Colorectal News and Research

RSS

Liver transplant recipients face increased risks of developing cancer

A new Canadian study comparing cancer rates of liver transplant patients to those of the general population has found that transplant recipients face increased risks of developing cancer, especially non-Hodgkin's lymphoma and colorectal cancer.

4 Nov 2008

Biothera initiates second phase of metastatic colorectal cancer trial

Biothera has announced today it began dosing patients in the second arm of its metastatic colorectal cancer (mCRC) trial in August.

16 Oct 2008

Women require less tobacco exposure than men to increase colon cancer risk

While smoking poses a health threat to both men and women, women require less tobacco exposure than men to have a significant increased risk for colorectal cancer, according to new research presented at the 73rd Annual ACG Scientific Meeting in Orlando.

6 Oct 2008

Lilly to acquire ImClone Systems for $6.5 billion

Eli Lilly and Company and ImClone Systems Inc. today announced that the boards of directors of both companies have approved a definitive merger agreement under which Lilly will acquire ImClone through an all cash tender offer of $70.00 per share, or approximately $6.5 billion.

6 Oct 2008

Most young adults under 50 unlikely need colorectal screening

Young adults without a family history of bowel disease are unlikely to develop adenomas, the colorectal polyps most likely to lead to cancer, according to new research directed by scientists at the Johns Hopkins Kimmel Cancer Center. The finding supports current cancer screening guidelines recommending adults in general undergo screening colonoscopies starting at age 50.

2 Oct 2008

Discovery of genetic link between obesity and colon cancer risk

A new study reveals the first-ever genetic link between obesity and colon cancer risk, a finding that could lead to greater accuracy in testing for the disease, said a researcher at the University of Alabama at Birmingham (UAB).

30 Sep 2008

Molecule provides new understanding of cause of colon cancer

Scientists investigating a molecule known to play a key role in causing colon cancer have made a series of ground-breaking discoveries that could have major implications for future treatment of the disease, responsible for 655,000 deaths worldwide per year. Their findings are published in the journal Cancer Research.

30 Sep 2008

Surgical treatment provides new option for some colorectal cancer patients

Research out of Wake Forest University School of Medicine suggests that a surgical technique not traditionally used in advanced abdominal cancer may be a viable treatment option for some patients previously thought to be untreatable, offering the real possibility of extending survival for those patients.

30 Sep 2008

Gap in black, white new cancer diagnoses narrowing in Missouri; mortality rate gap falling more slowly, study finds

The gap between blacks and whites in Missouri for newly diagnosed cancers is narrowing in part because of an overall decline in smoking and an increase in cancer screenings, according to a study to be published early next year in the journal Missouri Medicine, the AP/St. Louis Post-Dispatch reports.

29 Sep 2008

New results help predict treatment response in colorectal cancer

Genetic testing can identify a group of patients with advanced colorectal cancer who are likely to survive on average twice as long if treated with the drug cetuximab, late breaking results show.

16 Sep 2008

Inherited one-hit gene mutation provides new opportunity for colon cancer prevention

More than 30 years ago, Alfred Knudson Jr., M.D., Ph.D., revolutionized the field of cancer genetics by showing that a person must lose both their paternal and maternal copies of a particular class of cancer-inhibiting genes, called tumor-suppressor genes, in order to develop cancer.

15 Sep 2008

Scientists discover common variants in the human genome conferring risk of bladder cancer

Scientists at deCODE genetics and colleagues at Radboud University Medical Center in the Netherlands today report the discovery of two common single-letter variants in the human genome (SNPs) that confer increased risk of urinary bladder cancer.

14 Sep 2008

Many colorectal cancer survivors do not receive recommended follow-up screening

A new analysis reveals that fewer than half of older patients successfully treated for colorectal cancer receive the recommended screening schedule to detect any recurrence of cancer.

10 Sep 2008

Computerized reminder system drove up colon cancer screening rates

A computerized reminder system used in community-based primary care doctors' offices increased colorectal cancer screening rates by an average of 9 percent, according to a new study from the University of Michigan Health System.

7 Sep 2008

FDA grants IND for Davanat to treat breast cancer patient

Pro-Pharmaceuticals, Inc. has announced that the U.S. Food and Drug Administration (FDA) has granted an Investigational New Drug (IND) application for use of Davanat in combination with 5-FU to treat a breast cancer patient at the Brown Cancer Center in Louisville, Kentucky. Davanat also is being administered in Phase II clinical trials for first-line treatment of colorectal and biliary cancer patients.

28 Aug 2008

Obesity raises risks of serious gastrointestinal diseases

The prevalence of obesity and overweight in the United States coupled by the increased risk of gastrointestinal diseases related to obesity raises serious implications for the health of Americans. Several scientific studies in the August issue of The American Journal of Gastroenterology examine the association between obesity and the risk of colorectal cancer and gastroesophageal reflux disease, or GERD.

19 Aug 2008

Discovery of major genetic cause of colorectal cancer

About one-third of colorectal cancers are inherited, but the genetic cause of most of these cancers is unknown. The genes linked to colorectal cancer account for less than 5 percent of all cases.

14 Aug 2008

Experimental chemo shows promise in treating advanced non-small cell lung cancer

A combination of chemotherapy agents that have been tested in other tumor types appears to be a promising alternative to standard treatment for advanced non-small cell lung cancer, according to a report in the August 15 issue of Clinical Cancer Research, a journal of the American Association for Cancer Research.

12 Aug 2008

Cannabinoid cell surface receptor plays a tumor-suppressing role in human colorectal cancer

CB1 is well-established for relieving pain and nausea, elevating mood and stimulating appetite by serving as a docking station for the cannabinoid group of signaling molecules. It now may serve as a new path for cancer prevention or treatment.

3 Aug 2008

Cancer patients not given enough information about survival benefits of palliative chemotherapy

Two thirds of cancer patients receive little or no information about the survival benefits of having palliative chemotherapy before making a decision about treatment, according to a study published today on bmj.com.

31 Jul 2008