variations in certain genes that predispose them to develop the most severe form of chronic obstructive pulmonary disease (COPD).

19 Dec 2014

COPD overlooked in cardiovascular patients

More than a quarter of patients with cardiovascular disease and a history of smoking also have air flow limitation compatible with chronic obstructive pulmonary disease, Japanese study data show.

13 Aug 2014

Elevated blood eosinophil levels find to be risk factor for exacerbations in asthma patients

In adults with persistent asthma, elevated blood eosinophil levels may be able to predict which individuals are at increased risk for exacerbations, according to a new study presented at the 2014 American Thoracic Society International Conference.

21 May 2014

FDA OOPD grants orphan drug designation to Alitair's Erdosteine for treatment of bronchiectasis

Alitair Pharmaceuticals, Inc., today announced that the Office of Orphan Products Development of the Food and Drug Administration has granted orphan drug designation for its drug candidate, Erdosteine, for the treatment of bronchiectasis. Erdosteine is a mucolytic with antibacterial, anti-inflammatory, and antioxidant properties.

7 Jan 2014

BAL findings boost non-smoking COPD distinction

Research shows that smoking status, and not airway obstruction, determines the distribution of T cell subsets in bronchoalveolar lavage in patients with chronic obstructive pulmonary disease.

2 Dec 2013

New biomarkers to improve diagnostics of prostate cancer

New biomarkers will improve diagnostics of endemic diseases in future, such as prostate cancer. Their mission: to recognize the tumor earlier and classify it more precisely - thereby helping avoid unnecessary operations.

2 Dec 2013

Chronic bronchitis could indicate COPD subtype

Chronic bronchitis is common among patients with chronic obstructive disease and may represent a subtype of the disease that places patients at risk for increased severity and exacerbations, say researchers.

22 Nov 2013

ICS overuse warning in COPD

Researchers from the UK caution that inhaled corticosteroids are being overused in patients with chronic obstructive pulmonary disease, in light of a lack of solid evidence for their efficacy, limited guideline support, and growing concerns over their association with pneumonia.

11 Nov 2013

Active management boosts patient satisfaction with COPD care

A disease management program for chronic obstructive pulmonary disease based on the Chronic Care Model leads to greater patient satisfaction with care than standard disease management, a randomized trial suggests.

30 Oct 2013

Twitch mouth pressure reflects COPD disease severity

Researchers from China have shown that a non-invasive method of measuring inspiratory muscle strength accurately reflects the severity of chronic obstructive pulmonary disease.

21 Oct 2013

COPD investigational treatments: an interview with Dr. Tunde Otulana, Senior Vice President, Clinical Development and Medical Affairs, Boehringer Ingelheim Pharmaceuticals, Inc.

Olodaterol is a long-acting beta2-agonist (LABA) bronchodilator delivered via the Respimat® inhaler. It is being investigated as a once daily maintenance bronchodilator treatment of airflow obstruction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.

21 Oct 2013