Cleft Palate News and Research

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Cleft lip and cleft palate are birth defects that affect the upper lip and roof of the mouth. They happen when the tissue that forms the roof of the mouth and upper lip don't join before birth. The problem can range from a small notch in the lip to a groove that runs into the roof of the mouth and nose. This can affect the way the child's face looks. It can also lead to problems with eating, talking and ear infections.

Study provides insight into genetic causes of cleft lip and cleft palate

Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, have identified how a specific stretch of DNA controls far-off genes to influence the formation of the face.

28 May 2014

Patients with cleft palate can benefit from bone lengthening technique

A technique called distraction osteogenesis can create increased length of the upper jaw in patients with cleft lip and palate deformities, reports a study in the March issue of The Journal of Craniofacial Surgery, edited by Mutaz B. Habal, MD, published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

17 Mar 2014

Natera initiates distribution partnership with ProPath for Panorama non-invasive prenatal screening test

Natera, a leading innovator in prenatal genetic testing, today announced the initiation of a distribution partnership with ProPath, a wholly physician-owned provider of pathology services to clinicians and medical facilities in the United States, for its Panorama non-invasive prenatal screening test (NIPT).

From Natera 12 Feb 2014

Pregnant women exposed to metoclopramide experience no increased risk of congenital malformations

In an analysis that included more than 40,000 women exposed to the nausea medication metoclopramide in pregnancy, use of this drug was not associated with significantly increased risk of major congenital malformations overall, spontaneous abortion, and stillbirth, according to a study in the October 16 issue of JAMA.

16 Oct 2013

Risk for childhood cancer moderately increased among adolescents with major birth defects

A multistate study led by researchers at the University of Utah has revealed that the risk for childhood cancer is moderately increased among children and young adolescents with certain types of major birth defects.

12 Aug 2013

International Consortium receives grant to examine genetic reasons of schizophrenia in deletion syndrome patients

Today, the Royal College of Surgeons in Ireland (RCSI) will host a two day International Brain and Behaviour Consortium meeting on Chromosome 22q11.2 Deletion Syndrome (22q11.2DS).

24 Jul 2013

Covered California selects Delta Dental to offer affordable dental coverage to children

Delta Dental of California announced today its selection by Covered California as one of six companies that will make affordable dental coverage available to California children up to 19 years old in the state's health exchange.

27 Jun 2013

CSHL scientists solve the mystery of why some infants born with grave syndrome

By identifying a protein that acts as a genetic modifier, scientists at Cold Spring Harbor Laboratory have solved the mystery of why some infants are born with a grave syndrome consisting of cleft palate and major deformities of the skin and limbs, while other infants bearing the same predisposing genetic mutation bear little or no sign of the illness, called EEC.

14 Jun 2013

Craniofacial surgeons recommend steps to reduce risk of pneumonitis from povidone-iodine

A routine step in preparing for cleft palate surgery in a child led to an unusual-but not unprecedented-case of lung inflammation (pneumonitis), according to a report in the The Journal of Craniofacial Surgery. The journal, edited by Mutaz B. Habal, MD, FRCSC, is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

22 Feb 2013

Cleft palate children need regular hearing check-ups

Children with cleft palate require regular audiologic and otologic follow-up to ensure their management is appropriate and timely, say researchers.

12 Dec 2012

Nontraditional velopharyngoplasty predictor unveiled

The necessity of subsequent velopharyngoplasty does not depend on the time of soft palate closure and type of cleft, say researchers.

28 Nov 2012

Vitamin D may help prevent dental caries

A new review of existing studies points toward a potential role for vitamin D in helping to prevent dental caries, or tooth decay.

28 Nov 2012

Four transcription factor genes control processes related to heart and head muscle formation

A group of researchers in Israel, the United States and other nations have made important advances in the rapidly-expanding field of "regenerative medicine," outlining for the first time connections in genetic regulation that normally prevent birth defects in heart and facial muscles.

30 Oct 2012

Study examines environmental and biological impacts on children with cleft lip and palate

Children with cleft lip and/or palate encounter different challenges throughout the course of their development. Both environmental and biological factors play a role, and can affect speech, academic performance, and behavior. Research has shown varying influences, including the type of cleft, gender, and age, affecting outcomes.

16 Aug 2012

New health professional roles emerge within the marketplace

This pair of stories from Kaiser Health News reports on new kinds of health professionals and the role they have within the health care continuum.

23 Jul 2012

First Edition: July 23, 2012

In this Kaiser Health News video, Greg Millett, a senior policy advisor in the Office of National AIDS Policy, tells Joanne Silberner that the president's National HIV/AIDS Strategy has improved coordination among federal agencies and that the 2010 health law will improve access to care for those living with HIV/AIDS.

23 Jul 2012

Vivus receives FDA approval for Qsymia to manage chronic weight

The U.S. Food and Drug Administration today approved Qsymia (phentermine and topiramate extended-release) as an addition to a reduced-calorie diet and exercise for chronic weight management.

18 Jul 2012

More reason to take folic acid while pregnant

Taking folic acid supplements during pregnancy can significantly reduce the likelihood for babies being born with cleft lip and palate, researchers say.

2 Jul 2012

NIH awards $1.9M grant to study genetic control of cell migration

Developmental biologists Dominique Alfandari and Hélène Cousin at the University of Massachusetts Amherst recently received a five-year, $1.9 million grant from the U.S. National Institutes of Health to investigate craniofacial development in a frog model to better understand genetic control of cell migration.

2 Jun 2012

Children with craniofacial disorders face numerous medical challenges beyond appearance

Children born with cleft lip, cleft palate and other craniofacial disorders face numerous medical challenges beyond appearance.

23 May 2012