Clostridia News and Research

RSS

Study finds link between dietary sugar and increasing bacterial epidemics

The rising frequency and severity of Clostridium difficile infections may be caused by the commonly used food additive, trehalose, according to Nature.

5 Jan 2018

Genetic test to predict IBD severity in children

Inflammatory bowel disease (IBD) is a chronic relapsing inflammation of the gastrointestinal tract with abdominal pain and diarrhea being the most common symptoms. It can be challenging to diagnose as gastrointestinal complaints mimicking IBD are common.

26 Jul 2017

Scientists reveal key role of excess gut calcium in C. diff infections

It lurks in hospitals and nursing homes, surviving the cleaning crew's attempt to kill it by holing up in a tiny hard shell. It preys upon patients already weak from disease or advanced age.

13 Jul 2017

Study: Child's gut bacteria appears to be influenced by ethnicity and breastfeeding

The bacteria in a child's gut appears to be influenced as early as its first year by ethnicity and breastfeeding, according to a new study from McMaster University.

1 Jun 2017

Mice study yields important clues about protective role of Clostridia strains

Hundreds of thousands of babies worldwide die every year from infections that ravage their digestive systems – including those caused by Salmonella and E. coli bacteria. Millions more get sick.

21 Apr 2017

Could worm infection counter IBD? An interview with Dr Loke and Dr Cadwell

The hygiene hypothesis refers to the idea that decreased exposure to certain infectious agents (because of better hygiene) is the reason why we have seen an increase in inflammatory diseases in the developed world.

17 May 2016

Antibiotic treatment may allow bad bugs to flourish

Antibiotics are essential for fighting bacterial infection, but, paradoxically, they can also make the body more prone to infection and diarrhea.

3 May 2016

Gut microbial imbalance appears to be underlying cause of fatal intestinal illness in premature babies

An imbalance of certain gut microbes appears to be the underlying cause of a frequently fatal intestinal illness in premature babies, according to new research led by Washington University School of Medicine in St. Louis

9 Mar 2016

Researchers reveal link between the microbiome of young mice and later onset of autoimmune disease

Researchers have revealed that the colonization of the gut of young mice by certain types of bacteria can lead to immune responses later in life that are linked to disease.

19 Jan 2015

Lactobacillus-containing probiotics can improve lupus symptoms

Lactobacillus species, commonly seen in yogurt cultures, correlate, in the guts of mouse models, with mitigation of lupus symptoms, while Lachnospiraceae, a type of Clostridia, correlate with worsening, according to research published ahead of print in Applied and Environmental Microbiology.

21 Oct 2014

Bacteria may depend more on gastrointestinal age than on environmental factors in babies

Scientists believe babies are born with digestive systems containing few or no bacteria. Their guts then quickly become colonized by microbes — good and bad — as they nurse or take bottles, receive medication and even as they are passed from one adoring relative to another.

12 Aug 2014

Scientists examine part of sample consisting of non-human DNA

Much of what we know about Oetzi - for example what he looked like or that he suffered from lactose intolerance - stems from a tiny bone sample which allowed the decoding of his genetic make-up.

16 Jul 2014

Freiburg researchers discover molecule that smuggles toxins from intestinal pathogens into human cells

Prof. Dr. Dr. Klaus Aktories and Dr. Panagiotis Papatheodorou from the Institute of Experimental and Clinical Pharmacology and Toxicology of the University of Freiburg have discovered the receptor responsible for smuggling the toxin of the bacterium Clostridium perfringens into the cell.

17 Apr 2014

Decreased bacterial diversity in gut linked with CRC risk

Decreased diversity in the microbial community found in the human gut is associated with colorectal cancer, according to a new study published December 6 in the Journal of the National Cancer Institute.

9 Dec 2013

NYU Langone Medical Center researchers find link between gut bacteria and colorectal cancer

In one of the largest epidemiological studies of human gut bacteria and colorectal cancer ever conducted, a team of researchers at NYU Langone Medical Center has found a clear association between gut bacteria and colorectal cancer. The study, published today in the Journal of the National Cancer Institute, discovered that colorectal cancer patients had fewer beneficial bacteria and more harmful bacteria than people without the disease.

6 Dec 2013

University of Granada researchers patent new treatment for acne

University of Granada scientists have patented a new treatment for acne that is based on completely natural substances and is much more effective than artificial formulas because it does not create resistance to bacteria and has no secondary effects.

23 May 2013

Presence of certain bacteria in stomach microbiota can prevent pathology from H. pylori

Mice with different naturally occurring stomach bacteria have distinct susceptibilities to disease caused by Helicobacter pylori, the well-known cause of ulcers in humans, according to a study published online ahead of print in the journal Infection and Immunity.

26 Mar 2013

Researchers discover cell receptor for CDT toxin of C. difficile bacterium

A research group led by Freiburg pharmacologist Prof. Dr. Klaus Aktories and their American colleagues have discovered the cell receptor for the toxin CDT of the bacterium Clostridium difficile.

27 Sep 2011

C. sporogenes bacterium could be used as vehicle to deliver drugs in frontline cancer therapy

A bacterial strain that specifically targets tumours could soon be used as a vehicle to deliver drugs in frontline cancer therapy. The strain is expected to be tested in cancer patients in 2013 says a scientist at the Society for General Microbiology's Autumn Conference at the University of York.

5 Sep 2011

Hospital acquired Clostridium difficile bug defense system identified

American researchers have discovered the process by which the cells in the gut fight off toxins produced by a hospital bug - Clostridium difficile. Writing in Nature Medicine, they showed how a chemical - GSNO - deactivated a toxin from Clostridium difficile which causes inflammation and diarrhea. They hope to use their findings to develop a treatment for C. difficile.

23 Aug 2011