Coronary Artery Bypass Graft News and Research

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Study finds no decrease in access to medical care for sicker patients needing CABG surgery

New UC Davis research has found that patients scheduled to undergo coronary artery bypass graft (CABG) surgery in California were just as ill in 2003 - when public reporting of performance data for this particular surgery began - as in 2006, evidence that "report cards" did not cause doctors or hospitals to turn away sicker patients.

23 Apr 2010

Researchers evaluate new treatment for coronary heart disease

Some patients with heart muscles seriously affected by coronary heart disease may soon be able to benefit from an innovative treatment.

13 Apr 2010

Masimo PVI predicts hemodynamic effects of PEEP in mechanically ventilated patients

Masimo, the inventor of Pulse CO-Oximetry™ and Measure-Through Motion and Low Perfusion pulse oximetry, announced today that a new clinical study published in the March 2010 issue of Anesthesia & Analgesia, shows Masimo PVI successfully predicts the hemodynamic effects of Positive End-Expiratory Pressure in mechanically ventilated patients after cardiac surgery.

1 Apr 2010

OrbusNeich's Genous Bio-engineered R stent demonstrates long term clinical efficacy

OrbusNeich today announced that 12 month follow up data from real world patients demonstrated long term clinical efficacy of the company's Genous Bio-engineered R stent.

18 Mar 2010

Primary results of CABG sub-analysis presented at ACC meeting

AstraZeneca (NYSE: AZN) today announced results of a new analysis of the PLATO (A Study of PLATelet Inhibition and Patient Outcomes) study which showed there were fewer deaths in patients with acute coronary syndromes (ACS) who took the investigational oral antiplatelet ticagrelor (BRILINTA™/BRILIQUE™) within seven days prior to having heart bypass surgery (coronary artery bypass graft, CABG) compared to those who took clopidogrel.

17 Mar 2010

Angioplasty: Complexity of heart disease, gender and body size influence cumulative radiation skin dose

Body size, gender and the complexity of heart disease significantly influence how much cumulative radiation skin dose that patients receive during percutaneous coronary intervention (PCI) therapy, also known as angioplasty, according to a new Mayo Clinic study. The study was undertaken as a quality control initiative to reduce the potential radiation risks of cancer to patients and PCI operators.

16 Mar 2010

MAQUET's VASOVIEW EVH reduces rates of leg infection in CABG patients

MAQUET Cardiovascular LLC, a leading provider of cardiovascular technologies, today announced that study results published in the January 2010 Annals of Thoracic Surgery demonstrated that coronary artery bypass graft (CABG) patients who undergo Endoscopic Vessel Harvesting (EVH) demonstrate similar long-term clinical outcomes as patients who undergo traditional "open" vein harvest (OVH) but have significantly reduced rates of leg infection.

16 Mar 2010

Boston Scientific announces results from HORIZONS AMI trial assessing Express bare-metal stent

Boston Scientific Corporation today announced results from an analysis of one-year subset data from the HORIZONS AMI trial assessing the impact of diabetes on clinical and angiographic outcomes in heart attack patients treated with the TAXUS® Express2™ Paclitaxel-Eluting Stent System or the Express® bare-metal stent.

16 Mar 2010

New trial comparing drug-eluting stents to bypass graft surgery in left main coronary artery disease patients

The announcement of a new clinical trial, EXCEL (Evaluation of Xience Prime versus Coronary Artery Bypass Surgery for Effectiveness of Left Main Revascularization), that will compare drug-eluting stents to coronary artery bypass graft surgery in patients with left main coronary artery disease, was made today at "Optimizing PCI Outcomes: Evolving Paradigms," a symposium presented by the Cardiovascular Research Foundation.

15 Mar 2010

Following existing cholesterol-lowering target guidelines can prevent more heart disease-related incidents

Only half of all patients at high risk of heart disease are given correct targets for lowering their cholesterol levels according to a study of 25,250 patients in Germany published online today (Thursday 11 March) in the European Heart Journal.

11 Mar 2010

Adherence to lipid-lowering guidelines may help reduce cardiovascular deaths

11 Mar 2010

Ischemix commences CMX-2043 Phase 2a trial for prevention of peri-operative ischemia-reperfusion injury

Ischemix today announced the initiation of patient accrual in a multi-center Phase 2a clinical trial of CMX-2043 for the prevention of peri-operative ischemia-reperfusion injury in patients undergoing elective percutaneous coronary intervention (PCI) procedures. CMX-2043 is a cardio-protective drug that combines Akt pathway-mediated cell survival effects and anti-oxidant activity in a single small molecule.

9 Mar 2010

Bypass surgery: New method of growing arteries could lead to non-invasive option for treatment

A new method of growing arteries could lead to a "biological bypass"-or a non-invasive way to treat coronary artery disease, Yale School of Medicine researchers report with their colleagues in the April issue of Journal of Clinical Investigation.

9 Mar 2010

Ligand Pharmaceuticals acquires Metabasis Therapeutics

Ligand Pharmaceuticals Incorporated announced that it has completed the acquisition of Metabasis Therapeutics, Inc. (NASDAQ:MBRX), following approval of the transaction by Metabasis stockholders yesterday. As a result, Ligand gains a fully funded partnership with Roche, additional pipeline assets and drug discovery technologies and resources. The transaction was first announced on October 27, 2009.

28 Jan 2010

MAQUET Cardiovascular initiates study evaluating EVH in CABG compared to open vein harvesting

MAQUET Cardiovascular LLC, a leading provider of cardiovascular technologies, today announced the initiation of the OPTION (Optimal Improvement of Vein Graft Patency Long Term by the Implementation Of Novel Endoscopic Harvesting Techniques) study. This clinical trial is designed to evaluate the equivalence of Endoscopic Vessel Harvesting (EVH) in Coronary Artery Bypass Graft (CABG) surgery compared with historical data for open vein harvesting. David Moore, M.D., of THE HEART HOSPITAL Baylor Plano is the principal investigator for the OPTION trial.

27 Jan 2010

Erectile dysfunction can be strongly related to the development of CVD

In the first study of its kind, New England Research Institutes, Inc. (NERI) in collaboration with the Division of Cardiology, San Francisco General Hospital and the University of California, San Francisco tested whether erectile dysfunction (ED) can be used to reclassify patients according to their future risk of developing cardiovascular disease (CVD) beyond traditional risk factors (such as smoking, high blood pressure, high cholesterol, etc).

20 Jan 2010

MAQUET Cardiovascular signs a two-year contract with Novation

MAQUET Cardiovascular LLC, a leading provider of cardiovascular technologies, announced today that it has signed a guaranteed two-year contract with Novation, one of the nation's largest group purchasing organizations, to be the sole source provider of surgical devices for beating heart cardiac surgery.

25 Nov 2009

Results from Phase IIa clinical trial evaluating VT-111 reported by Viron Therapeutics

Viron Therapeutics Inc., a biotechnology company pioneering the development of immune-modulating protein therapeutics derived from pathogens, today reported results from a Phase IIa clinical trial evaluating VT-111 (Serp-1), an anti-inflammatory protein derived from the myxoma virus.

19 Nov 2009

Dual niacin-statin therapy improves blood cholesterol levels but does not diminish plaque buildup

The routine prescription of extended-release niacin, a B vitamin (1,500 milligrams daily), in combination with traditional cholesterol-lowering therapy offers no extra benefit in correcting arterial narrowing and diminishing plaque buildup in seniors who already have coronary artery disease, a new vascular imaging study from Johns Hopkins experts shows.

19 Nov 2009

Telephone-delivered collaborative care for treatment of depression in post-CABG patients improve outcomes

Patients who received telephone-delivered collaborative care for treatment of depression after coronary artery bypass graft surgery reported greater improvement in measures of quality of life, physical functioning and mood than patients who received usual care, according to a study in the November 18 issue of JAMA. The study is being released early online because of its presentation at an American Heart Association scientific conference.

17 Nov 2009

Coronary Artery Bypass Graft News and Research

Study finds no decrease in access to medical care for sicker patients needing CABG surgery

Researchers evaluate new treatment for coronary heart disease

Masimo PVI predicts hemodynamic effects of PEEP in mechanically ventilated patients

OrbusNeich's Genous Bio-engineered R stent demonstrates long term clinical efficacy

Primary results of CABG sub-analysis presented at ACC meeting

Angioplasty: Complexity of heart disease, gender and body size influence cumulative radiation skin dose

MAQUET's VASOVIEW EVH reduces rates of leg infection in CABG patients

Boston Scientific announces results from HORIZONS AMI trial assessing Express bare-metal stent

New trial comparing drug-eluting stents to bypass graft surgery in left main coronary artery disease patients

Following existing cholesterol-lowering target guidelines can prevent more heart disease-related incidents

Adherence to lipid-lowering guidelines may help reduce cardiovascular deaths

Ischemix commences CMX-2043 Phase 2a trial for prevention of peri-operative ischemia-reperfusion injury

Bypass surgery: New method of growing arteries could lead to non-invasive option for treatment

Ligand Pharmaceuticals acquires Metabasis Therapeutics

MAQUET Cardiovascular initiates study evaluating EVH in CABG compared to open vein harvesting

Erectile dysfunction can be strongly related to the development of CVD

MAQUET Cardiovascular signs a two-year contract with Novation

Results from Phase IIa clinical trial evaluating VT-111 reported by Viron Therapeutics

Dual niacin-statin therapy improves blood cholesterol levels but does not diminish plaque buildup

Telephone-delivered collaborative care for treatment of depression in post-CABG patients improve outcomes

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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