Cilia News and Research

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Unlocking the secrets of Omicron: study reveals how unique spike mutations enable enhanced infectivity and resistance to immune barrier

Researchers reported the increased transmissibility of the severe acute respiratory syndrome coronavirus 2.

11 May 2023

Discovery could pave the way for new approaches to treating chronic respiratory diseases

An international research team has discovered a new cell state in embryonic airway development that has been overlooked until now.

11 Apr 2023

FDA-approved drug keeps light-sensitive photoreceptors alive in lab models of LCA 10

A National Institutes of Health team has identified a compound already approved by the U.S. Food and Drug Administration that keeps light-sensitive photoreceptors alive in three models of Leber congenital amaurosis type 10 (LCA 10), an inherited retinal ciliopathy disease that often results in severe visual impairment or blindness in early childhood.

29 Mar 2023

Researchers to investigate how viral proteins contribute to influenza spread

Influenza viruses have an enormous impact in the U.S., with an estimated 25 million illnesses and 18,000 deaths in the 2022-23 flu season alone.

20 Mar 2023

How does temperature affect host responses to SARS-CoV-2 and IAV infection in human nasal epithelial cells?

A new preprint examines the response to these pathogens in the nose, which is the primary portal of entry for both.

13 Mar 2023

Influenza A virus suppresses SARS-CoV-2 replication during co-infection

SARS-CoV-2 does not suppress the replication of influenza A in simultaneous or sequential co-infections.

13 Feb 2023

Mucoactive drugs block SARS-CoV-2 infection

Researchers evaluate the effects of mucociliary active molecules on SARS-CoV-2 infection in vitro.

7 Feb 2023

Study shows SARS-CoV-2 exhibits differential tropism for nasal epithelial cells with age

Researchers explored the relationship between the development of goblet inflammatory cells and the age-related pathophysiology of SARS-CoV-2.

19 Jan 2023

Immotile cilia sense the direction of extracellular fluid during development to break left-right symmetry

Tiny, immobile cilia sense the direction of extracellular fluid during development to break left-right symmetry during early embryogenesis, researchers report in two independent studies that investigate this mechanism in mice embryos and zebrafish, respectively.

5 Jan 2023

Scientists pinpoint the routes taken by SARS-CoV-2 to enter and exit cells in our nasal cavity

Somebody just coughed on you. On a plane. At a dinner party. In a supermarket line. If only there were a "morning after" nasal spray that could knock out respiratory viruses' ability to colonize your nose and throat.

5 Jan 2023

Cilia act as sensors to establish body left-right asymmetry during embryogenesis

Although the human body is externally symmetric across the left-right axis, there are remarkable left-right asymmetries in the shape and positioning of most internal organs including the heart, lungs, liver, stomach, and brain.

5 Jan 2023

Researchers discover new cellular component with importance for the sense of smell

Researchers at Umeå University have discovered a previously unknown cellular component, an organelle, inside neurons that we use to perceive smell.

4 Jan 2023

Innovations in expansion microscopy allow unprecedented view of the interior of cells

Unprecedented views of the interior of cells and other nanoscale structures are now possible thanks to innovations in expansion microscopy.

2 Jan 2023

Virus-only diet can fuel the physiological and population growth of an organism

Over a single day, in the placid waters of a single pond, a million virus particles might enter a single-celled organism known for the minuscule hairs, or cilia, that propel it through those waters.

27 Dec 2022

Removal of cilia from the brain's striatum impairs time perception and judgment, study finds

Researchers at the University of California, Irvine have discovered that removal of cilia from the brain's striatum region impaired time perception and judgment, revealing possible new therapeutic targets for mental and neurological conditions including schizophrenia, Parkinson's and Huntington's diseases, autism spectrum disorder, and Tourette syndrome.

30 Nov 2022

Researchers reveal native 3D structure of the ciliary base for the first time

Cilia are small hair-like organelles that extend from cells and perform many functions, including motility and signaling.

19 Sep 2022

New gene therapy approach could help prevent blindness in children with Leber congenital amaurosis

Researchers from the National Eye Institute have developed a gene therapy that rescues cilia defects in retinal cells affected by a type of Leber congenital amaurosis (LCA), a disease that causes blindness in early childhood.

8 Sep 2022

New kind of synapse discovered in neurons’ tiny hairs

Scientists at HHMI's Janelia Research Campus have discovered a new kind of synapse in the tiny hairs on the surface of neurons.

1 Sep 2022

Discovery paves the way for specific therapies for common form of childhood brain and spine tumor

A study conducted by researchers in Brazil, Australia, Austria and the United States has made significant discoveries about a type of pediatric cancer with no approved drugs for treatment and with a low survival rate.

29 Aug 2022

Neuronal cilia are important for dopamine receptor 1 signaling, study shows

A historically overlooked rod-like projection present on nearly every cell type in the human body may finally be getting its scientific due: A new study has found that these appendages, called cilia, on neurons in the brain have a key role in ensuring a specific dopamine receptor's signals are properly received.

9 Aug 2022

Cilia News and Research

Unlocking the secrets of Omicron: study reveals how unique spike mutations enable enhanced infectivity and resistance to immune barrier

Discovery could pave the way for new approaches to treating chronic respiratory diseases

FDA-approved drug keeps light-sensitive photoreceptors alive in lab models of LCA 10

Researchers to investigate how viral proteins contribute to influenza spread

How does temperature affect host responses to SARS-CoV-2 and IAV infection in human nasal epithelial cells?

Influenza A virus suppresses SARS-CoV-2 replication during co-infection

Mucoactive drugs block SARS-CoV-2 infection

Study shows SARS-CoV-2 exhibits differential tropism for nasal epithelial cells with age

Immotile cilia sense the direction of extracellular fluid during development to break left-right symmetry

Scientists pinpoint the routes taken by SARS-CoV-2 to enter and exit cells in our nasal cavity

Cilia act as sensors to establish body left-right asymmetry during embryogenesis

Researchers discover new cellular component with importance for the sense of smell

Innovations in expansion microscopy allow unprecedented view of the interior of cells

Virus-only diet can fuel the physiological and population growth of an organism

Removal of cilia from the brain's striatum impairs time perception and judgment, study finds

Researchers reveal native 3D structure of the ciliary base for the first time

New gene therapy approach could help prevent blindness in children with Leber congenital amaurosis

New kind of synapse discovered in neurons’ tiny hairs

Discovery paves the way for specific therapies for common form of childhood brain and spine tumor

Neuronal cilia are important for dopamine receptor 1 signaling, study shows

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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