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New approach identifies epigenetic changes in leukemia cells for patients undergoing ibrutinib treatment

Many new anti-cancer drugs inhibit proteins that are essential for the proliferation of cancer cells. One example is ibrutinib, an innovative therapy for chronic lymphocytic leukemia first approved in 2014.

29 Jan 2019

A Light Source in Quantitative Analysis: What Role Does it Play?

In this interview, Claudia Jaffe discusses the importance of illuminators in microscopy and the different types of light used in life science research.

From Lumencor, Inc 7 Jan 2019

University of Wuerzburg implements new turnkey confocal imaging system

Technology innovators in super-resolution microscopy, Amsterdam-based Confocal.nl,reports on the implementation of a new turnkey confocal imaging system in the laboratory of Professor Markus Sauer at the University of Würzburg.

From Confocal.nl 29 Nov 2018

Using smartphone confocal microscopes to stop cancer

Dongkyun "DK" Kang was in the shower a few years ago when inspiration struck, and he became interested in the idea of imaging human tissue in vivo, or on a living person, using a smartphone attached to a microscope.

20 Nov 2018

Special care should be taken with drugs that inhibit epigenetic factors, study suggests

A team headed by ICREA researchers Salvador Aznar Benitah and Fran Supek concludes that care should be taken with drugs that inhibit epigenetic factors.

20 Nov 2018

Study reveals unknown mechanism that protects tumor cells from NK cell-mediated cytotoxicity

Cancer cells have evolved multiple escape strategies to circumvent the body's immune defenses such as the attack by Natural Killer (NK) cells which normally swiftly kill abnormal cells by releasing cytotoxic products.

24 Oct 2018

Researchers discover new structure in human cells

A new structure in human cells has been discovered by researchers at Karolinska Institutet in Sweden in collaboration with colleagues in the UK.

22 Oct 2018

Researchers identify molecule that plays key role in bacterial communication, infection

Carnegie Mellon University researchers have identified a molecule that plays a key role in bacterial communication and infection.

12 Oct 2018

New method for studying the cell nucleus could improve disease detection

Researchers at New York University have found a way to measure the physical properties of the nucleus and its constituents in live human cells.

5 Oct 2018

Study shows how cellular waste disposal processes also promote inflammation

A study conducted at the University of California has revealed how cells use G-protein-coupled receptors (GPCRs) and their waste disposal systems to mediate inflammation.

19 Sep 2018

Study gives new insights into how cells leverage GPCRs to control inflammation

G-protein-coupled receptors are everywhere in our bodies. They are embedded in our cell membranes, where they act as signal transducers, allowing cells to respond to their external environments.

19 Sep 2018

New imaging center opens at the University of California San Diego

The Nikon Imaging Center, a collaborative microscopy center that provides local researchers with access to the latest imaging technologies, opened September 13, 2018 at the University of California San Diego.

14 Sep 2018

Researchers use virtual reality goggles to study human anatomy

Tucked away in the back room of a Johns Hopkins research building, a computer hums quietly at a seemingly modest setup of a desktop and a pair of goggles.

6 Sep 2018

Study provides insights into how harmful white blood cells form during tuberculosis

Insights into how harmful white blood cells form during tuberculosis infection point to novel targets for pharmacological interventions, according to a study published in the open-access journal PLOS Pathogens by Valentina Guerrini and Maria Laura Gennaro of Rutgers New Jersey Medical School, and colleagues.

31 Aug 2018

VTCRI study may disrupt conventional understanding about how electrical activity travels in the heart

Scientists at the Virginia Tech Carilion Research Institute have found evidence that may disrupt conventional understanding about how electrical activity travels in the heart -; a discovery that potentially can lead to new insight into medical problems such as heart arrhythmia and sudden cardiac death.

27 Aug 2018

Study unravels cellular and molecular mechanisms behind dermal condensate formation

Hair growth is regulated by a small cluster of hair-specific fibroblasts, the dermal papilla. But exactly how dermal papilla forms has remained elusive until now.

20 Aug 2018

Study reveals key role of actin cytoskeletal dynamics in supporting immune cell function

In order to move, a body needs a strong scaffold. This is not only true on a macroscopic level, where animals rely on skeletons to support their muscles.

26 Jul 2018

Scientists study adverse effects of carbon, silicon nanotubes and carbon nanofibers

Nanoparticles with a wide range of applying, including medicine, damage cells of microalgae Heterosigma akashivo badly. This algae species is widely spread in the Russian Far East marine area. The acute toxic effect exhibited at concentrations of 100 mg/l of carbon nanotubes and silicon nanotubes in the sea- or fresh water.

19 Jul 2018

Researchers scale up fluorescence imaging technique to analyze larger areas

Researchers have scaled up a powerful fluorescence imaging technique used to study biological processes on the cellular level. Previously limited to samples just millimeters in area, the expanded approach can analyze samples with areas up to 4 square centimeters.

27 Jun 2018

Study provides blueprint of how fruit flies can be used to screen potentially pathogenic human genes

It all began with one young patient; a 7-year old boy who was born without a thymus, an important organ of the immune system, and without functional immune cells. The boy also presented with cardiac and skeletal defects, dysmorphic craniofacial features and some signs of autistic behaviors.

23 May 2018