Conjugation News and Research

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How Can CPNs Revolutionize Medical Diagnostics?

At MEDICA 2022, NewsMedical spoke with Andy Chaloner about Stream Bio's conjugated polymer nanoparticle technologies that have the potential to revolutionize the medical and life sciences sectors, from diagnostics to clinical imaging.

From Stream Bio 25 Nov 2022

Pt(IV)-conjugated drug-delivery system shows efficacy in glioblastoma therapy

A recent study demonstrated a novel method for delivering anti-cancer drugs, conjugated to modified cell-penetrating peptides across the blood-brain barrier, in mice to treat glioblastoma.

18 Nov 2022

Licorice compounds proposed as effective candidates for treatment of COVID-19

Researchers describe the different mechanisms by which licorice active ingredients target SARS-CoV-2.

8 Sep 2022

Photocatalyst-based ViraMap platform maps SARS-CoV-2 spike protein interactions on the cell surface

Researchers performed the photocatalytic mapping of the SARS-CoV-2 spike protein-host cell membrane interactions.

7 Sep 2022

DNA origami as an alternative platform to display the RBD of SARS-CoV-2

Researchers demonstrated DNA origami as a potential platform to display the SARS-CoV-2 receptor-binding domain.

23 Aug 2022

What risk factors are associated with post-acute sequelae of SARS-CoV-2?

Researchers explored the risk factors correlated with post-acute sequelae of SARS-CoV-2.

23 Aug 2022

Re-defining the limits of single batch assay stabilisation

In response to increasing demand for stabilised molecular diagnostic assays, we have significantly increased our single batch lyophilised reagent bead manufacturing throughput to 300,000 reactions per freeze drying run and are now progressing towards a capacity of 100 million tests per annum.

From Biofortuna Limited 22 Aug 2022

Researchers discover a molecular switch that promotes pancreatic cancer metastasis

More than 62,000 people in the United States will be diagnosed with pancreatic cancer by the end of this year, with the vast majority having a deadly and aggressive subtype known as pancreatic ductal adenocarcinoma (PDA).

27 Jun 2022

Novel luminescent biosensor detects SARS-CoV-2 spike protein using cell phone camera

In a recent study posted to the bioRxiv* pre-print server, researchers developed a novel Binding Activated Tandem split enzyme (BAT) biosensor for the detection of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein.

16 Jun 2022

New FR-targeting, micropinocytosis-mediated bioconjugate attacks K-Ras mutant pancreatic cancer

Often undetected until it has progressed to an advanced stage, pancreatic ductal adenocarcinoma (PDAC) is a lethal cancer.

6 Jun 2022

SK bioscience's typhoid vaccine licensed for export by Korean Ministry of Food and Drug Safety

The International Vaccine Institute (IVI) and SK bioscience announced today that SK bioscience obtained an export license from the Korean Ministry of Food and Drug Safety for SK's typhoid vaccine 'SKYTyphoid' which they jointly developed.

12 May 2022

Evaluating nano alum as a substitute for conventional alum-based vaccine adjuvant

Researchers evaluated the performance and safety of nano alum adjuvant as next-generation coronavirus disease 2019 (COVID-19) vaccine antigens.

28 Apr 2022

Researchers seek to understand how microbes in the GI tract help people resist pathogens

Published in Nature Communications, research from the University of Minnesota and Mayo Clinic sought to understand how microbial communities help people resist pathogens.

8 Apr 2022

Study evaluates colorimetric sensors for SARS-CoV-2 detection using gold nanoparticles

A new study reported the development of colorimetric sensors for the detection of SARS-CoV-2 ribonucleic acid-dependent RNA polymerase, envelope, and spike genes.

21 Mar 2022

Lateral flow assays: The possibilities beyond COVID-19

In this interview, News-Medical talks to Andre Alfaro from nanoComposix (now a Fortis Life Sciences company) about the possibilities lateral flow assays offer in the post-covid healthscape.

From nanoComposix 17 Mar 2022

Canopy Biosciences launches next-generation ChipCytometry™ instrument for spatial biology with sub-cellular resolution

Canopy Biosciences, a Bruker Company, today announced the commercial launch of the CellScape™ system, the next generation in ChipCytometry™ instrumentation, advancing the cutting-edge for quantitative in situ spatial phenotyping.

From Bruker Nano Surfaces and Metrology 7 Mar 2022

Peptide-based vaccine fails to protect mice against SARS-CoV-2 despite T cell response

A recent study observed that peptide-based vaccination against SARS-CoV-2 failed to protect mice against COVID-19, albeit eliciting T cell responses.

28 Feb 2022

Study explores the boosting of SARS-CoV-2 adenovirus vaccine-induced immunity by capsid decoration

Researchers demonstrated that decorating the capsid surface of adenovirus vaccine vectors with a newly discovered protein superglue, DogTag/DogCatcher generates potent SARS-CoV-2-specific humoral and cellular immunity.

24 Feb 2022

Imaging microscopy shows killer T-cells targeting SARS-CoV-2 spike protein

Researchers demonstrate how cytotoxic T-lymphocytes (CTLs) with specificity for SARS-CoV-2 eliminate multiple infected targets.

30 Jan 2022

An assessment of pH-sensitive cationic lipid nanoparticles for drug delivery

A recent review looks at the molecular design of pH-sensitive cationic lipids and their applications for various tissues and cell types.

7 Dec 2021