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UT Southwestern study reveals structural information for major brain receptor

UT Southwestern researchers today published the first atomic structure of a brain receptor bound to a drug used to reverse anesthesia and to treat sedative overdoses.

28 Jun 2018

Study opens new potential avenue for treating ovarian cancer

Researchers at Houston Methodist Research Institute and The University of Texas MD Anderson Cancer Center have found a prescription drug, Calcitriol, approved by the Food and Drug Administration for the treatment of calcium deficiency and kidney diseases, may increase the likelihood of surviving ovarian cancer.

14 Jun 2018

UCLA researchers have blueprint of telomerase that plays major role in cancer, aging

Cancer, aging-related diseases and other illnesses are closely tied to an important enzyme called "telomerase." UCLA researchers report in the journal Cell the deepest scientific understanding yet of this once-mysterious enzyme, whose catalytic core -- where most of its activity occurs -- can now be seen in near atomic resolution.

7 Jun 2018

NCI selects Arizona State University to lead new cancer research

Arizona State University has been awarded more than $8.5 million over five years from the National Cancer Institute to establish the Arizona Cancer and Evolution Center.

6 Jun 2018

New way of grouping atoms could herald novel materials, drugs and computers

Scientists have found a new way of joining groups of atoms together into shape-changing molecules - opening up the possibility of a new area of chemistry and the development of countless new drugs, microelectronics and materials with novel characteristics.

22 May 2018

Research findings could lead to new therapies to curb ovarian cancer metastasis

In order to spread their destruction, ovarian cancer cells must break free from their tumor home, travel through the fluid in the peritoneal cavity and attach to the outside of the abdominal organs--surfaces that are, by necessity, not sticky.

9 May 2018

OU researchers receive $5.7 million NIH grant to accelerate antibiotic discovery

University of Oklahoma professors, Helen Zgurskaya and Valentin Rybenkov, and team are addressing the challenge and critical need for new antibiotics that can fight infections caused by the multi-drug resistant bacterium, Pseudomonas aeruginosa, considered an urgent threat by the Centers for Disease Control and Prevention.

7 May 2018

Study examines how higher-order gene combinations help maintain normal cell physiology

We inherit many traits from our parents including the color of our eyes and hair. Unfortunately, we also inherit risk factors for certain diseases such as cancer, heart disease, and diabetes. Understanding those genetic connections can help prevention efforts and develop new life-saving treatments to combat these diseases.

20 Apr 2018

Screening strategies could reduce multiple myeloma prevalence, mortality

Multiple myeloma is a rare incurable disease that is diagnosed in more than 30,000 people each year in the United States.

27 Mar 2018

Novel motion capture-like technology for tracking how proteins fold into certain shape

In many modern animated movies, the trick to achieving realistic movements for individual characters and objects lies in motion-capture technology.

13 Feb 2018

Researchers solve crystal structure for enzyme that plays key role in DNA methylation

A research team led by a biochemist at the University of California, Riverside has solved the crystal structure for an enzyme that plays a key role in DNA methylation, the process by which methyl groups are added to the DNA molecule.

7 Feb 2018

RCSI to lead major study for finding new ways to treat colorectal cancer patients

RCSI is leading an international team of scientists on a major research study “COLOSSUS” which aims to provide new and more effective ways to classify and treat patients with colorectal cancer.

2 Feb 2018

CureMatch’s co-founder is co-author of new article in Cancer Discovery journal

Igor F. Tsigelny, Ph.D., Co-founder and Chief Strategic Officer at CureMatch and research professor at University of California, San Diego, is a co-author of “Genomic landscape of cell-free DNA in patients with colorectal cancer” in Cancer Discovery along with group of colleagues from Duke University Medical Center, University of Texas MD Anderson Cancer Center, Massachusetts General Hospital Cancer Center and Department of Medicine, Harvard Medical School, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, Caris Life Sciences, and Guardant Health, Inc. organized by the Drs. Ryan B. Corcoran and Scott Kopetz.

27 Jan 2018

Supercomputers help scientists to devise cancer models for predicting individual treatment outcomes

Attempts to eradicate cancer are often compared to a "moonshot" -- the successful effort that sent the first astronauts to the moon.

3 Jan 2018

Researchers discover new way to attack drug-resistant prostate cancer cells

In most cases, prostate cancer is cured by surgical removal of the tumor and/or by radiotherapy. However, 20% of patients will need treatment to remove tumor cells but this treatment ceases to be effective after two or three years and the cancer develops further.

13 Dec 2017

Computational Modeling News and Research

UT Southwestern study reveals structural information for major brain receptor

Study opens new potential avenue for treating ovarian cancer

UCLA researchers have blueprint of telomerase that plays major role in cancer, aging

NCI selects Arizona State University to lead new cancer research

New way of grouping atoms could herald novel materials, drugs and computers

Research findings could lead to new therapies to curb ovarian cancer metastasis

OU researchers receive $5.7 million NIH grant to accelerate antibiotic discovery

Study examines how higher-order gene combinations help maintain normal cell physiology

Screening strategies could reduce multiple myeloma prevalence, mortality

Novel motion capture-like technology for tracking how proteins fold into certain shape

Researchers solve crystal structure for enzyme that plays key role in DNA methylation

RCSI to lead major study for finding new ways to treat colorectal cancer patients

CureMatch’s co-founder is co-author of new article in Cancer Discovery journal

Supercomputers help scientists to devise cancer models for predicting individual treatment outcomes

Researchers discover new way to attack drug-resistant prostate cancer cells

Researchers use novel computational tool to understand complex disease processes

First 7T MRI system receives FDA clearance for clinical use in the United States

Study shows that the brain uses supramodality to estimate confidence in different senses

BU scientist wins $231,000 AHA award to improve cardiovascular therapies

Scientists stop formation of protein clumps linked to ALS and frontotemporal dementia

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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