Clinical Depression News and Research

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AssureRx closes $11 million Series B financing

AssureRx Health, Inc. today announced the closing of an $11 million Series B financing. The personalized medicine company, which provides clinically-relevant information to help physicians select the right drug and the right dose for individual neuropsychiatric patients, will use the funds to expand direct sales and marketing for its first product, GeneSightRx®, and for second generation product development activities.

25 Mar 2011

Brain's pleasure and reward circuitry gets a big boost after a sleepless night

A sleepless night can make us cranky and moody. But a lesser known side effect of sleep deprivation is short-term euphoria, which can potentially lead to poor judgment and addictive behavior, according to new research from the University of California, Berkeley.

24 Mar 2011

Clinical depression can exacerbate Knee osteoarthritis symptoms in elder patients

Clinical depression can exacerbate the symptoms of knee arthritis beyond what is evident on X-rays, according to a new study from the Journal of Bone and Joint Surgery.

17 Mar 2011

Neuralstem announces initiation of NSI-189 Phase Ia trial for major depressive disorder

Neuralstem, Inc. announced that the first subject was dosed yesterday in a Phase Ia trial to evaluate the safety of its drug, NSI-189, which is being developed for the treatment of major depressive disorder and other psychiatric indications. NSI-189 is the lead compound in Neuralstem's neurogenerative small molecule drug platform. This phase of the trial is in healthy volunteers and seeks to determine the maximum tolerated single dose.

2 Mar 2011

Research: Blood and hormone level in saliva can reveal burnout symptoms

Your blood and the level of a hormone in your spit could reveal if you're on the point of burnout, according to research undertaken by Dr. Sonia Lupien and Robert-Paul Juster of the Centre for Studies on Human Stress of Louis-H. Lafontaine Hospital and the University of Montreal.

22 Feb 2011

Non-specialist mental health staff can treat depression with psychotherapy

Depression can be treated effectively with psychotherapy by mental health nurses with minimal training, according to new preliminary research findings.

16 Feb 2011

Patients and spouses experience distress related to diabetes

Older patients with diabetes who are not dealing well with the disease are likely to have symptoms of depression, and spouses of older patients also suffer distress related to diabetes and its management, according to research from Purdue University.

28 Jan 2011

Composer Fr-d-ric Chopin probably had temporal lobe epilepsy

The composer Fr-d-ric Chopin, who regularly hallucinated, probably had temporal lobe epilepsy throughout his short life, reveals research published online in Medical Humanities. Hallucinations typically feature in seizure disorders, they say.

25 Jan 2011

Winter depression is more common in women than men

As the winter months approach bringing holidays and good cheer, certain health issues may arise that women should have on their radar. From mental health issues like stress, depression and seasonal affective disorder (SAD), to physical concerns like skin care, the winter can certainly pack a punch.

6 Jan 2011

Maternal depression adversely affects quality of life in children with epilepsy

A study by Canadian researchers examined the prevalence of maternal depression and its impact on children newly diagnosed with epilepsy. Prevalence of depression in mothers ranged from 30%-38% within the first 24 months following a child’s epilepsy diagnosis. The mother’s depressive symptoms negatively impacted the child’s health-related quality of life, but the effects were moderated by the amount of family resources and mediated by how well the family functions and the extent of family demands. Details of this novel study appear online in Epilepsia, a journal published by Wiley-Blackwell on behalf of the International League Against Epilepsy.

5 Jan 2011

Child's epilepsy diagnosis impacts mother's mental health and family environment

5 Jan 2011

Study finds association between personality, cognitive ability and neuroendocrinal dysfunction in exhaustion syndrome

Exhaustion syndrome, also called burnout and exhaustion depression, leaves objectively measurable changes in the brain including reduced activity in the frontal lobes and altered regulation of the stress hormone cortisol. This is shown in a new dissertation from Umeå University in Sweden.

18 Nov 2010

Health Net partners with DoD for Major Depression Disease Management Program

Health Net Federal Services, LLC, part of the Government Contracts segment of Health Net, Inc. (NYSE:HNT), today announced its Major Depression Disease Management Program established in partnership with the Department of Defense (DoD) for TRICARE beneficiaries, ages 18-64. TRICARE is the DoD's health care plan for active duty and retired service members and their families.

18 Nov 2010

Bereaved patients have increased heart rate and reduced heart rate variability: Study

The death of a spouse or child can cause elevated heart rate and other potentially harmful heart rhythm changes among the recently bereaved, according to research presented at the American Heart Association's Scientific Sessions 2010.

15 Nov 2010

Depressed pregnant women at increased risk of delivering preterm birth and low-birth weight infants

Clinical depression puts pregnant women at increased risk of delivering prematurely and of giving birth to below-normal weight infants, according to a report published Oct. 4 in the Archives of General Psychiatry.

5 Oct 2010

Depression treatment guidelines updated

There has been an update in the treatment of clinical depression. This includes suggestions on the use of medication, talk therapy, exercise, and alternative treatments and puts more emphasis on tailor made treatments for patients.

4 Oct 2010

VIVUS announces QNEXA study results for obesity treatment

VIVUS, Inc. today announced positive top-line results from a two-year study of QNEXA(phentermine/topiramate) Controlled Release Capsules, an investigational therapy for treatment of obesity, a condition that affects approximately one-third of adult Americans.

21 Sep 2010

Heart patients with Type D personality at higher risk of future cardiovascular problems

Heart patients with the "distressed" (Type D) personality profile may face a higher risk of future cardiovascular problems, according to a summary article published in the American Heart Association journal Circulation: Cardiovascular Quality and Outcomes.

15 Sep 2010

SAMe dietary supplement effective for major depressive disorders: Study

A new study conducted by investigators at Harvard Medical School and Massachusetts General Hospital (MGH) suggests that S-Adenosyl Methionine (SAMe), an over-the-counter dietary supplement, can be an effective, relatively well-tolerated, adjunctive treatment for adults with major depressive disorders who do not respond to their treatment with antidepressant medication.

2 Sep 2010

Mental health issues during pregnancy contribute to infant mortality and poor child health

Clinical depression and anxiety during pregnancy results in smaller babies that are more likely to die in infancy, according to new research published in the open access journal BMC Public Health. The study, which focused on women living in rural Bangladesh, provides the first finding of its kind in a non-Western population. The research indicates that mental health issues are likely to be a primary contributor to infant mortality and poor child health, above poverty, malnutrition or low socio-economic status.

26 Aug 2010