Clinical Trial News and Research

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New trials show promise for immune checkpoint blockers in early-stage lung cancer

A dendritic cell (DC) vaccine targeting patient-specific neoantigens to patients with resected non-small cell lung cancer (NSCLC).

18 Apr 2024

Breakthrough imaging method enhances precision in prostate cancer treatment

A novel SPECT/CT acquisition method can accurately detect radiopharmaceutical biodistribution in a convenient manner for prostate cancer patients, opening the door for more personalized treatment.

17 Apr 2024

Penn State study examines how a person's telomeres are affected by caloric restriction

Penn State researchers may have uncovered another layer of complexity in the mystery of how diet impacts aging.

17 Apr 2024

Phase 3 trial shows overall survival benefit from adjuvant therapy in kidney cancer patients

For the first time in fifty years, results from a phase 3 randomized, placebo-controlled trial have shown an overall survival benefit from an adjuvant therapy in patients with kidney cancer.

17 Apr 2024

Online video therapy comparable to in-person visits after thumb CMC arthroplasty

For patients undergoing carpometacarpal (CMC) joint surgery for treatment of thumb osteoarthritis, the use of online video instruction for postoperative hand therapy is associated with outcomes similar to in-person therapy visits – while substantially reducing travel time and distance, reports a clinical trial in The Journal of Bone & Joint Surgery.

17 Apr 2024

Universities collaborate on $15 million project investigating inflammation's role in cardiac and brain diseases

Research teams from Northwestern University Chicago Campus, University of Michigan and University of Pittsburgh will lead a $15 million project dedicated to studying inflammation's role in cardiac and brain diseases.

17 Apr 2024

Combined chemohormonal therapy for locally advanced prostate cancer offers extended control of PSA levels

For patients with locally advanced prostate cancer, combined treatment with chemotherapy and hormonal therapy offers extended control of prostate-specific antigen (PSA) levels, compared to hormonal therapy alone, reports a study in the April issue of The Journal of Urology, an Official Journal of the American Urological Association.

17 Apr 2024

Renaissance of "food as medicine" in modern clinical trials

Priya Venkatesan discusses in Nature Medicine how dietary interventions can prevent or delay diseases, highlighting the reemergence of "food as medicine" in modern clinical trials.

17 Apr 2024

New research shows the feasibility of improving early detection and prevention of pancreatic cancer

New research in the April 2024 issue of JNCCN-;Journal of the National Comprehensive Cancer Network showcases the feasibility of improving early detection and prevention for pancreatic cancer.

16 Apr 2024

FDA announces recall of heart pumps linked to deaths and injuries

A pair of heart devices linked to hundreds of injuries and at least 14 deaths has received the FDA's most serious recall, the agency announced Monday.

16 Apr 2024

Common HIV drugs linked to reduced Alzheimer's disease risk

Alzheimer's disease (AD) currently afflicts nearly seven million people in the U.S. With this number expected to grow to nearly 13 million by 2050, the lack of meaningful therapies represents a major unmet medical need.

16 Apr 2024

Pitt researchers uncover mechanisms behind uveal melanoma resistance

New research from the University of Pittsburgh explains why metastatic uveal melanoma is resistant to conventional immunotherapies and how adoptive therapy, which involves growing a patient's T cells outside the body before reinfusing them, can successfully treat this rare and aggressive cancer.

16 Apr 2024

The Lancet Breast Cancer Commission: Tackling inequalities, hidden costs, and empowering patients

Breast cancer is now the world's most common cancer; at the end of 2020, 7.8 million women were alive having been diagnosed in the previous five years.

16 Apr 2024

Epilepsy drug prevents brain tumor formation and growth in mouse models of NF1

A drug used to treat children with epilepsy prevents brain tumor formation and growth in two mouse models of neurofibromatosis type 1 (NF1), according to a study by researchers at Washington University School of Medicine in St. Louis.

15 Apr 2024

Antibiotics ineffective for cough treatment in lower respiratory tract infections

Use of antibiotics provided no measurable impact on the severity or duration of coughs even if a bacterial infection was present, finds a large, prospective study of people who sought treatment in U.S. primary or urgent care settings for lower-respiratory tract infections.

15 Apr 2024

Breakthrough brain stimulator could revolutionize treatment for neurological disorders

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Clinical Trial News and Research

New trials show promise for immune checkpoint blockers in early-stage lung cancer

Breakthrough imaging method enhances precision in prostate cancer treatment

Penn State study examines how a person's telomeres are affected by caloric restriction

Phase 3 trial shows overall survival benefit from adjuvant therapy in kidney cancer patients

Online video therapy comparable to in-person visits after thumb CMC arthroplasty

Universities collaborate on $15 million project investigating inflammation's role in cardiac and brain diseases

Combined chemohormonal therapy for locally advanced prostate cancer offers extended control of PSA levels

Renaissance of "food as medicine" in modern clinical trials

New research shows the feasibility of improving early detection and prevention of pancreatic cancer

FDA announces recall of heart pumps linked to deaths and injuries

Common HIV drugs linked to reduced Alzheimer's disease risk

Pitt researchers uncover mechanisms behind uveal melanoma resistance

The Lancet Breast Cancer Commission: Tackling inequalities, hidden costs, and empowering patients

Epilepsy drug prevents brain tumor formation and growth in mouse models of NF1

Antibiotics ineffective for cough treatment in lower respiratory tract infections

Breakthrough brain stimulator could revolutionize treatment for neurological disorders

Can psychedelics improve sexual functioning and satisfaction?

Esketamine after childbirth cuts risk of postnatal depression by three-quarters

Understanding the role of genetic variants in male infertility

Study shows exercise can reverse age-related lipid accumulation

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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