Clinical Trial News and Research

RSS

Infant feeding and the development of obesity: what does the science tell us?

On Wednesday, April 9, 2008, a symposium at the American Society for Nutrition's annual meeting at Experimental Biology was held in which noted scientists discussed new infant feeding studies that used methodology such as randomized clinical trials (involving breastfeeding promotion) as well as sibling pairs analysis.

11 Apr 2008

Hospitalization linked to increased mortality in heart failure patients

Patients with heart failure are at increased risk of death if they are hospitalized for worsening heart failure symptoms, according to new research from UAB (University of Alabama at Birmingham).

11 Apr 2008

New devices and research for mechanical circulatory support in pediatrics

New devices and research for mechanical circulatory support in pediatrics from the National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) Pediatric Circulatory Support Program will be discussed at the International Society for Heart and Lung Transplantation (ISHLT) 28th Annual Meeting and Scientific Sessions.

10 Apr 2008

Lower target levels for blood pressure, LDL-cholesterol may provide cardiovascular benefits

Patients with diabetes who reduced their blood pressure and LDL-cholesterol to below standard target levels had a greater decrease in carotid artery wall thickness, but did not have a significant difference in cardiovascular disease events than patients who had recommended blood pressure and LDL-cholesterol levels, according to a study in the April 9 issue of JAMA, the Journal of the American Medical Association.

9 Apr 2008

Tart cherries cut heart/diabetes risk factors

Tart cherries - frequently sold dried, frozen or in juice - may have more than just good taste and bright red color going for them, according to new animal research from the University of Michigan Cardiovascular Center.

7 Apr 2008

Special journal section explores geriatric assessment

The latest issue of The Journal of Gerontology: Medical Sciences (Vol. 63, No. 3) features a special section devoted to the phenomenon of multidimensional geriatric assessment - an interdisciplinary diagnostic process to determine the medical, psychological, and functional status of at-risk and frail elderly patients in order to develop a coordinated, integrated plan for treatment and long-term follow-up.

7 Apr 2008

Roswell Park Cancer Institute awarded three-years funding for ovarian cancer vaccine

The Ovarian Cancer Research Fund has awarded a $900,000 research grant to Kunle Odunsi, MD, Department of Gynecologic Oncology, and his colleagues at Roswell Park Cancer Institute (RPCI) to collaborate on developing a promising vaccine to unleash the power of the immune system against cancer.

7 Apr 2008

FDA approves TREANDA (bendamustine hydrochloride) for chronic lymphocytic leukemia

Cephalon, Inc. has announced that the U.S. Food and Drug Administration (FDA) has approved TREANDA (bendamustine hydrochloride) for Injection for the treatment of patients with chronic lymphocytic leukemia (CLL), a slowly progressing blood and bone marrow disease, on March 20, 2008.

7 Apr 2008

Clinical trial to test a novel HIV/AIDS vaccine

This new vaccine aims to overcome the problem of preexisting immunity to common vaccine vectors, which is thought to be a major problem in the developing world.

4 Apr 2008

New nano-engineered gel inhibits for spinal cord injury

A spinal cord injury often leads to permanent paralysis and loss of sensation below the site of the injury because the damaged nerve fibers can't regenerate.

3 Apr 2008

Rimonabant shows mixed results for slowing progression of coronary disease

The anti-obesity medication rimonabant showed mixed results in slowing progression of coronary artery disease in patients with abdominal obesity and pre-existing coronary disease, according to a new study in the April 2 issue of JAMA.

2 Apr 2008

Chemotherapy-induced anemia increases risk of local breast cancer recurrence

Patients with breast cancer who developed anemia during chemotherapy had nearly three times the risk of local recurrence as those who did not, according to a study published in the April 1 issue of Clinical Cancer Research¸ a journal of the American Association for Cancer Research.

2 Apr 2008

New type of imaging system illuminates tumors to nearly one-trillionth of a meter

Doctors' quest to see what is happening inside a living body has been hampered by the limits on detecting tiny components of internal structures and events.

1 Apr 2008

Eli Lilly starts trial of treatment of mild to moderate Alzheimer's disease

Eli Lilly and Company has announced the start of a Phase III clinical trial studying LY450139, an investigational gamma secretase inhibitor for the treatment of mild to moderate Alzheimer's disease.

1 Apr 2008

Disappointing resuts for pimecrolimus, investigational anti-restenosis drug

A new medication that researchers had hoped would reduce the risk of arterial renarrowing after stenting has turned in a disappointing performance in a multicenter clinical trial, but the multi-reservoir stent that was used to deliver the drug is still considered promising.

1 Apr 2008

Significant reductions in mortality shown using blood pressure-lowering treatment in very elderly

Lowering the blood pressure of elderly patients could cut their total mortality by a fifth and their rate of cardiovascular events by a third, according to a new study presented at the American College of Cardiology in Chicago and published simultaneously in the New England Journal of Medicine.

1 Apr 2008

Study shows Actos prevented progression of atherosclerotic plaque volume in patients

New data from a clinical trial using intravascular ultrasound (IVUS) technology found that in patients living with type 2 diabetes, ACTOS (pioglitazone HCl) reduced the atherosclerotic burden in the coronary arteries compared to glimepiride, and prevented progression compared to baseline.

1 Apr 2008

Fasting for two days protects healthy cells against chemotherapy

The chemotherapy worked as intended on cancer, extending the lifespan of mice injected with aggressive human tumors, reported a group led by Valter Longo of the University of Southern California.

1 Apr 2008

Appendix removed through a patient's vagina

On March 26, 2008, surgeons at UC San Diego Medical Center removed an inflamed appendix through a patient's vagina, a first in the United States.

From Evident Corporation - Life Sciences 31 Mar 2008

When should children infected with HIV start medication?

The advent of effective medications for treating HIV dramatically improved the outlook for both adults and children infected with HIV who had access to treatment, but the optimal timing for starting treatment remains controversial, particularly in children.

25 Mar 2008