Clostridium Difficile News and Research

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Clostridium difficile is a type of bacterium found in human and animal waste. Clostridium difficile is a common cause of diarrhea that occurs in hospitals. It can also cause diarrhea or other intestinal disorders in patients treated with antibiotics.

Doctors identify patients at high risk of Clostridium difficile

Doctors have developed and validated a clinical prediction rule for recurrent Clostridium difficile ( C. difficile ) infection that was simple, reliable and accurate, and can be used to identify high-risk patients most likely to benefit from measures to prevent recurrence.

1 Apr 2009

Clostridium difficile infection in primary care

The epidemiology of Clostridium difficile infection (CDI) is changing rapidly and has been marked by a significant increase in incidence and severity.

23 Mar 2009

Review of hospital infection control strategies

Hand-washing, a clean environment, appropriate infection barriers and early identification of patients at high risk of colonization with a transmissible microorganism remain the essential measures to prevent and control infection.

16 Mar 2009

Scientists debug Clostridium difficile

An international team of scientists, led by Monash University researchers, has uncovered the workings of a superbug that kills elderly hospital patients worldwide - a discovery that has the potential to save lives and health care systems billions of dollars each year.

2 Mar 2009

Gene technology to fight Clostridium difficile

Scientists at The University of Nottingham are leading a major European study to unravel the genetic code of one of the most lethal strains of hospital acquired infections.

19 Jan 2009

New report shows high Clostridium difficile infection rates in U.S. hospitals

Consumers Union called on hospitals today to take more aggressive steps to protect patients from Clostridium difficile (C.-diff.) infections in light of a new report showing that they are much more common than previous estimates had indicated. As the rate of hospital acquired C.-diff. infections has jumped in recent years, an increasing number of patients have developed antibiotic-resistant strains of the infection that are more difficult to treat and more deadly.

11 Nov 2008

Phase 2 trial of treatment of C-difficile-associated diarrhea shows promise

Medarex, Inc. and The Massachusetts Biologic Laboratories (MBL) of the University of Massachusetts Medical School (UMMS) today announced that a Phase 2 trial of an anti- C. difficile antibody combination treatment in patients with C.

4 Nov 2008

Current hospital tests for Clostridium difficile not accurate enough

Current hospital tests for the bacterium Clostridium difficile (C difficile) are not accurate enough and a new two-stage process should be introduced to avoid misdiagnosis and its consequences.

2 Nov 2008

Targanta Therapeutics presents preclinical data on Oritavancin against Clostridium difficile infection

Targanta Therapeutics Corporation has released the in vivo data from a preclinical study comparing the activity of its antibiotic drug candidate, oritavancin, to vancomycin in a hamster model of Clostridium difficile infection.

26 Oct 2008

Maggots the key to fighting superbugs

Scientists at Swansea University in Wales have discovered that maggots may hold the key to fighting superbugs.

5 Aug 2008

Superbug breakthrough

The week the government's chief medical officer for England, Sir Liam Donaldson, has announced that the NHS aims to create immunisation against two of the most common superbugs, MRSA and Clostridium difficile, within the next decade. But a research team led by University of Sunderland scientists has made a major breakthrough in the fight against a deadly hospital infection which kills tens of thousands of people every year, and it will be available within the next year.

17 Jul 2008

New British consortium to tackle healthcare associated infections

Just over 8% of all hospital inpatients in England develop a healthcare associated infection, with this figure rising to 23% in intensive care units. Preventing and controlling the transmission of infection is a key priority for those involved in healthcare.

16 Jul 2008

Online courses boost infection control skills that could prove vital in a pandemic

Online courses are helping staff to develop the skills they need to tackle hospital-acquired infections, such as MRSA and C.difficile, and this expertise could also prove vital in a pandemic, according to a study published in the latest issue of the UK-based Journal of Advanced Nursing.

10 Jul 2008

Clostridium difficile closes hospital ward

An outbreak of Clostridium difficile (C. difficile) in a Scottish hospital is causing concern despite claims from health authorities that the outbreak is under control.

23 Jun 2008

Misoprostol off-label use may have led to deaths

Preliminary U-M studies indicate that oral use of RU-486's companion drug misoprostol is safe, but vaginal use may undermine body's immune responses

16 Jun 2008

Clostridium difficile killed on exposure to surfaces made of copper and its alloys, brass and bronze

Scientists in the Environmental Healthcare Unit at the University of Southampton in the U.K. have found that infectious bacterium Clostridium difficile is killed when exposed to surfaces made of copper and its alloys, brass and bronze. The results of the study have been published in the February 2008 issue of the Journal of Hospital Infection.

3 Jun 2008

New research into superbug Clostridium difficile

New research into the toxins, virulence, spread and prevention of the superbug Clostridium difficile is reported in the June special issue of the Journal of Medical Microbiology. These findings will play a crucial role in providing us with ammunition in the fight against a sometimes deadly pathogen.

1 Jun 2008

Lotion which glows under ultraviolet light lights up nasty bacteria

A team of Canadian scientists using a lotion which glows under ultraviolet light have shown that up to a third of patient toilets are not properly cleaned. Their findings, published in BioMed Central's journal, BMC Infectious Diseases, also show that spores from the nasty bacteria Clostridium difficile (C. difficile) linger in the loo even when it has been thoroughly wiped down.

11 May 2008

New deadly superbug Steno an ever-increasing threat

Scientists in the Britain say hospitals could be facing an increasing threat from yet another deadly bacterial infection with the potential to rapidly develop a resistance to drugs.

8 May 2008

MRSA in hospital intensive care -- what's growing where?

Researchers are finding out which bugs grow in intensive care units to develop a novel sampling regime that would indicate the threat of MRSA and other superbugs in the environment, scientists heard (Monday 31 March 2008) at the Society for General Microbiology's 162nd meeting being held this week at the Edinburgh International Conference Centre.

31 Mar 2008