Cold Sores News and Research

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Results from a nested randomized controlled trial for BCG vaccination against recurrent herpes labialis

Researchers examined the effect of Bacillus Calmette-Guérin (BCG) vaccination on attenuating herpes labialis (cold sore) recurrences.

14 Sep 2023

Brain organoids provide new insights into HSV-1 encephalitis

The herpes simplex virus-1 can sometimes cause a dangerous brain infection. Combining an anti-inflammatory and an antiviral could help in these cases, report scientists with the Rajewsky and Landthaler labs and the Organoid Platform at the Max Delbrück Center in Nature Microbiology.

22 Jun 2023

Plant based compound peruvoside may be able to prevent up to 12 medically important viruses

Peruvoside, a plant-based compound that is commonly used to treat heart failure, has been discovered to be able to prevent up to 12 medically important viruses, all originating from different virus families.

22 Jun 2023

Viral shedding rate declines rapidly during the first year among people with HSV-1 genital infections

People with a genital infection of the herpes simplex virus type 1 (HSV-1), which usually causes cold sores, frequently shed the virus in the first months after infection, raising the risk that they might spread the virus to sexual partners during this time.

24 Oct 2022

Dentists need to be aware of and alert to oral monkeypox symptomology, warn experts

Monkeypox is an increasing worldwide problem recently declared a public health emergency in the United States. Among classical symptoms that include fever, muscle aches, lymph node swelling and rash are oral lesions present in up to 70% of cases.

22 Aug 2022

Stress accelerates aging of the immune system

Stress - in the form of traumatic events, job strain, everyday stressors and discrimination - accelerates aging of the immune system, potentially increasing a person's risk of cancer, cardiovascular disease and illness from infections such as COVID-19, according to a new USC study.

13 Jun 2022

Genetically modified herpes virus can be used in the fight against cancer

Viruses can make animals and humans sick - or healthy: Researchers at the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB have succeeded in genetically modifying the herpes simplex virus type 1, which triggers painful cold sores, in such a way that it can be used in the fight against cancer in the future.

1 Jun 2022

Viral microRNA acts as a master regulator to induce the reactivation of dormant herpesviruses

Dormant herpesviruses induce their reactivation via a previously unknown cellular mechanism mediated by a viral microRNA. Würzburg researchers show this in the journal "Nature".

5 May 2022

Cytomegalovirus herpesvirus can accelerate the decline of the immune system, study finds

A research team at the University of Córdoba is studying the alterations that occur in the immune system's T lymphocytes with respect to age and in relation to the cytomegalovirus herpesvirus.

29 Nov 2021

Peptoids could one day cure or prevent herpes, COVID-19

In addition to antibodies and white blood cells, the immune system deploys peptides to fight viruses and other pathogens.

24 Aug 2021

Antiviral strategy using synthetic peptoid has promising implications for fighting infection

Scientists have manufactured a synthetic form of peptide to combat viral infections, with tests already conducted on HSV-1 as well as SARS-CoV-2.

24 Aug 2021

New peptide-like molecules could treat herpes, COVID-19, and the common cold

Among the powerful biochemicals of the human immune system, peptides are one of the best.

24 May 2021

HSV-1 infection induces strain-specific transcriptional differences in infected neurons

Why do some people with cold sores around their lips experience painful lesions, while others have no symptoms at all, yet still spread the virus? A new study conducted at Penn State finds that these differences could be due to variations in the way certain strains of herpes simplex (HSV-1) -- the virus that causes cold sores, as well as genital herpes -- activate gene expression in neurons.

29 Mar 2021

Study sheds light on the recurrence of herpes simplex virus

Researchers at the University of Virginia School of Medicine have shed light on what causes herpes simplex virus to flare up, explaining how stress, illness and even sunburn can trigger unwanted outbreaks.

12 Feb 2021

Researchers identify key gene necessary for cells to consume and destroy viruses

A team led by UT Southwestern researchers has identified a key gene necessary for cells to consume and destroy viruses. The findings, reported online today in Nature, could lead to ways to manipulate this process to improve the immune system's ability to combat viral infections, such as those fueling the ongoing COVID-19 pandemic.

17 Dec 2020

Study: Genetically edited form of herpes simplex virus outperforms leading vaccine candidate

A genetically edited form of a herpes simplex virus -- rewired to keep it from taking refuge in the nervous system and eluding an immune response -- has outperformed a leading vaccine candidate in a new study from the University of Cincinnati, Northwestern University and the University of Nebraska-Lincoln.

6 Nov 2020

Cold Sores News and Research

Results from a nested randomized controlled trial for BCG vaccination against recurrent herpes labialis

Brain organoids provide new insights into HSV-1 encephalitis

Plant based compound peruvoside may be able to prevent up to 12 medically important viruses

Viral shedding rate declines rapidly during the first year among people with HSV-1 genital infections

Dentists need to be aware of and alert to oral monkeypox symptomology, warn experts

Stress accelerates aging of the immune system

Genetically modified herpes virus can be used in the fight against cancer

Viral microRNA acts as a master regulator to induce the reactivation of dormant herpesviruses

Cytomegalovirus herpesvirus can accelerate the decline of the immune system, study finds

Peptoids could one day cure or prevent herpes, COVID-19

Antiviral strategy using synthetic peptoid has promising implications for fighting infection

New peptide-like molecules could treat herpes, COVID-19, and the common cold

HSV-1 infection induces strain-specific transcriptional differences in infected neurons

Study sheds light on the recurrence of herpes simplex virus

Researchers identify key gene necessary for cells to consume and destroy viruses

Study: Genetically edited form of herpes simplex virus outperforms leading vaccine candidate

Gene editing approach removes oral herpes

Scientists decode herpes simplex virus 1

Artificial 'candy canes' block viral entry and infection

Harvard scientists demonstrate possible strategy for achieving herpes virus control

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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