Clostridium botulinum News and Research

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New discovery could expand the possibilities for medical use of Botox

PSI researchers have discovered a surprising trick that could expand the possibilities for medical use of botulinun toxin A1, better known under the name Botox, as an active agent.

18 Dec 2023

Botulism strikes during Rugby World Cup: How sardines benched eight fans in Bordeaux

During the 2023 Rugby World Cup in Bordeaux, France, a food-borne botulism outbreak affected eight people who consumed home-canned sardines at the same restaurant. The report emphasizes the importance of quick diagnosis and public health notifications to control large-scale outbreaks.

17 Oct 2023

Study reveals potential bioterrorism agents and urges enhanced biosecurity measures

Research paper provides pathogen incidences for potential bioterrorism agents in the Netherlands from 2009 to 2019. The study highlights the need for biosecurity measures based on the observed incidences.

15 Jun 2023

Modified Botox can alleviate chronic pain without risk of paralysis or addiction

A modified form of Botox could give long-term pain relief to patients with chronic nerve injury pain, according to a new study.

11 Apr 2023

Researchers develop mathematical model to prevent botulism

Food producers can use a mathematical model developed at the National Food Institute, Technical University of Denmark, to ensure their products do not cause botulism. It is the most comprehensive model of its kind.

27 May 2021

New approach to tame botulinum toxin for drug delivery

While rare, botulism can cause paralysis and is potentially fatal. It is caused by nerve-damaging toxins produced by Clostridium botulinum -- the most potent toxins known.

8 Jan 2021

Researchers discover new source of botulinum neurotoxin

A new source of the botulinum neurotoxin was discovered by Canadian and American scientists in a strain of animal gut bacteria known as Enterococcus faecium.

27 Jan 2018

Researchers discover new type of botulinum neurotoxin from unexpected source

Researchers from the Quadram Institute have identified genes encoding a previously undiscovered version of the botulinum neurotoxin in bacteria from a cow's gut.

12 Jan 2018

TSRI scientists discover potential new therapy to stop deadly botulinum neurotoxin

Botulinum neurotoxin is probably best known to Americans as BOTOX, a cosmetic medicine, rather than as a cause of potentially dangerous foodborne illnesses.

26 May 2017

Scientists develop in vitro stem cell-based bioassay for detecting biological activity of BoNTs

Scientists at the Institute for Infectious Diseases, University of Bern have developed an in vitro stem cell-based bioassay grown on multi-electrode arrays capable of detecting the biological activity of Clostridium botulinum neurotoxins.

28 Feb 2017

Scientists decipher details of cloaking proteins that protect the toxin that causes botulism

Scientists at the U.S. Department of Energy's Brookhaven National Laboratory and collaborators at Stony Brook University and the Institute of Advanced Sciences in Dartmouth, Massachusetts, have discovered new details about how "cloaking" proteins protect the toxin that causes botulism, a fatal disease caused most commonly by consuming improperly canned foods.

7 Dec 2015

Gene therapy may offer significant advantages in prevention of botulism exposure

The current method to treat acute toxin poisoning is to inject antibodies, commonly produced in animals, to neutralize the toxin. But this method has challenges ranging from safety to difficulties in developing, producing and maintaining the anti-serums in large quantities.

30 Aug 2014

Scientists decode key molecular gateway for toxin that causes botulism

U.S. and German scientists have decoded a key molecular gateway for the toxin that causes botulism, pointing the way to treatments that can keep the food-borne poison out of the bloodstream.

12 Oct 2013

Allergan Licenses Rights To Medytox Candidates, In Up-To-$362M Deal

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26 Sep 2013

IFR scientists mine the genome of C. botulinum to reveal new information about toxin genes

The toxin that causes botulism is the most potent that we know of. Eating an amount of toxin just 1000th the weight of a grain of salt can be fatal, which is why so much effort has been put into keeping Clostridium botulinum, which produces the toxin, out of our food.

15 May 2013

Clostridium botulinum News and Research

New discovery could expand the possibilities for medical use of Botox

Botulism strikes during Rugby World Cup: How sardines benched eight fans in Bordeaux

Study reveals potential bioterrorism agents and urges enhanced biosecurity measures

Modified Botox can alleviate chronic pain without risk of paralysis or addiction

Researchers develop mathematical model to prevent botulism

New approach to tame botulinum toxin for drug delivery

Researchers discover new source of botulinum neurotoxin

Researchers discover new type of botulinum neurotoxin from unexpected source

TSRI scientists discover potential new therapy to stop deadly botulinum neurotoxin

Scientists develop in vitro stem cell-based bioassay for detecting biological activity of BoNTs

Scientists decipher details of cloaking proteins that protect the toxin that causes botulism

Gene therapy may offer significant advantages in prevention of botulism exposure

Scientists decode key molecular gateway for toxin that causes botulism

Allergan Licenses Rights To Medytox Candidates, In Up-To-$362M Deal

IFR scientists mine the genome of C. botulinum to reveal new information about toxin genes

Juice products from Juices Incorporated have potential health risk, FDA warns

New technique developed at MU may make food contamination testing more rapid, accurate

Researchers call for botulism testing in sick and healthy cows

Sandia researchers develop SpinDx medical diagnostic tool

Novel strategy for neutralizing unwanted molecules and clearing them from the body

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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