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New study expands immunotherapy eligibility for colorectal and endometrial cancer patients

A new study shows thousands more patients diagnosed with colorectal and endometrial cancers could benefit from immunotherapy than are currently offered it.

29 Dec 2023

Insilico Medicine develops new AI-generated FGFR2/3 inhibitor for tissue-agnostic solid tumors

Insilico Medicine ("Insilico"), a generative artificial intelligence (AI)-driven clinical-stage drug discovery company, today announced the nomination of ISM8001, a novel molecule targeting FGFR2/3 for the treatment of tissue-agnostic solid tumors bringing the total number of PCCs nominated in 2023 to six.

28 Dec 2023

Next-gen sequencing identifies thousands of cancer patients missing out on immunotherapy

Brigham researchers' findings from next-generation sequencing suggest that revising current cancer care guidelines could allow approximately 6,000 more patients in the U.S. to benefit from immunotherapy treatment each year

28 Dec 2023

Simple mail trick doubles liver cancer screening rates for high-risk patients

Liver cancer screening among patients with cirrhosis almost doubled when they were mailed a signed order from their specialist, according to a new study from the Perelman School of Medicine at the University of Pennsylvania.

22 Dec 2023

“Forever chemicals” could contribute to cancer metastasis in living organisms

In a new study by researchers at the Yale School of Public Health, two "forever chemicals" spurred cancer cells in the lab to migrate to new positions, an indication that the chemicals could contribute to cancer metastasis in living organisms.

18 Dec 2023

Study points to the possibility of using cholesterol-lowering drugs to treat aggressive colorectal tumors

Hard-to-detect colorectal pre-cancerous lesions known as serrated polyps, and the aggressive tumors that develop from them, depend heavily on the ramped-up production of cholesterol, according to a preclinical study from researchers at Weill Cornell Medicine.

18 Dec 2023

Unlocking radiation resistance: Missing protein key to suppressing cancer-fighting cells

A new study finds that radiation therapy (RT) suppresses a key protein called bone morphogenetic protein and activin membrane-bound inhibitor (BAMBI) and activates immune suppressive cells.

15 Dec 2023

Outrageous hospital cost for colonoscopies compared to smaller clinics

U.S. hospitals charge facility fees for colonoscopy procedures covered by private health insurance that are on average approximately 55 percent higher than facility fees billed by smaller clinics known as ambulatory surgical centers, according to a study led by researchers at the Johns Hopkins Bloomberg School of Public Health.

15 Dec 2023

Wnt signaling holds promise for tailored immunotherapy in microsatellite-instable colorectal cancer

Colorectal cancer presents with varying clinical characteristics due to tumor heterogeneity. Microsatellite instability (MSI), present in 10%-15% of CRC cases, indicates a different clinical trajectory than microsatellite stable (MSS) patients.

15 Dec 2023

Targeting cholesterol metabolism for the treatment of serrated colorectal neoplasms

13 Dec 2023

Study: Risk of dying from cancer depends on where you live in England

The risk of dying from the 10 forms of cancer with the largest death toll for men and women varies massively depending on the district in England where people live, according to a study published in The Lancet Oncology.

11 Dec 2023

A class of diabetes medications may reduce the risk of colorectal cancer

A groundbreaking study by researchers at Case Western Reserve University suggests a class of medications used to treat type 2 diabetes may also reduce the risk of colorectal cancer (CRC).

7 Dec 2023

Rising colorectal cancer risk in young adults calls for earlier screening, study suggests

Study reveals an increase in adenomas and advanced adenomas in younger adults, alongside a rise in colorectal cancer incidence in males under 50, suggesting a need for earlier screening, particularly in men.

7 Dec 2023

Less than five minutes of daily physical activity could prolong life in people with inoperable lung cancer

Lung cancer kills more people globally each year than any other type of cancer, however new Curtin University-led research has found less than five minutes of daily physical activity could be linked with prolonged life in people living with inoperable forms of the disease.

7 Dec 2023

Link between gut dysbiosis and chronic diseases explored in new study

Study explores the ecological causes of gut dysbiosis and its link to human diseases, revealing how imbalances in gut microbiota composition, influenced by host-derived factors like oxygen and nitrate, contribute to various chronic conditions.

5 Dec 2023

Simple bean diet intervention demonstrates significant prebiotic effects

The impact of incorporating canned navy beans into the regular diet for eight weeks.

5 Dec 2023

UCLA researchers win NCI grants to advance liquid biopsy for early detection of cancer

Researchers from the UCLA Health Jonsson Comprehensive Cancer Center have received two grants totaling $9.1 million from the National Cancer Institute to advance liquid biopsy technologies for the early detection of cancer, which can significantly improve treatment outcomes and reduce the number of deaths caused by the disease.

4 Dec 2023

AI transforms colonoscopy: Boosting detection rates, slashing miss rates in cancer screening

Researchers in China have demonstrated through a systematic review and meta-analysis that AI-based methods significantly enhance adenoma detection rates and reduce miss rates during colonoscopies, potentially improving colorectal cancer screening and reducing mortality.

3 Dec 2023

Combining AI, ctDNA, and histopathology for improved treatment stratification in colorectal cancer

Combining artificial intelligence-generated digital pathology tools, conventional histopathological assessment and circulating tumor DNA (ctDNA) analysis can improve treatment stratification of patients with colorectal cancer after surgery.

1 Dec 2023

Navy beans may improve gut health and metabolism in colorectal cancer survivors

Incorporating navy beans into the diet of colorectal cancer (CRC) survivors has the potential to positively impact both gut and host health by modulating markers linked to obesity and disease, according to new research from The University of Texas MD Anderson Cancer Center.

30 Nov 2023

Colorectal News and Research

New study expands immunotherapy eligibility for colorectal and endometrial cancer patients

Insilico Medicine develops new AI-generated FGFR2/3 inhibitor for tissue-agnostic solid tumors

Next-gen sequencing identifies thousands of cancer patients missing out on immunotherapy

Simple mail trick doubles liver cancer screening rates for high-risk patients

“Forever chemicals” could contribute to cancer metastasis in living organisms

Study points to the possibility of using cholesterol-lowering drugs to treat aggressive colorectal tumors

Unlocking radiation resistance: Missing protein key to suppressing cancer-fighting cells

Outrageous hospital cost for colonoscopies compared to smaller clinics

Wnt signaling holds promise for tailored immunotherapy in microsatellite-instable colorectal cancer

Targeting cholesterol metabolism for the treatment of serrated colorectal neoplasms

Study: Risk of dying from cancer depends on where you live in England

A class of diabetes medications may reduce the risk of colorectal cancer

Rising colorectal cancer risk in young adults calls for earlier screening, study suggests

Less than five minutes of daily physical activity could prolong life in people with inoperable lung cancer

Link between gut dysbiosis and chronic diseases explored in new study

Simple bean diet intervention demonstrates significant prebiotic effects

UCLA researchers win NCI grants to advance liquid biopsy for early detection of cancer

AI transforms colonoscopy: Boosting detection rates, slashing miss rates in cancer screening

Combining AI, ctDNA, and histopathology for improved treatment stratification in colorectal cancer

Navy beans may improve gut health and metabolism in colorectal cancer survivors

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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