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UAB researchers report lack of predictability for fecal microbial transplants without prior antibiotic therapy

A fecal microbial transplant -; giving a recipient fecal matter from a donor to change the recipient's gut microbial community in the colon -; has been a successful last resort therapy for people with recurrent Clostridium difficile infection after multiple rounds of suppressive antibiotics have eliminated the recipient microbial community.

4 Nov 2022

Gut-innervating nociceptors found to regulate the intestinal microbiota and promote tissue protection

According to a recent study, substance P produced by the nociceptors present in the gut lining confers protection against inflammation and tissue damage by increasing the number of beneficial microbes.

19 Oct 2022

Recent innovations in infectious disease diagnostics

A recent Clinical Biochemistry editorial reports the latest innovations in the field of infectious disease diagnostics.

17 Oct 2022

Genome-based microbiome signature associated with the severity and prognosis of COVID-19 in hospitalized patients

Researchers evaluated the association between guild-level microbiome signature and the severity and prognosis of SARS-CoV-2 infections by a genome-level metagenomic analysis.

21 Sep 2022

The impact of the infant gut microbiome on vaccine efficacy

A new study reports the effect of the infant gut microbiome on vaccine efficacy.

13 Sep 2022

Recent literature reports on the role of the gut microbiome on human health and its effect on diseases

Researchers assessed the role of the gut microbiome in human health and disease.

8 Sep 2022

How does the human gut microbiome impact menopause?

A recent study summarizes available information on the relationship between menopause and the gut microbiome.

24 Aug 2022

Fortified human breastmilk alters the microbiota of low-birth-weight infants

A new study discusses how fortified human milk changes the gut microbiome in these babies.

24 Aug 2022

New preclinical drug candidate shows promise in eradicating gonorrhea bacteria

A new preclinical drug candidate developed by scientists at the Hackensack Meridian Center for Discovery and Innovation (CDI) shows great promise in eradicating the bacteria causing gonorrhea, according to a new publication.

23 Aug 2022

Study yields critical clues for successful inflammatory recovery

Inflammation is the body's first line of defense, occurring as droves of immune cells rush to the site of injury or acute illness to make repairs and stem further damage.

22 Aug 2022

New treatment may help counteract food allergies and inflammatory diseases in future

Although many people with dietary allergies experience mild symptoms when exposed to triggering foods, some face potentially fatal consequences.

22 Aug 2022

Alzheimer’s disease is associated with characteristic gut metabolomic signatures

Scientists review current literature associated with the role of the gut-brain axis in AD pathogenesis.

9 Aug 2022

Exploring the connection between Parkinson's disease and gut microbiota to uncover potential therapeutic targets

Scientists have published a new review focusing on the relationship between PD and gut microbiota.

15 Jul 2022

Gastrointestinal complications caused by SARS-CoV-2

scientists discuss the gastrointestinal complications associated with COVID-19.

7 Jun 2022

ANU research could lead to better treatment options for rare, deadly bacterial infection

New research from The Australian National University could lead to better treatment options for a rare but very lethal type of bacterial infection.

20 May 2022

Five medical organizations release new guidance for preventing hospital-acquired pneumonia

In the second in series of updates on guidance for infection control in acute-care hospitals, five medical organizations are recommending best practices for preventing hospital-associated pneumonia. Pneumonia is the most common and deadly healthcare-associated infection.

20 May 2022

Studying immunomodulatory effects of microbiota helps design prophylactic and therapeutic interventions against COVID-19

Researchers reviewed the potential clinically relevant mechanisms by which microbiota and microbiota-derived metabolites influence the host immune responses to SARS-CoV-2 infection.

3 May 2022

Researchers demonstrate how a narrow-spectrum antibiotic selectively targets C. diff

Most antibiotics are double-edged swords. Besides killing the pathogen they are prescribed for, they also decimate beneficial bacteria and change the composition of the gut microbiome.

6 Apr 2022

Furin inhibitors as potential therapies to combat SARS-CoV-2 and other diseases

Furin inhibitors as potential therapeutics for treating COVID-19 and other diseases, wherein furin is integral for their pathogenicity and progression.

29 Mar 2022

New therapy makes immunologically 'cold' tumors hot enough for immune attack

Pancreatic cancer is notoriously difficult to cure or even treat. Now, a new strategy devised by scientists at Albert Einstein College of Medicine has succeeded in making pancreatic tumors visible to the immune systems of mice and vulnerable to immune attack, reducing cancer metastases by 87%.

23 Mar 2022